PCOS TTC Metformin and Letrozole - what are your experiences?

[Leah89]

Hello everyone! First time poster so pls be gentle lol!

I have PCOS and have been TTC for 2 years. I am overweight and have typical PCOS symptoms - I am lucky if I have a period once a year!

I have started Provera 5mg for 5 days (to induce an initial 'period'), 1000mg Metformin, Letrozole 7.5mg (CD 2-6), Vitamin D3 4000iu (very, very low in this - daily high dose until it returns to normal levels), Folic Acid 400mg and a Multivitamin. I have a blood test on day 21 and day 28 of my cycle to test Progesterone levels.

Are there other ladies TTC in a similar position? How are you finding Metformin and Letrozole? Do you have any success stories to share?

Thanks in advance! xxx

Bump x

Hey iv been given provera and letrozole a few months but haven't started it yet are they still taking blood tests for this with the pandemic going on am gonna start them the end of the month xx

Hey @Leah89 how's it going? I'm on metformin and i'm 3 days into my provera prescription. So hoping to start taking letrozole next time. Did you have any side effects? My consultant mentioned OHSS as a slight possibility if you have PCOS and are taking letrozole. Did you have any issues with that?

Hi Leah, i have just come across your post. Did you have any success. I too am overweight and have pcos. I have periods but my consultant has come to the conclusion that i don't ovulate. We tried clomid with regular scans and progesterone tests but this hasnt worked. I am now starting letrozole along side metformin which my NHS consultant suggested may hwlp with the fact i struggle to lose weight. I went private as i was waiting so long with nhs. Im glad i did as ive been told on my bmi they cant help.

Any advice would be appreciated xx