Immune/NK cells - pred thread 28

[myrainbowjourney]

Hi Ladies

New thread 🥰

If you comment to hold your place. I'll try and tag as many as I can xxx

It's really hard getting negative tests @myrainbowjourney ❤️ I hate testing. I hope you managed to get some frer and hope you get good news tomorrow.

The doctor agreed to prescribe the sitagliptin, no biopsy 🙌 can start on my next period which should be just over 2 weeks away. Think we'll give it a couple of months (have 3 months prescription) and can make a plan. Even with this, I feel more hopeful. Xxx

I've just had some light brown discharge and I feel like all hope is lost for this little bean. I know that loads of women get this and it's not an issue, but I can't help but thinking it's all over now. I just feel heartbroken.

@SunDance21 I'm so sorry to hear that. I don't know that there's anything I can say to make you feel better, because I know how anxious you must be feeling. Try and relax as much as you can and maybe call the clinic in the morning?
Sending lots of love xxx

@VenusStarr thank you lovely. I'm pretty sure I know the answer. The cheapie would have shown by now I imagine, it's 10 sensitivity, I'm clutching at straws. Part of me is excited to try with a different dose but terrified it won't work and it's the last chance.

Wow I'm so pleased the doctor agreed to the medication! What a result. You must feel so much lighter mentally! So pleased for you ❤️❤️

I'm sorry @SunDance21 ❤️ I know this feels really scary but I hope that all is well. Can you get in touch with the clinic tomorrow? It's so hard not to go into overdrive, sending you lots of love xxx

🤞 @myrainbowjourney what dose will you try next time? It's OK to have a bit of hope ❤️

Thank you, he did say he'd prefer me to try another biopsy but understood my reason for not wanting to and he was happy to let me try it.
Interestingly, he wasn't supportive of us doing pgs testing of embryos moving forward.
My dh wants me to try these meds and then plan using our last embryo. The meds help the uterus stem cells regenerate so makes sense to give us the best possible chance. Xxx

@VenusStarr negative frer this morning 😢

I'm up to 12.5mg for the last try. They want to try and get more than one follicle on the side with my tube. I have to have my next tracking with Dr S to discuss next steps.

Last chance saloon! It's so rubbish.

How are you doing today?

@SunDance21 how are you lovely?

xxx

Oh @myrainbowjourney I am so sorry ❤️ ❤️ it's so horrible to see that. Sending you a hug.
I'm glad you'll see Dr S soon to talk about a plan. Hopefully the higher dose will help you get more follicles.

I hope you're OK today @SunDance21 ❤️

I'm OK today, I feel like we had a tiny chink of hope again. I'm still anxious about our results but I'm not chasing today xx

Our test results are back. We were expecting a normal, healthy baby girl 💔 😢 I'm in a strange place, because I knew. I'm sad our treatment didn't work again. I'll get in touch with crp tomorrow. We're going to ask for an appointment in a few weeks. I'm interested to hear his thoughts on what went wrong this time, especially as we saw a heartbeat.

I hope you're OK @SunDance21 ❤️ did you speak with the clinic today?

Hope you're doing OK as you can be @myrainbowjourney xx

@VenusStarr I am so so sorry. I’m glad you finally got an answer even if it isn’t what you wanted. I’m so sorry for your loss ❤️

I’m still having light brown spotting. They’ve told me to stop the aspirin. My stress levels are through the roof, I have never felt anxiety like this which can’t be good for the embryo if it is actually okay… I’ve cried 5 times today and I’m not normally a cryer. I keep having light stomach cramps too which isn’t helping.

It’s so hard because you think progesterone etc will stop this…I have read online that many people get a bit of brown spotting with progesterone from irritation to the cervix, but my spotting seems to be at night before I take the tablets.

@myrainbowjourney I’m so sorry it came back negative ❤️ I hope you’re okay.

