Immune/NK cells pred thread #34

[Hopeandfaith1990]

Hi all, started a new thread as the old one was full. Not sure if this is the way to do it but I've c&p'd the list of people on the previous one as much as poss:

Old thread here: https://www.mumsnet.com/talk/conception/5228367-immunenk-cells-pred-thread-33?page=40

@Jecca88
@Gizmo1983
@Deerdancer34
@Objectiontime
@SWMum9
@TammyinCork
@Newbeginnings22023
@Fletchasketch
@Morgan236
@CarpeDiem75
@ALittleLight
@MC8
@venusStarr
@Gizmo1983
@Carportforme
@Meg310532
@Newbeginnings22023
@recurrentmis
@hopefulH
@v60
@lozzmax
@fleur89
@motherofshihtzus
@sunflower360
@kea1990
@sprinkleofbabydust
@star2022
@rumandspinach
@ems123456789
@rainbowsunshine81
@mamaw05
@thornters
@elarcoiris

Midwife appt all good - very cool to hear the doppler, I burst into tears as usual. Hope everyone has a good evening xx

Hi girls...just looking for some advice from anyone that has done super ovulation. This is my second month and both months of doing it my body has gone into a natural surge before they advise to take the trigger shot.

For example this cycle, I went in on the Thursday for my follice scan- two follices measuring 17 and 15.3. Told to take trigger shot at 9pm on Sunday. Then friday morning I got a very positive opk, had also had ewcm for days leading up to this so knew my body would ovulate soon.

I emailed the clinic immediately to see what they advised. Thinking they would say to take the trigger shot that evening as my body had already started a natural surge. Instead they replied at 7pm telling me to have intercourse but stick to the plan of triggering at 9pm on Sunday! With no explanation as to why?! Why would I take the trigger shot AFTER I ovulated? I took the trigger friday evening anyway. This also happened to be the first month x

Hi @ChaE05 it's really confusing isn't it. This happened to me a couple of times as well, I never got to the bottom of it or worked out whether I'd ovulated earlier than they thought I'm afraid. I was tracking my temperatures and it definitely looked from those that I was ovulating before my trigger but they said they didn't go off temp tracking. Tricky!

I’ve not done SO so I’m no expert — but could it because although you’ve had a surge there’s still about 48 hours in which you could ovulate - so the surge doesn’t actually have to mean you ovulate then, you can only really confirm that with tracking temps or having scans?

@Hopeandfaith1990im really in tune with my body and when I ovulate, I get pains. I get ewcm for 5 days before and my period always comes exactly when it should. Once I get a surge I usually ovulate the next day. However even if it did take me 48 hours that would take me to Sunday morning. Triggering Sunday at 9pm is just completely pointless. I feel frustrated that the clinic aren't really explaining their reasons for this despite a few messages sent back and forth. Xx

Ah ok - yes that absolutely is frustrating! Fingers crossed it has worked anyway! Are they against bbt then at CRP?

@Gems2811aghh so frustrating. They just dont seem to be giving a reason as to why. Its alot of money to spend every month if its not being done properly. Were you successful on SO? X

I wasn't, but for an entirely different issue and so don't read anything into my experience with the trigger timings. My ovulation pain on SO dialled up to wanting to call an ambulance bad, which lead me to visiting an endo specialist and finding out I had severe endometriosis and so SO was never going to work for me without a lap first. Can you ask them/your GP to maybe confirm when ovulation has occurred some way? I'm with you on the frustration, it's a lot of money and you want to be getting the timing right

@ChaE05are you speaking with the nurses or are you able to skip them and speak directly with Shehata or Edge?

@Jecca88 24 weeks!!! Just wonderful, I'm so excited for you!!

@LoudAquaMoose Congratulations! I felt a lot better after I had made it to 12 weeks!

@Lalalala77 I am so sorry, I had a PUL after my first 3 miscarriages and I found it really hard. It was an ectopic, if it does end up being an ectopic, don't let the hospital remove your tube unless its absolutely necessary. They were just going to remove mine & it took me researching etc and saying the mass isn't too big to stop them. I really hope you are ok, we're always here for you.

@Hopeandfaith1990 oooo I'm so thrilled for you. Hearing the heartbeat is just magical isn't it!?

@ChaE05 I can't help as this hasn't happened to me but I would wait for your appointment and ask Shehata or Edge directly as the nurses aren't always great with questions like that I've found.

