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PCOS - Metformin

26 replies

MrsOverthinker25 · 26/08/2026 16:52

Hi,

I have been diagnosed with PCOS, I have moved from England to Wales - I asked my doctor to prescribe me Metformin. My GP stated she cannot prescribe it but will refer me to a gynaecologist and also email them to see if they can give permission for me to start Metformin in the meantime. Annoyingly, my friend in England was prescribed it straight away.

Does anyone have any experience of this and know 1) how long I will roughly have to wait for a gynaecology appointment and 2) how long it will take them to get back to my GP about Metformin?

really hopeful Metformin will help regulate my cycles and allow us to conceive (we have been trying for well over a year now)

thank you! :)

OP posts:
danii95 · 18/09/2026 14:38

Hello!

I also have PCOS been trying to conceive for a year and half. My GP asked an endocrinology consultant for advice about prescribing metformin, but unfortunately they advised against it, and my GP wouldn’t prescribe it either. I think it’s quite hit and miss in the UK when it comes to using it off-label for PCOS😞

I decided to start Mounjaro privately after hearing some really positive things about it for PCOS, as my periods had disappeared for around 8 months. Within a month of starting it, my periods came back, and I’m now ovulating and having regular monthly cycles! I literally swear by it for PCOS if you are able to get it! Good luck with everything!☺️X

MrsOverthinker25 · 20/09/2026 22:29

danii95 · 18/09/2026 14:38

Hello!

I also have PCOS been trying to conceive for a year and half. My GP asked an endocrinology consultant for advice about prescribing metformin, but unfortunately they advised against it, and my GP wouldn’t prescribe it either. I think it’s quite hit and miss in the UK when it comes to using it off-label for PCOS😞

I decided to start Mounjaro privately after hearing some really positive things about it for PCOS, as my periods had disappeared for around 8 months. Within a month of starting it, my periods came back, and I’m now ovulating and having regular monthly cycles! I literally swear by it for PCOS if you are able to get it! Good luck with everything!☺️X

Hey,

Sorry for the delay! do you know why they advised against it? My GP is waiting for Gynae to get back to them, they rejected my referral but my GP thinks it was rejected with advice to start me on metformin. However, been waiting over 3 weeks to find out what Gynae has actually said in the referral letter! I have started it on my own now though as I’m sick of waiting, I purchased it from offline (legit pharmacy) but I have also purchased mounjaro and will start that this week! Good luck to you! 🥰

Im hopeful something positive happens, my next step is to go private if Gynae refuse to prescribe me it! Xx

OP posts:
MrsOverthinker25 · 20/09/2026 22:29

danii95 · 18/09/2026 14:38

Hello!

I also have PCOS been trying to conceive for a year and half. My GP asked an endocrinology consultant for advice about prescribing metformin, but unfortunately they advised against it, and my GP wouldn’t prescribe it either. I think it’s quite hit and miss in the UK when it comes to using it off-label for PCOS😞

I decided to start Mounjaro privately after hearing some really positive things about it for PCOS, as my periods had disappeared for around 8 months. Within a month of starting it, my periods came back, and I’m now ovulating and having regular monthly cycles! I literally swear by it for PCOS if you are able to get it! Good luck with everything!☺️X

Hey,

Sorry for the delay! do you know why they advised against it? My GP is waiting for Gynae to get back to them, they rejected my referral but my GP thinks it was rejected with advice to start me on metformin. However, been waiting over 3 weeks to find out what Gynae has actually said in the referral letter! I have started it on my own now though as I’m sick of waiting, I purchased it from offline (legit pharmacy) but I have also purchased mounjaro and will start that this week! Good luck to you! 🥰

Im hopeful something positive happens, my next step is to go private if Gynae refuse to prescribe me it! Xx

OP posts:
danii95 · 21/09/2026 10:16

They said my BMI wasn’t high enough but PCOS doesn’t just affect people with higher BMI’s, I just feel like they aren’t as clued up on it here! That’s amazing about the Mounjaro and do not blame you about getting it on private prescription I was also going to do the same 🤣

good luck to you too!♥️ I just got put on letrozole by my fertility doctor so fingers crossed 🤞🏻xx