@myrainbowjourney @VenusStarr @SunDance21 sending lots of love to you all

Oh for goodness sake!! This all makes me so angry! Why is this such a difficult journey for some of us?? It's so unfair.

@VenusStarr I am so sorry to hear about your baby girl. I am sending you so much love.
I hope now Dr S can come up with a plan for next time. I think although it's really hard to hear and comprehend, knowing that your baby was healthy can only help him come up with the best treatment for next time.

@SunDance21 I'm not in the least surprised you're feeling stressed. Did they say anything else? When did you say you are seeing them? Is it next week?
I have read that about progesterone and the cervix. I think if you use them rectally then it can prevent it. Really hoping it subsides for you. Please don't worry about stress affecting your little embryo. it's unnecessary pressure on yourself to not worry about something that is impossible not to worry about. Allow yourself to feel the emotion but also take it day at a time, and remember that right now, you are pregnant 💗

Thank you both and @TheHopefulEgg for your lovely good wishes. I am ok. Like I said I knew it would be negative, just had a little hope as you do.
Looking forward to hearing next steps, and also nervous. I am trying to prepare myself for any eventuality. Maybe if I am told to have a break I can book a holiday or something?
Hoping so much the extra dose will give me lots of lovely follicles but of course, that's no guarantee either.

Sending so much love to you all ❤️❤️❤️ xxx

@myrainbowjourney thank you so much for your message. It just made me cry and I think it was just want I needed to hear. Thank you ❤️

You’re exactly right, the hand some of us are dealt is so unfair.

I think me and my husband are going to go away this weekend just to sort of take our minds off it.

I hate that there is nothing I can do, and no point in a scan at this point as it would probably only increase my anxiety.

Not sure when my next appointment is as I still haven’t been given a date by the clinic. I’ll chase them again tomorrow.

Thank you again ❤️

Hello everyone, I’m new to this thread, but sadly not new to TTC & RPL! I am 31 and have been trying to conceive since June 2020. In that time I have had 4 miscarriages (one of which on Dr Shehata’s plan)

I am currently 5 weeks pregnant (5th pregnancy) and absolutely out of my mind with worry. I’ve had on and off cramping (nothing intense) but just have a gut feeling something isn’t right. I’m knicker checking like a maniac and feel like I'm grieving this pregnancy already.

Posting today in the hope of any words of support from anyone who has experienced cramping in the early weeks of pregnancy with a positive outcome. But also posting as I really think I would benefit from sharing and chatting to others in a similar position.

Im so sorry we all find ourselves here and sending lots of positive thoughts to everyone going through this journey 💗 xxx

No major update from me but just wanted to say I'm thinking of you ladies and so sorry everyone is going through such a shit time. Its such a stress, can totally empathise with it being constantly on your mind all the time.

I've been moved onto superovulation and only got one egg this month (waste of scan/consult/injection costs!!) and waiting to see if positive but not got a good feeling.

Just ate £40 of sushi, which I now seem to do every month before its time to test, just IN CASE it's the last time. (8th month in a row and counting).

Sending love and hugs xx

@SunDance21 how are you doing today?

A weekend away sounds lovely, and I think it'll really help.

Always here, remember that 💗💗

@Onwardsandupwards1206 welcome to the thread, and congratulations to you on your pregnancy.
I don't have any experience to share that will help, but I have heard cramping can be very common, given the stretching of your uterus.

I find this place really helpful to chat and get things off my chest, so I hope we can help you in the same way 🥰

@89Hope I'm really struggling with keeping the whole thing out of my mind today, it's such a consuming thing. I'm almost sick of it to be honest.
I totally know how you feel about thinking a super ovulation cycle is a waste. So I hate myself for saying this, because I never want to hear it, but they always say you only need one! So definitely don't write it off, and you'll have timed sex perfectly! My fingers are crossed for you.
Have they increased your dose IF there's a next time?
When are you testing?

Sushi is great!! Enjoy! xxx

@VenusStarr how are you doing lovely? xx

@myrainbowjourney thanks lovely! It really is nice to have found this thread and to not feel so isolated.

