Immune /natural killer cell treatment when ttc or pregnant (aka the 16th pred thread!)

[sunnyday01]

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

Oh trying, I'm so sorry that they have gone down. Thinking of you and look after yourself xx

Oh Trying i m so so sorry. That s so unfair, life is just so shitty sometimes. I really hope you are as ok as you can be. Sending u the biggest cyber hug.

Am so sorry trying!! Like hula said I never understand why life does this it's so cruel! Thinking of you and DH! Hugs xxx

Trying - so sorry, gutted for you. Really thought this was it. Don't give up though.. Everything is lined up for success now, it's just a lottery with which will make it but fingers crossed this year is a lucky year overall. Sorry you're going through this now though - it's just not fair- especially after all you've been through. Bug hug xx

Big hug even ! Xx

Oh trying, so so sad for you and your DH. Can't imagine how you're feeling. We're here whenever you need support. Please take care of yourself x

Thanks for ur words. Life is shit, what can u do. Ur right, let's hope it's a numbers game just when is it my turn? And all of u other lovely ladies.

At least I have my wonderful DH even If we have about ten sperm left and I'm not sure on our chances of a bfp are let alone a miscarriage again.

Booked appt at argc in London. Think that's my next port of call.

Wine and chocolate and my lovely DH for next few days
Xxx

Yes most of us are blessed I think more than others with Super-DHs. It's thee most important thing. I really wish, hope and pray we are all blessed in every way too though.
Take care xx

So so sorry Trying. I can completely relate as you know... Have had an almost identical 4th mc just a few weeks ago :( It sounds it'll happen naturally though and you won't need a d&c.... Hope you have comforting cuddles from your hubby & that you can both look ahead with hope in your hearts xx

Yes wonderful DH's. Feel so bad he's so kind and lovely and I wish I could give him a little one :(

Got mine booked tmrw, I never miscarry naturally and ive had failed natural and medical management before and the whole process gets dragged out. Absolutely can't be bothered with that this time so just want it over.

I've joined the gym and ive registered with the argc today. I've booked flights to see a friend in Spain for a weeken when DH was at a course. I'm going to get fit and pray and hope its next time or the time after. I'll prob go into it with PGD incase it is chromosomal although I doubt it.

Hope everyone else doing ok? Bit shit on the thread recently after some wonderful news. Let's
Hope it picks up xxx

Aw trying, good you ve made a plan.
Sounds sensible to have the dnc rather than wait. Will you have testing to see if it was a chromosal issue ? At least with ivf you ve got the PGD option next time. Will you be able to get any bits of your argc cycle on the nhs ? (I m guessing they are particularily expensive). I hope tomorrow goes as smoothly as possible, will be thinking of you.

Trying I am so sorry.
Thinking of you today

Hi hula. Thanks sw.
God it's awful when u wake up and rem isn't it. I thought this one might work as it was my first on the drugs.

Like u DRtCC I seem to be loosing them early. I reckon I prob only made it to 4.5 weeks , same as my last one. For some reason my second made it to 9 though? No pattern...and the first 6. Either way the time is getting less not sure if this bodes well?

Yes I'm going to stress how imp the karotype is, d and c this afternoon. I can't believe 4 miscarriages aged 28-31 can all be chromosomal. And it's annoying not knowing and wondering. I wish I had done PGd this time, I'm annoyed I didn't push for it.

Argc is like 15 grand with full immunes :( . wont get it on nhs I live up North and just had my one nhs cycle. (Which cost 4 grand !???)

I feel like maybe it's too drastic and I really dont fancy uprooting my life to london. But with DH sperm while i its dissapering we have to act while he's still making some fresh stuff. If I spend another year trying 2 more cycles here and then in a years time he makes zero fresh sperm? The frozen stuff we are saving up doesn't always defrost well, although I'm grateful we are saving it and realised at this stage what's going on (weekly wanks at clinic, poor Dh).

I think our urology appt will be the most imp, the chap is kinda the shehata of the low sperm world! I suppose he will be best in guiding us how quickly we need to act. He may have some tx that may improve things etc

If there was no sperm issue I would just use up my 3 blastocsysts here first.....
But on the other hand it means uprooting my life and taking time off work as they do daily bloods during stimming and when u get pregnant....there's a lady on the RM thread who has had a natural preg and gone to them for their monitoring and drugs maybe I'll drop her a line... I don't really fancy turning my life upside down. But maybe I need to?

Xxx

My Dh is convinced it's his sperm causing the issue now. Dna fragmention, Ros tests on sperm and sperm anueploidy seems to be the sort of things we need to look into. How did things get so complex?! I'm sure it's not meant to be this hard? And am I looking for answers that are not there? Is it just bad luck and I'll be fine next time with no Tx?! Not sure I want to take risk to be fair!

Thinking of you trying!! sounds like you are doing the right thing and getting appointments and trips booked to keep moving forward and keep busy. You are being so incredibly strong! I've no idea why some of us are placed on this journey...maybe we are the strong ones but I really do believe we will all get there someway or how! It just takes a lot of perseverance and bravery!!! You DH sounds like an amazing man...I hope you two can take comfort in how special you two are together whilst going through such a crappy time! Love and hugs and hope today goes ok xxx

Thanks determined. I do feel so lucky to have him. He's been kind supportive loving and caring. And also practical and descisive. He hasn't been a guy about his sperm count like I would have thought and just supported me through the ivf and didn't bring it up. I've started wondering if maybe the greater beings that exist think I should be happy with just him and shouldn't ask for more as im already lucky to have him. But he says life doesn't work like that! It's not one or the other!
How r u lovely? Are u waiting for ur retest, going to take a leaf about ur book and break from TtC after this weekend and just take a step back from thinking of it all. I need to loose this pred weight and enjoy life and start thinking again in a few months.
Ps of I end up at argc they use ivig

Ahhh I want to give you both a big fat virtual hug! It sounds like the two of you are making each other stronger through this and that's so special!

