Alternatives to AstraZeneca vaccine for under 40s “could be considered” amid rise in blood clots 2

[Whichjab]

Just starting another thread as so much information still coming out. Interesting that Germany have just allowed AZ for all that want it.

Note, this is not an Anti-Vaccs thread. It is just a discussion about alternatives.

*Sorry should read Moderna or Novavax.

(Do you think the MN edit button will ever arrive)

@SempreSuiGeneris

Indigo the BBC report says 2nd doses will be same again or a shot of Moderna and Novavax. Doesn't look like there will be any Pfizer to AZ mixing. In any case since most 1st dose Pfizer were done earlier there wouldn't be many left to switch to AZ 2nd dose by the time the study reports.

Looks more like another sign of a pivot away from AZ going forward.

That’s Com-Cov 2. Com-Cov 1 is evaluating mixing Pfizer and AZ and due to report very soon.

One way the gov can ensure enough Pfizer and Moderna supply for under-40s is to give over-40s who received Pfizer or Moderna AZ as their second jab.

They may also decide it’s wise to give under-40s who received AZ as their first dose an alternative for their second, given the safety issues.

*Sorry should read Moderna or Novavax.

(Do you think the MN edit button will ever arrive)

I am not comfortable combining vaccines so won't be getting vaccinated again if that is the case.

Ah OK I see.

@NotSoLongGoodbye

I am not comfortable combining vaccines so won't be getting vaccinated again if that is the case.

Me either. The mRNA vaccines get a big boost with the second jab, I don’t see how giving AZ could improve on the 98 and 94% efficacy.

If we had the supply I could definitely see the case for giving AZ first dose people an alternative second dose. But we don’t.

@SempreSuiGeneris

I wish that was the case but that report is re: Com-Cov 2. Com-Cov 1 is evaluating mixing Pfizer and AZ and due to report very soon.

One way the gov can ensure enough Pfizer and Moderna supply for under-40s is to give over-40s who received Pfizer or Moderna AZ as their second jab.

They may also decide it’s wise to give under-40s who received AZ as their first dose an alternative for their second, given the safety issues.

Maybe I’m paranoid but they keep finding ways to shaft the 40-49 bracket.

@SempreSuiGeneris

Indigo the BBC report says 2nd doses will be same again or a shot of Moderna and Novavax. Doesn't look like there will be any Pfizer to AZ mixing. In any case since most 1st dose Pfizer were done earlier there wouldn't be many left to switch to AZ 2nd dose by the time the study reports.

Looks more like another sign of a pivot away from AZ going forward.

That’s Com-Cov 2. Com-Cov 1 is evaluating mixing Pfizer and AZ and due to report very soon.

One way the gov can ensure enough Pfizer and Moderna supply for under-40s is to give over-40s who received Pfizer or Moderna AZ as their second jab.

They may also decide it’s wise to give under-40s who received AZ as their first dose an alternative for their second, given the safety issues.

@SempreSuiGeneris

Indigo the BBC report says 2nd doses will be same again or a shot of Moderna and Novavax. Doesn't look like there will be any Pfizer to AZ mixing. In any case since most 1st dose Pfizer were done earlier there wouldn't be many left to switch to AZ 2nd dose by the time the study reports.

Looks more like another sign of a pivot away from AZ going forward.

I wish that was the case but that report is re: Com-Cov 2. Com-Cov 1 is evaluating mixing Pfizer and AZ and due to report very soon.

One way the gov can ensure enough Pfizer and Moderna supply for under-40s is to give over-40s who received Pfizer or Moderna AZ as their second jab.

They may also decide it’s wise to give under-40s who received AZ as their first dose an alternative for their second, given the safety issues.

Maybe I’m paranoid but they keep finding ways to shaft the 40-49 bracket.

*Sorry should read Moderna or Novavax.

Apologies. Mumsnet seems to be borked. 😂

I am not comfortable combining vaccines so won't be getting vaccinated again if that is the case.

*Sorry should read Moderna or Novavax.

I don't have a lot of knowledge in this area, so please be gentle.

If I have a sister (older by 8 yrs) who had the vaccine and she suffered no side effects, would my immune response to same vaccine be similar because we are related, or is it still fairly random?

Thanks!

I don't have a lot of knowledge in this area, so please be gentle.