@89Hope and I’m with you on the sushi! Delish!

Good luck for testing ladies xxx

@myrainbowjourney
I find it really isolating. Between this and the pandemic I've lost touch with most of my friends.
I know the feeling you have, it's such a downer after a negative :-(
Testing Sunday but not got much hope. Yes, they have upped dose to 7.5mg for next time and she said my womb lining was a bit thin (which is annoying as that's what they said in my first apt 8 months ago) so now on extra daily hormones for this but I didn't started it mid cycle so they said it may not take affect this time.
@Onwardsandupwards1206 I had cramping in my first pregnancy for weeks and was told it was normal (obviously it did go wrong in the end at week 11 but that wasn't connected). Hot water bottle helped.
@SunDance21 I had various discomfort with progesterone and after the first cycle I had to put it in the booty. Not very pleasant but no symptoms after that!!! Sending positive wishes and hugs xx

@myrainbowjourney thank you it really is appreciated ❤️

@Onwardsandupwards1206 I’m not sure if this will be a comfort to you or not considering I’m having brown spotting on every wipe, but, I am having mild cramps too. In my mind they’re normal, it’s only if they are server that it’s a problem. It’s always been explained to me that the uterus is a muscle and when something stimulates a muscle it contracts, so it’s actually a good thing in a way as it means things are happening :)

@VenusStarr how are you doing? ❤️ I hope you’re okay x
——

I’m still having brown spotting and still haven’t heard back from the clinic with a date. I’m really unimpressed to be honest. If you’re at this clinic it’s because you’ve already been through an ordeal and you’re paying for them them to help you but they’re just leaving me in limbo.

I could definitely have got myself a scan booked at EPU now but I’ve been putting it off because they said if anything happens come to them because they might be able to help… I definitely feel like a cash cow to them at the moment. If I don’t hear from them by lunch time I’m just going to go to EPU.

I’m kind of resigned to the fact I’m going to have another miscarriage and just sort of getting on with my life now. I think I’m going to take a few months off trying after this and just focus on enjoying my life with DH.

It’s so hard because part of me is like “I’m only 30 so I still have time” but equally I know the older I get the less time I have and I don’t want to waste the time at the moment. But I think it would be nice for us to have some months just enjoying being married and going out and doing things like we use to…

The only plus is I weighed myself this morning and the medication has made me feel so ill over the last few weeks I’ve lost just under a stone which I really needed to lose. I think I must be one of the only people to lose their appetite on steroids!

Going to spend the next few months focusing on losing weight and trying to get into a much better headspace I reckon. I might also try and get a referral to Coventry from the NHS.

@89Hope sorry I missed your message. That’s a lot of sushi! 😂

I am totally with you on the feelings of isolation. I think it’s been a really hard few years. Try not to be so hard on yourself ❤️

I know how all consuming this is, but try to arrange somethings to do which will take your mind off of it. Text some of your old friends and see if they’re free for coffee or dinner. Maybe have some over for a dinner party?

I know it’s not the same, but we’re always here for you ❤️

@SunDance21 do you email or call the clinic? I always email them for my appointments, send to both the office and nurses, and I usually get a reply really quickly. I really hope you hear from them soon, as you are paying a lot of money to be a patient of theirs.

To be honest, I'd go to EPU anyway, it won't hurt or change your treatment with CRP. It's nice you can double up and get the scans when you need them.

I've said the same about after this next cycle. I'm not booking anything for the what if's and it's all just taking over. If the next one fails, unless he strongly advises to keep momentum, I'm going to take a little break, get some trips and nice things booked in. Life is on hold and it could be forever! It's such a shame to not be enjoying time.

I really hope you're proven wrong and your little embryo is just nestling right in. I'm keeping positive for you, I know it's not easy to do when you're in the depths of it.

