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Donor conception

For anyone with experience of sperm or egg donation to share support and advice. Please remember this board isn’t for debate about donor conception.

Progesterone sensitivity

2 replies

CalmJadeHiker · 26/01/2025 09:45

Hello,
Have been trawling forums for a few weeks now trying to find anyone else with the same issue but no luck! I'm doing my first cycle of IVF with donor eggs and have struggled to manage the progesterone. Pessaries caused massive swelling and blistering, and injections caused big sore lumps which are still there (although thankfully not sore!) after two months. My clinic has had me on Cyclogest, Crinone and Lubion so far, and I'm now trying Utrogestan which is already causing discomfort after one dose.

Has anyone else ever had these symptoms and did you manage to sort it out?

OP posts:
alijangra · 26/01/2025 13:49

Have you tried the pessaries rectally? Or Progesterone in Oil intramuscular injections?

CalmJadeHiker · 26/01/2025 18:03

Yeah, I tried the Cyclogest both ways but that just made everything a lot worse 🤦 They haven't offered intramuscular injections but I imagine the Lubion would be similar?

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