Yeah, test was done yesterday...got to be honest that last few days i have had zero sleep and mega stress with work so my NK cells were probably mental!

I really tried my best to tell myself i didn't have any (NK cells) and the drugs were working this time but we will see (mind over matter eh). I get my results next week so that's it, nothing more to be done but face the music of whatever we need to do on this TTC journey...(if we decide to do it of course).

I really really really advise the break...i am in such a better place mentally i am happier and positive and actually look forward to things and enjoy them when i do them. I was so depressed at the beginning on the year and i think so was (or it was deffo impacting) DH. I am fitter, stronger, I smile, I laugh...(i don't cry all the time). I am like a different person and i feel ready to deal with whatever life throws at me again...but with a lot more wisdom and reflection! Sounds a bit deep but it is amazing what a few months and a bit of acceptance and dealing with it can do. I really think it will do you the world of good to get your mind and your body primed. Its been through a lot!

I really hope today is a quick and easy as it possibly can be xxx

Thanks. I think that's what I need. I need to get fit, enjoy life, see my friends, get my confidence back and then in 2/3 months be a more relaxed person. This whole thing consumes your life. Also I have a personality where I can't stop reading researching looking for answers and trying to understand. I need to switch it off so my brain rests. Will try counselling to help me with that I think.

Fingers crossed for ur results, u sound like ur in the best possible place u could be in and I sincerely hope next time is ur time. Either way, at least u have you back. That's the most important.

Thanks Trying...I'm as positive as can be!

Oh the researching...that has been my biggest issue I was obsessed...if Only I could find the miracle answer, and you know what, I've never found the answer...and I won't because it doesn't actually exist (per se) it took my hypno lady to make me realise (I ignored my parents advice on that one) I was just exhausting myself, as soon as I stopped things started to change. I still waive at times but it's to a minimum. When you are ready to stop it trust me things will change and you will feel better xx

Just had scan. Nothing in my uterus, well it's just an irregular lining. So nothing to do surgery on. Need a few hcg to check levels falling , chance of ectopic unlikely based on scans and results.
Will escape a d and c possibly, that would be a small lining.
So must have lost it v early and it's just been reabsorbing itself.

Drtcc could I let
Me know how supplements ur reserch has led u to?! I'm not doing any more reserch so will just ur wonderful judgement :)
Thanks
All have a lovely sunny weekend xxx

Trying, good that you may not need a d&c as you say a slight silver lining. Hope you're doing ok, you sound like you have a plan - I always feel better when I have a plan!

I'm 12 weeks tomorrow if i go by my dates and 11 weeks today by my scan measurements from Mr s - so close to that first hurdle! I have my scan on Wednesday at local hospital - getting really scared again now - although I have had 2 good scans I can't help but worry that something may happen/ has happened in past couple of weeks. I think once I'm past the scan I'm going to get a Doppler to help put my mind at ease.

Trying - thinking of you and really hoping your impressive strength sees you through as well as can be expected. Your plan to recharge first sounds really sensible and good. I still have a positive feeling about your future - yes you've challenges, but you've so much going for you and people -experts and friends - behind you.
Sunny - I know that feeling .. So near yet so far.. It's terrible how much the past affects us.. But understandable. I see where you are now and feel sure you'll be fine.. But I remember a month or so ago when was in your shoes and was so nervous. To be honest I still am.. For me 20 weeks is a biggie as they didn't do a nuchal scan as had the Harmony so am worried about physical issues. I'm also worried every conscious moment about the heartbeat but have decided at the moment to avoid getting a Doppler.. I saw a midwife struggle to find the heartbeat on tues as my baby kept moving and I thought I would just give myself panic attacks if I couldn't find it. I might change my mind though but people say when you start feeling movement then that can work as well to reassure.

I hope I haven't been insensitive writing about this stage .. I can hardly believe myself how far I have come... I want so much to be the next 'Hope' and got the good luck to be infectious for everyone.
I'm really inspired by how everyone is coping - even when it seems someone isn't for a bit, it's actually a strength - dealing face on with what's happening. Anyway I'm getting a bit emotional now as I think much of the last few years have caught up with me. This forum really has been a god send and thanks for everyone's support. I might not comment as much but as I've been through and googled so much please always feel free to message me direct if you want.
Happy weekends everyone xxx

Thanks rosa - I do t think I'm going to do the harmony test, Dr s gave me details but said it wasn't a necessity given I'm under )35. Getting the nuchal done though at 12 weeks. Like you I think once I feel the baby and get past 20 weeks I will relax a little bit! My parents, especially my in-laws can't understand why I'm worried now - I don't think they will truly understand do don't bother telling them about it!

I know - I get sis in law and friends asking Qs excitedly but my head is just not there yet so it feels like they are being really insensitive /inappropriate .. But they just can't understand. They say I'm sure it will be fine etc etc you just need to relax/enjoy. Sadly as we know too well nobody can ever be sure so we just have to hope and take each day as it comes. Take care x