30 is young, but I know me saying that doesn't change how you'll feel. I'm 36 and feel like a ticking time bomb. My friends just had their baby at 39, so I need to remind myself there actually is still time. It's just not how I imagined it xxx

I’ve done both. I know they’re really busy, but I sort of feel like that’s not my problem… as horrible as it sounds… I feel like with treatment like this they should always be keeping emergency appointments available for people who are bleeding or having signs of a potential miscarriage.

Yeah I think I will. Thanks for the advice. I’ll call EPU later.

Yeah I know 30 is young.. I’m just not sure how many times I can go through a MC… when I read the stories of the people who go through 16+, I’m just not sure I can be one of them…. So I think I’d prefer to get myself into a happier mindset before trying again.

Thank you, it’s nice to know someone is positive for me! 😊 I really appreciate this group. I hope it helps others too ❤️

When I was in the clinic having my intrilipid I was talking to a woman who was 16 weeks and she was 41, so 36 is also definitely not too late, but I can totally understand why you feel the way you do ❤️

@SunDance21 absolutely agree. It's concerning to think that if I ever get pregnant then it'll be hard to contact them. I don't think I'd take to that too well, especially if I was feeling anxious. I'd expect them to be on hand for sure.

I also agree with how much you can deal with. I remember my nhs consultant said to me to keep trying, because someone had once had 12 or so miscarriages and then had a baby. I remember sitting there and thinking that wasn't going to be me. There's also only so much someone can take. I can't go through that much sadness and heartbreak.

I think it's just so easy to forget who you are as people. I think I have. Can't go out and have a drink, can't book a holiday in case you might need an appointment in that time. I think it's very isolating and I feel like I've lost touch with some friends too, because it's too difficult to just join in. Sad really.

I do keep reminding myself that 36 isn't too old for this to happen for us. I think if someone could tell me it WILL happen when you are 39 (or whatever), I'd just relax. But it's the unknown and thought it'll never happen.

Ugh, how nice it would be to just have sex, get pregnant and have a baby at the end of it

@SunDance21 thank you! What you said about the uterus being a muscle and contracting makes sense to me, so that definitely offers a bit of comfort - thank you. I’m sorry to hear you’re still having some spotting, I totally understand why you wouldn’t be feeling optimistic. I think it’s a bit of a defence mechanism as well to assume the worst to protect yourself from more disappointment. I definitely do that. Expect the worst and then I feel prepared. Hopefully you can get seen today at the EPU. Keeping everything crossed for you xx

I have the same concerns about age, not so much on a biological level but more just getting left behind in all my social circles. I’m running out of childless friends and I definitely find it difficult being around pregnant friends or friends with newborns 😞

I think taking some time out can be really beneficial, we had 9 months off trying last year and it was really lovely to feel like me again after being pregnant 3 times in the 6 months prior!!

Hi ladies, I’ve been reading the thread for a while and crossing everything for you all. I stared with Dr S in early Dec and now on my 3rd super ov round. I had 2 mcs last year and went to see him after another specialist diagnosed blood clotting/ dismisses slur on/ NKC then I had my second loss so I lost faith in that, Dr S tested and found v high NKC. Fingers crossed for all of us soon.Your posts have been so useful - thank you for sharing. I completely sympathise with the feelings of being overwhelmed and so so sad it’s not just an easy journey as it seems to be for so many. I have a few questions on the super ov programme and wondered what you thought.
I’m super exhausted by 9 in the eve. Do you get this? Also been feeling so low I’m on antidepressants - all cleared as ok with the programme drugs. I stated without but felt so so awful/ depressed and taking them is the only thing helping. Also what fo you think about exercise? I went to yoga recentky but read you shouldn’t do that around ivf transfer time so wondered if the same applies. It helps my anxiety but I’m so worried about doing anything that hinders things given all the drugs and herbal things I’m on too.
Does anyone believe in herbal things to help ie Maca, pollen etc?? Thank you. I’ve done so much over the last year diet wise etc but you start doubting your own sanity sometimes!! Thank you 🌹 🌹