If I have a sister (older by 8 yrs) who had the vaccine and she suffered no side effects, would my immune response to same vaccine be similar because we are related, or is it still fairly random?

Thanks!

If we had the supply I could definitely see the case for giving AZ first dose people an alternative second dose.

Definitely. Particularly since the reports about potential efficacy against the variants seems focused on Pfizer. Nothing on whether AZ works. And also, if AZ doesn't prevent mild to moderate infection, people remain unprotected against Long Covid.

Maybe I’m paranoid but they keep finding ways to shaft the 40-49 bracket

Most definitely. Lets not forget, the likelihood of hospitalision or death rises significantly from 45 (not 50). It's likely lots of 40 somethings will have undiagnosed underlying conditions. It's why NHS health checks are at 40. And, there's studies suggesting that it's women in their 40s who are most at risk from Long Covid.

@LetSophieGo
There's nothing to suggest siblings will react the same. Unless I've missed a recent report? I'm sure somebody will be along soon to correct me if I've wrong.

Still going round in circles here. Rang my gp told they only have AZ clinics. Referred back to helpline who yet again insisted they don’t know anything about the details for each centre and that they see the same screen as I do when booking so have no clue if I’m to be offered AZ or Pfizer or what.
So I’m back to square 1. Don’t want AZ. Can’t seem to get anything else. Desperate to be vaccinated.

@Margaritawithlime

Still going round in circles here. Rang my gp told they only have AZ clinics. Referred back to helpline who yet again insisted they don’t know anything about the details for each centre and that they see the same screen as I do when booking so have no clue if I’m to be offered AZ or Pfizer or what. So I’m back to square 1. Don’t want AZ. Can’t seem to get anything else. Desperate to be vaccinated.

Are you in London? I had Moderna at the BDC in Islington. Up until now it’s been Moderna only, and I know they were giving it again there today. Going forward who knows, things seem to be changing fast, but to date it’s been the safest bet I know.

@IndigoC No West Yorkshire - Bradford Leeds area. I know they’ve given it at BRI and Leeds Thackeray museum but neither come up as an option for me when I’ve tried to book

@User657849
Thank you. Interesting. So it looks like none of the vaccines protect against Long Covid? I guess Pfizer or Moderna might be more effective on a herd level though? The majority of the population having a vaccine with over 90% effectiveness reduces the chances of transmission and infection in the first place.

Given that, and the reports on efficacy against the variants only mentioning Pfizer, it's looking increasingly like those who were given AZ should be given a Pfizer (or possibly Moderna) booster.

I have been doing a fair bit of reading about the AZ vaccine recently.

Press/media related sources cause me anxiety as a 47 yr old, but the more scientific information makes quite a bit of sense.

Anyone else with this confusion?

Are there others like me in this thread who really wanted to Pfizer but have just about given up?

I am in the north west and can only make an appointment to go to a large site which is permanently offering AZ to my age range.

The risks do seem very low, but I don't like feeling strong-armed into having no choice, and have been spoken to quite rudely when I have made local enquiries.

@LetSophieGo

I'm feeling a bit like that. I booked once and cancelled as I just couldn't face it though. I'm just hanging in there and waiting at the moment, hoping they'll either offer a choice, or maybe some info will come out about who is more at risk, though at the moment it seems pretty random.

I'm particularly scared to have it though as I live alone and work from home, which could mean if I did have a problem, and couldn't get help myself, it could easily be days before anyone even noticed. But at the same time, I want to be vaccinated and want it over and done with.

@ScarlettSunset

Relate to all of that, especially the bit about living and working from home. It's an extra layer of worry isn't it. I suppose it works in our favour in terms of waiting it out - we're not at much risk in terms of catching Covid.

Part of me is so sick to the back teeth of the endless analysing and anxiety that I'm tempted just to get the AZ and be done with it. I really don't know any more.

@LetSophieGo yes! I walked out on Monday when it was AZ - the guy was a complete arse and pending a complaint to the health board. I rebooked for beginning of June but found a spot for tomorrow which I have. I keep going back and forth on it whether I'll go but feel if I don't I'll be reading and watching data for weeks going round in circles. I live in Scotland not that far from Glasgow and the rate there looks like it's on an upwards trend and I don't want to be that person who delays and catches it. I work on them pharma industry and have worked on drugs with much worse side effect profiles so I really should be more rationale than this!