My update - cycle 6 didn't work which I'm heartbroken about.... I feel dreadful towards the end of 10 days of drugs, so I'm thankful not to being doing steroids this time tbh. It was a crap Valentine's Day and start to our holiday in France but there we go!

Lots of love everyone 💗

amazing news on at the midwife appointment @Hopeandfaith1990 i feel like once you have had a good scan the doopler is enough lols. Are you starting to get your bump?

@Deerdancer34 i am so sorry month 6 didn't work and what a sh*tter on holiday. Have you managed to have a nice holiday after?

We got burgled the night before last and they came and broke into house whilst we were asleep upstairs - stole my husbands bike and car - which is just awful timing and honestly being pregnant already makes you feel so vulnerable. Extra costs and admin plus feeling unsafe - wish our dog Archie was still here - this would have never happened. :(

@Jecca88 oh my, I'm so sorry about the burglary - I had a nightmare about it happening to me last night and that was bad enough. We got burgled at my family home on Christmas Eve when I was about 13, it was horrific. So sorry. Are the police being helpful? Do you have ring doorbells or anything? It feels so violating. How are you aside from that? How many weeks are you now?

Yes I do have a bit of a bump to be honest! Its hard though because I was about a size 14-16 pre-pregnancy so its not SUPER obvious but Husband is telling me its there even when I just say I'm bloated etc haha. I've still not made it common knowledge at work so I'm having to dress very intentionally to hide it at the moment. I've got the 20 week scan next week so assuming that goes well I will start telling people at work a bit more which will be a relief. And the kids I teach!

@Deerdancer34 so sorry it didn't happen for you this month :( what is your plan going forward? Was your daughter conceived via SO? Hope the rest of your holiday was good - so hard to switch off from this TTC stuff though :(

Thanks @Hopeandfaith1990 it's just so much of an extra cost that we really don't need right now, not to mention the now sleepless nights i am having - constantly checking our other car is still there and if anyone is in the house.

I was the same, size 14/16 pre pregnancy, i actually feel like i have lost weight but just got it on my belly. My bump only really became noticable after the 20 week mark what i felt. I also have big boobs, so don't know where boobs start and bump began lols. I started wearing the badge when i travel into the office and people generally look but don't ask.

I can't believe you are nearly at 20 weeks - how are you feeling about it? I bet the kids reaction will be soo lovely when you tell them.

@Jecca88 That's awful, you poor thing 🫣 Really horrible not to feel comfortable in your own home... Really hope you're ok.
Once I was off the steroids, we did have a nice holiday thank you. Think I needed the break tbh, so hopefully that will help for this time 🙏

@Hopeandfaith1990 Aww the kids will be sooo excited! The kids I taught kept going, I can hear the baby crying, I said 'I hope not!' and also telling me how the baby can come out two ways - TMI in my opinion 😅
We are going to stick with SO for now, as its been a difficult time with my FIL & brother I'm hoping that's why it's not worked yet...Yes I conceived my daughter through SO, so I'm hoping it'll work again. Very relieved not to be going on steroids straight away this time. I'm 🙏🙏🙏
Good luck for your scan!

Hi ladies,
For anyone who used CRP and had superovulation due to struggling to conceive (as well as carry), how many cycles did it take you to fall pregnant?

I have an app with Shehata next Tuesday finally 🤞🏼

@Roro27 Hello & welcome, first time I conceived 3rd cycle but ended in ectopic. 2nd time I conceived my daughter on 4th cycle. This time I am going into cycle 7 (but I've had a stressful few months). I really liked SO, took a lot of stress away. Apparently Cycles 4-6 are usually the most successful. Do let me know if I can help in any way. Xx

Good luck for your scan this week @Hopeandfaith1990 xxx

Hi all. Sorry didn't mean to go quiet!

Mental health has been tricky recently. I am soooo happy and grateful to be pregnant but I am so scared all of the time of something going wrong :( I don't think I've felt many movements yet either.

