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Are the rare blood clots associated with AZ linked to an underlying health condition?

92 replies

Tonylepony · 07/04/2021 10:14

Has a link been found between the people who have suffered from these rare blood clots? It seems quite likely the people who have suffered from them are considered vulnerable to coronavirus as the vaccination has not yet been rolled out to younger age groups apart from those in group 6.

OP posts:
Bluntness100 · 07/04/2021 16:21

@BatleyTownswomensGuild

The press statement said, 37 million vaccines given and about 130 cases of clots, none fatal. Still MUCH better odds than COVID-19....
Which press statement, the numbers I heard were very different.
CovidCorvid · 07/04/2021 17:33

Still the risk is waaay lower than COVID

Depends how old you are. For under 30s it seems about equal.

Springchickpea · 07/04/2021 17:37

I am interested in previous covid infection and migraine with aura as risk factors.

SilverGlitterBaubles · 07/04/2021 17:46

There must be enough cases at this point to establish a link or common factor

Littlemiss74 · 07/04/2021 17:58

I’m really anxious now after reading some of this. I have an autoimmune disorder, RA. I’ve had the first AZ vaccine & am due my second any day now. I suffer with health anxiety and have spent the past year worrying about catching covid and am now worried about having the vaccine!🙁

CuriousaboutSamphire · 07/04/2021 18:19

@CovidCorvid

Still the risk is waaay lower than COVID

Depends how old you are. For under 30s it seems about equal.

It wasn't that the risk was equal it was that the RR started to tip more towards the vaccine carrying a 'vanishingly small' additional risk.

Because of where we are in the UK roll out and because of the number if different vaccines we have available the MHRA decided to make a different recommendation for the 18-29 age group.

The recommendation remains (for those with no underlying health issues) 'take the vaccine you are offered' but that this age group would, where possible, be offered a different vaccine.

The headline remains: AZ is safe for everyone. Take the vaccine.

CuriousaboutSamphire · 07/04/2021 18:21

@SilverGlitterBaubles

There must be enough cases at this point to establish a link or common factor
No. Both the EMA and HMRA said that clotting had been found in all age groups and in men and women. Numbers across all age groups aren't high enough to say any particular cohort is at more risk.

But that could change any week, any month...

Iootraw1 · 07/04/2021 22:11

The odds only seem better to get jab if covid is a potential threat for the individual concerned. For those who have already had covid and recovered and for younger people who are at at tiny risk from covid it’s rather different. Also it’s not just one dose of AZ it’s two this time round and then possibly next year again , so having to face this risk each and every time?!!!

ThebirdsAndBeesWhereThere · 07/04/2021 22:18

I'm 50. Had a DVT (long time ago - but don't have Factor 5 Leiden) have
an autoimmune condition (that made me CEV), not on the pill.

Have had Covid and x2 AZ vaccine.

All seems a little pot luck to me.

CuriousaboutSamphire · 08/04/2021 07:42

@Iootraw1

The odds only seem better to get jab if covid is a potential threat for the individual concerned. For those who have already had covid and recovered and for younger people who are at at tiny risk from covid it’s rather different. Also it’s not just one dose of AZ it’s two this time round and then possibly next year again , so having to face this risk each and every time?!!!
Not really.

The vaccines themselves are being 'tweaked' all the time.

We could have a completely different vaccine for boosters

There may be treatment for or identification of those with higher risks

And again, the individual risk is not what JCVI etc look at.

user1471505356 · 08/04/2021 07:49

I find it interesting that Norway noted this two months ago after relatively few doses and in the UK took nearly 20 million doses to respond.

TuckMyWin · 08/04/2021 07:57

The thing I find interesting in all of this is that I know someone who developed a similar condition with low platelets after having had the flu vaccine. She was advised not to have AZ very early on as it’s the same type of vaccine as the flu. These types of side effects are not unique to the COVID vaccine.

LEMtheoriginal · 08/04/2021 08:06

I find it interesting that Norway noted this two months ago after relatively few doses and in the UK took nearly 20 million doses to respond.

THIS with knobs on!!

I had my az jab last week, my anxiety is sky high. I am not having the 2nd jab

nether · 08/04/2021 08:15

the vaccination has not yet been rolled out to younger age groups apart from those in group 6

Point of detail

The vaccination has rolled out to younger people in groups 1 and 2, and also in group 4 (please don't equate the CEV with the elderly - it's not defined by age any more that cat 6 is)

MarshaBradyo · 08/04/2021 08:16

This was posted on another thread

It is useful for looking at relative risk

twitter.com/alex_freeman/status/1379808289278545922?s=21

MarshaBradyo · 08/04/2021 08:17

link

MummyPop00 · 08/04/2021 08:17

Just take low dose aspirin for a period after having AZ to lessen clotting risk maybe?

AbsolutelyPatsy · 08/04/2021 08:18

both my dd have had this due to their jobs, i am concerned, that they still should have the 2nd jab but if they hadnt had the first jab they would be offered a different one, they are under 30

MarshaBradyo · 08/04/2021 08:25

Personally I’m tired of waiting for vaccine so will have AZ when the the delay passes

CuriousaboutSamphire · 08/04/2021 08:33

@user1471505356

I find it interesting that Norway noted this two months ago after relatively few doses and in the UK took nearly 20 million doses to respond.
Partly an "issue per million population" statistic. It was more quickly noticed because of a number of 'oddities' in their stats.

Which is why everyone looked again at their stats, including the UK, who went on to request all GPs etc trawled back through their records to see if, with new symptoms to look for, they had anything to add.

The really interesting thing is that this all happens without fanfare. It is business as usual. There are procedures that have been in place for decades to allow this to happen quickly.

And still some complain, see the boogeyman - as seen in many posts across this topic!

jasjas1973 · 08/04/2021 08:34

@user1471505356

I find it interesting that Norway noted this two months ago after relatively few doses and in the UK took nearly 20 million doses to respond.
I raised this too on another thread & not just Norway, plenty of other countries also, with far fewer doses, picked up this issue.

Doesn't fill me with confidence that we know what we are doing, possible because the roll of the MHRA was really done by the EMA whilst we were in the EU.

MarshaBradyo · 08/04/2021 08:35

Curious yes exactly

jasjas1973 · 08/04/2021 08:37

Appreciate you are a big fan of the govt/mhra @CuriousaboutSamphire
but the bottom line is that 4 weeks ago, we had no cases, denied any link and the line was it was a batch issue or a non issue and the inference being these countries were playing politics.

PandoraP · 08/04/2021 08:39

I commented on the reason Norway was so certain of the link early on. Several factors. A small country where medics are good at reporting and good visibility of reported issues which means hospitals quickly knew what to look out for. 120k has been vaccinated by the vaccine, majority healthcare workers many women. Most of the patients have been treated in the same hospitals by the same doctors.
I very much doubt Norway will use the vaccine again.

MarshaBradyo · 08/04/2021 08:40

possible because the roll of the MHRA was really done by the EMA whilst we were in the EU.

No matter what your view on relative risk this really is unsubstantiated.