MrsOverthinker25 · 21/09/2026 14:12

danii95 · 21/09/2026 10:16

They said my BMI wasn’t high enough but PCOS doesn’t just affect people with higher BMI’s, I just feel like they aren’t as clued up on it here! That’s amazing about the Mounjaro and do not blame you about getting it on private prescription I was also going to do the same 🤣

good luck to you too!♥️ I just got put on letrozole by my fertility doctor so fingers crossed 🤞🏻xx

Yes that’s not true at all, you can have lean PCOS. I literally had to advise my doctor that my blood’s are consistent with PCOS and worked out my FAI for her, after she said my bloods were fine. She then agreed with me that I have PCOS! Shocking.

I have been prescribed metformin and folic acid today, finally!!

Oooh yay! good news Letrozole! I have heard really good things about that, my BMI is above 35 so I cannot be referred but hoping with mounjaro it’ll bring it down nicely and if I don’t catch by then, Letrozole will help! But finally getting somewhere after so long! So exciting for both of us! Always here if you need to offload or chat! :) Xx

OP posts:
sirensong · 24/09/2026 10:47

Now that PCOS has been renamed PMOS and expressly recognised as primarily a metabolic disorder, doctors may more readily prescribe metformin to address insulin resistance. Which is typically present regardless of BMI.

danii95 · 24/09/2026 10:59

MrsOverthinker25 · 21/09/2026 14:12

Yes that’s not true at all, you can have lean PCOS. I literally had to advise my doctor that my blood’s are consistent with PCOS and worked out my FAI for her, after she said my bloods were fine. She then agreed with me that I have PCOS! Shocking.

I have been prescribed metformin and folic acid today, finally!!

Oooh yay! good news Letrozole! I have heard really good things about that, my BMI is above 35 so I cannot be referred but hoping with mounjaro it’ll bring it down nicely and if I don’t catch by then, Letrozole will help! But finally getting somewhere after so long! So exciting for both of us! Always here if you need to offload or chat! :) Xx

im so happy for you!! That’s great ☺️ and fingers crossed! Thank you lovely! Always here for you too♥️xx

danii95 · 24/09/2026 10:59

sirensong · 24/09/2026 10:47

Now that PCOS has been renamed PMOS and expressly recognised as primarily a metabolic disorder, doctors may more readily prescribe metformin to address insulin resistance. Which is typically present regardless of BMI.

I hope so!🤞🏻

MrsOverthinker25 · 25/09/2026 15:34

sirensong · 24/09/2026 10:47

Now that PCOS has been renamed PMOS and expressly recognised as primarily a metabolic disorder, doctors may more readily prescribe metformin to address insulin resistance. Which is typically present regardless of BMI.

As they should! My GP still isn’t able to prescribe it.
however, gynae instructed my GP to start me on it thankfully 🥰 xx

OP posts:
MrsOverthinker25 · 25/09/2026 15:35

danii95 · 24/09/2026 10:59

im so happy for you!! That’s great ☺️ and fingers crossed! Thank you lovely! Always here for you too♥️xx

Thank you!! How are you doing? I have been super rough from metformin, I am off work because of the side effects at the moment! It’s bloody awful but getting better. Scared about increasing my dose on Monday xx

OP posts:
danii95 · 25/09/2026 15:41

MrsOverthinker25 · 25/09/2026 15:35

Thank you!! How are you doing? I have been super rough from metformin, I am off work because of the side effects at the moment! It’s bloody awful but getting better. Scared about increasing my dose on Monday xx

Im good thank you ♥️ I am just waiting for my period (October 12th) to start letrozole so in a waiting period 🤣 so sorry to hear you are poorly 😞 hopefully it will get better as time goes on 🤞🏻sending lots of love!xx

MrsOverthinker25 · 17/10/2026 20:20

Hey how are you doing? I have an update :) xx

OP posts:
MrsOverthinker25 · 17/10/2026 20:21

not sure why it didn’t attach! Xx

PCOS - Metformin
OP posts:
danii95 · 17/10/2026 20:21

MrsOverthinker25 · 17/10/2026 20:20

Hey how are you doing? I have an update :) xx

Hello! I have just finished my letrozole so just waiting to ovulate now🤞🏻 😱😱 what is the updated?xx

