Booster Shots

[Daisydoor12]

Just read of BBC news about the booster shots for all over 50s and CEV rolled out from next week either Pfizer and Moderna being used. DM had AZ vaccines back in March/April. People who had AZ are they having Pfizer/Moderna? I can’t see any mention of AZ boosters. DM had awful reaction to AZ (yellow carded and GP involved) don’t think she’ll want to change to a different type of vaccine. Where can I find information on mixing vaccines for booster shot? And having 3 vaccinations? To me it seems the government are “putting all their eggs in the vaccine basket” when it has been proven you can catch and pass-on even with the vaccine.

The booster for the vast majority will be a single shot of Pfizer. A few people may get a half-dose of Modena instead.

The mRNA vaccines are preferred as studies showed they give a very good immune response whichever vaccine was given initially (AZ or mRNA). Antibody levels go up around 10-fold after the booster.

If someone has an allergy to the mRNA vaccines AZ can be considered for the booster.

Boosters aren’t compulsory. It’s not yet know if they will be offered regularly after this winter.

As a CEV health worker who was vaccinated last December I am bloody delighted to be getting a booster!

Why is the AZ not being used as a booster? I was vaccinated very early on as a healthcare worker, so I am pleased I will be getting a booster.

Because it’s not as effective.

@LouLou198

Why is the AZ not being used as a booster? I was vaccinated very early on as a healthcare worker, so I am pleased I will be getting a booster.

I think a study has been done that showed mixing vaccines gives a stronger immune response.

Yes, I've read that as well, only Pfizer booster.

Anyone know why that is? Is it admiting that AZ is crap?

I am also uncomfortable with it, I had the AZ (as CV, if I wasn't I'd have had the Pfizer as Under 40) I took the risks of side effects with that one and now being asked to taken the risks with another.

Here www.pharmaceutical-technology.com/features/covid-19-vaccine-mixing-astrazeneca-pfizer/

@Whichjab

Yes, I've read that as well, only Pfizer booster.

Anyone know why that is? Is it admiting that AZ is crap?

I am also uncomfortable with it, I had the AZ (as CV, if I wasn't I'd have had the Pfizer as Under 40) I took the risks of side effects with that one and now being asked to taken the risks with another.

It doesn't seem to be a reflection on AZ - AZ and Pfizer give a much higher response than either vaccine alone. It seems to be more that the two different types of vaccines prime the immune system in different ways.

They said mRNA for the unlucky 500,000 (most compromised) for whom a third shit was announced almost two weeks ago, but who are still awaiting being called for it (told to wait to be notified imminently)

It looks as if those on the list will get their general age related booster faster.

The government continues to overlook the most vulnerable CEV - thus time by leaving the pouiatiin with the idea that something happened fir them, epwhen it really didn't.

I had the 2 doses of AZ and am happy to have Pfizer, but if a mixture of vaccines is better, why not give those who had Pfizer first AZ. I think it’s also a stock issue, we seem to have enough Pfizer for the 12-15 and the boosters.

@nether

They said mRNA for the unlucky 500,000 (most compromised) for whom a third shit was announced almost two weeks ago, but who are still awaiting being called for it (told to wait to be notified imminently)

It looks as if those on the list will get their general age related booster faster.

The government continues to overlook the most vulnerable CEV - thus time by leaving the pouiatiin with the idea that something happened fir them, epwhen it really didn't.

Sorry what?

Because Pfizer-Pfizer or AZ-Pfizer gives better results than Pfizer-AZ.

My comment was to @Mindymomo

@nether yes, well that’s entirely typical.

Does anyone know if people in the old group 6 are getting a booster?

@Egghead68

Because Pfizer-Pfizer or AZ-Pfizer gives better results than Pfizer-AZ.

Has anyone seen studies on this?

Yes

@Wakemeuuuup

Does anyone know if people in the old group 6 are getting a booster?

I think it’s the original first 6 groups who are getting it .

So mixing vaccines is more effective with the exception of Pfizer followed by AZ ? Okay then. I'm not usually swayed by conspiracy theories but has this anything to do with the surplus of Pfizer vaccines we have as a nation.

Also, if you refuse a booster does that mean one is no longer fully vaccinated for the purposes of travel, isolation & night club entry (Scotland) ?

Thank you @Explosivefarts

@LizzieMacQueen as not everyone is being offered the booster at the moment I don’t think they can count it when considering whether someone is fully vaccinated

@BlueberrySugar What Nether is saying is that there are a subset of CEV who are severely immunocompromised and many of them are thought not to have produced antibodies to the first two jabs.

JCVI recommended two weeks ago that these people are given a third dose of vaccine asap that counts as part of their primary dose schedule. They are then likely to get a fourth shot - their booster shot 6 months after this.

But messaging to gps and consultants on this has been slow and confusing. So for some it seems likely that the booster campaign catches them before they get invited for their 3rd primary dose.

Given that much of this cohort are walking around unshielded and without or with few antibodies with a background of high levels of covid in the community, when the community aren't wearing masks or keeping their distance, it's far from ideal and they urgently need their 3rd doses, before the booster campaign so they can be done within days.

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[quote OhYouBadBadKitten]@BlueberrySugar What Nether is saying is that there are a subset of CEV who are severely immunocompromised and many of them are thought not to have produced antibodies to the first two jabs.

JCVI recommended two weeks ago that these people are given a third dose of vaccine asap that counts as part of their primary dose schedule. They are then likely to get a fourth shot - their booster shot 6 months after this.

But messaging to gps and consultants on this has been slow and confusing. So for some it seems likely that the booster campaign catches them before they get invited for their 3rd primary dose.

Given that much of this cohort are walking around unshielded and without or with few antibodies with a background of high levels of covid in the community, when the community aren't wearing masks or keeping their distance, it's far from ideal and they urgently need their 3rd doses, before the booster campaign so they can be done within days.[/quote]
Although what I don’t understand about the third-shot for immunocompromised people is - if they didn’t have an immune response to 2 shots, why would they have an immune response to a third? Is there any evidence they would?

I'm not usually swayed by conspiracy theories but has this anything to do with the surplus of Pfizer vaccines we have as a nation

I’m sure pragmatic factors (using a vaccine we have in stock, keeping things simple) will also play a part in the recommendations.