Interactions with certain antifungals
Nexplanon interacts with certain antifungals, which are drugs used to treat fungal infections.
Examples of antifungals include:
What could happen
Taking certain antifungals while you have the Nexplanon implant could increase your risk of side effects from Nexplanon.
Certain antifungals may keep your body from breaking down etonogestrel properly. (Etonogestrel is the active drug in Nexplanon.) This can lead to high levels of etonogestrel in your system, which can raise your risk of side effects from the implant.
What you can do
If you develop a fungal infection while you have Nexplanon, be sure the doctor treating the infection knows you have the Nexplanon implant. They may avoid prescribing certain antifungals with Nexplanon. Your doctor can recommend an antifungal that won’t affect Nexplanon.
In some cases, your doctor may still prescribe an antifungal that interacts with Nexplanon. For example, they may do so if the antifungal is the best option for treating your specific infection.
If you take an antifungal that interacts with Nexplanon, watch for side effects of Nexplanon.
Examples include acne, breast pain, and headache.