I had a midwife mental health appt yesterday and they've referred me to a mental health team called AFLOAT specifically for women pregnant after loss and trauma. I don't think I realised how bad my mental health has gotten but in the appointment yesterday the midwife was quite frank and basically said I shouldn't be living like this (e.g. constantly in fear, not talking about being preg to anyone, having these intrusive thoughts and OCD tendencies). Not blaming my husband at all because we're the same in that we've both just been too scared to talk about it for fear of 'jinxing' it. The midwife yesterday basically said 'your pregnancy doesn't HAVE to be like this, you can have more support and look back on this with happiness rather than anxiety' so hopefully the new referral will help!

Heard the heartbeat yesterday again which was lovely, although she couldn't find it as quickly as before at first which was terrifying. But once found I was able to listen to it for over a minute which was amazing. 20 week scan is on Friday, I will update here afterwards 💜

How are you @Jecca88 @Deerdancer34 @LoudAquaMoose and everyone? xxxx

@Hopeandfaith1990 What a fabulous midwife! I hope it will really help you because it would be lovely for you if you can enjoy the rest of your pregnancy 💓I really found the talking therapy helped tremendously. I think when you start feeling the movements that will be nice too, it was a bit of a strange feeling after 12 week scan because there weren't as many scans and the baby is too small to feel anything yet. Hearing the heartbeat is always so comforting although horrible for you she couldn't find it straight away. We can't wait to hear about your scan tomorrow 😍🥰🥰

I'm in my 2WW.... Fewling nervous... But can't tell you how good I feel being off steroids 😅 Lots of love to you all 💓

Hi girls thought would give you a bit of an update. Moved on to my fourth super ovulation but the the last one was with a clinic out in South Africa who were amazing I got my standard 2 follicles & 12-13m lining but didn’t work again :( it feels so discouraging as it obvs worked the 2nd cycle with Hallie so I keep comparing. But I had a Hyfosy yesterday which showed my tubes/structure/lining etc were all good as I was panicking something had changed since the abruption and c section inside of me. With my previous cycles I have had a third follicle lagging behind so for this fourth cycle in South Africa still I have taken my letrozole as standard but added Gonal-f (75 units) days 4,6,8 and 10 for my last gonal-f tomorrow as she said it should help grow that third follicle alongside the others fingers crossed. I really hope this third cycle works but keep seeing that if it hasn’t worked by like 3-4 the likelyhood of it working goes down? X

Hi all, just popping in quickly to say all was good for the 20 week scan today. They couldn’t get a clear look at a couple of parts so we need to go back for a 2nd attempt next week, because the baby was wriggling so much and had their hands over their face! But generally everything looked good and I’m going to do my best to embrace the positivity!!! Lots of love to all xxxx

Hi @Meg310532 didn’t want to read and run - I don’t have SO experience but it’s good that the Hyfosy went well and I’m wishing you so much luck for your third cycle. You’ve been in my thoughts ❤️ are you living in South Africa? Sorry if you were before, I didn’t realise xx

@Hopeandfaith1990 Congratulations what a huuuge milestone! Now you get the added benefit of an extra scan next week! Are you going to find out what you're having? I'm so so delighted for you and I really hope you will get that extra support 💓

@Meg310532 I'm in the same situation as you, I conceived on 3rd and 4th cycles before (although one ended in a loss) and now I'm on my 7th... CRP have always said they have the most successes between Cycles 4-6 so don't lose heart! It's hard when you have nice follicles and a nice lining but it doesn't work. Wishing you lots of luck for this next cycle 💓

@Deerdancer34 I needed to hear this so bad today thank you hun! Have CRP changed anything with your cycles or have you kept with the same dosage and plan each time ? I didn’t realise the best success was between 4-6 I thought it was before that so it’s really good to hear :)) ! Are you continually getting a few follicles and good lining ?

@Hopeandfaith1990 thanks so much hun! I’m out in SA for 6 weeks my husbands family are all from here :)) back on the 17th March ! So just making the most of the cheap amazing fertility treatments out here xx

@Meg310532 We're keeping everything the same. I increased my dose once previously but I produced too many follicles & so I wasn't allowed to trigger that cycle, so we've decided to keep at 7.5mg. Yes! It is frustrating, Dr E says every time, you respond so well and have a nice lining, so it's maddening its not happened yet. I'm not really sure what our plan is, I'm burying my head in the sand a bit. I feel, it worked once so it'll happen again... I did ask Dr E what the % chance is each cycle and she said 10% which sounded low to me but she said its better than most! Oh and for Cycle 7 I'm not taking steroids for 2WW because you have have a break from them. Lots of love 💓