MrsOverthinker25 · 17/10/2026 20:22

Oh fab !! How did you find it? I’ve heard that can also make you feel unwell! Xx

OP posts:
danii95 · 17/10/2026 20:22

MrsOverthinker25 · 17/10/2026 20:21

not sure why it didn’t attach! Xx

OH MY GOODNESS!!! Congratulations!!♥️🥹xx

MrsOverthinker25 · 17/10/2026 20:23

danii95 · 17/10/2026 20:22

OH MY GOODNESS!!! Congratulations!!♥️🥹xx

Thank you so much!!!! Only 10dpo but I just KNEW I was pregnant! I really hope you get your BFP soon! Xxx

OP posts:
danii95 · 17/10/2026 20:24

MrsOverthinker25 · 17/10/2026 20:22

Oh fab !! How did you find it? I’ve heard that can also make you feel unwell! Xx

I was okay apart from the headaches and hot flushes were crazy!! How are you feeling?🥹♥️xx

danii95 · 17/10/2026 20:24

MrsOverthinker25 · 17/10/2026 20:23

Thank you so much!!!! Only 10dpo but I just KNEW I was pregnant! I really hope you get your BFP soon! Xxx

I am honestly so happy for you!! that is amazing ♥️thank you lovely I’m really hoping for this cycle but not getting my hopes up🤣xxx

MrsOverthinker25 · 17/10/2026 20:32

Aww bless you! Nothing worse than that either 😩 I bloody hate a headache, I’ve had one lingering all day! and I cannot stand being hot so I feel for you! 🤍

Thank you so much. It’s been the longest, draining and infuriating 15 months ever, I really did accept at one point that I may just never be pregnant ever again! 🥹🥹

I will keep my fingers crossed for you! I have heard such good things about letrozole 🫶🏻xxx

OP posts:
danii95 · 17/10/2026 20:33

MrsOverthinker25 · 17/10/2026 20:32

Aww bless you! Nothing worse than that either 😩 I bloody hate a headache, I’ve had one lingering all day! and I cannot stand being hot so I feel for you! 🤍

Thank you so much. It’s been the longest, draining and infuriating 15 months ever, I really did accept at one point that I may just never be pregnant ever again! 🥹🥹

I will keep my fingers crossed for you! I have heard such good things about letrozole 🫶🏻xxx

yes they were awful! Thank you so much ♥️ I hope you feel okay the next few weeks and I’ll keep you updated 😘xxx

MrsOverthinker25 · 17/10/2026 20:47

Awww bless you! Hopefully smooth sailing going forward. I know my sister had a rough time when on it as it’s given to cancer patients, she could hardly leave her bed some days and was always having hot flushes, seems terrible!

Aww thank you so much 🤍 yes deffo keep me posted, I’ll be keeping my eye out! 🫶🏻xxx

OP posts:
danii95 · 17/10/2026 20:51

MrsOverthinker25 · 17/10/2026 20:47

Awww bless you! Hopefully smooth sailing going forward. I know my sister had a rough time when on it as it’s given to cancer patients, she could hardly leave her bed some days and was always having hot flushes, seems terrible!

Aww thank you so much 🤍 yes deffo keep me posted, I’ll be keeping my eye out! 🫶🏻xxx

Oh bless her 😭 I hope she’s okay now ♥️ xxx

MrsOverthinker25 · 17/10/2026 21:03

She is getting there thank you so much 🥹 she’s a trooper and has smashed her journey so much, really proud of her. There’s no way I’d be as brave as her 🤣 she’s a bad ass!! Xxx

OP posts:
danii95 · 18/10/2026 11:12

MrsOverthinker25 · 17/10/2026 21:03

She is getting there thank you so much 🥹 she’s a trooper and has smashed her journey so much, really proud of her. There’s no way I’d be as brave as her 🤣 she’s a bad ass!! Xxx

Aww bless her 🥹❤️ she really is!! She should be so proud of herself 🥰 sending you both lots of love xxx

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