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Immune /natural killer cell treatment when ttc or pregnant (aka the 16th pred thread!)

992 replies

sunnyday01 · 05/06/2015 19:22

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

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Tryingno1 · 25/06/2015 08:06

Ah thanks. My place does pre ivf, 4 8 and 12 but not 16. Does he still do them in Wimbledon or does healthcare at home do them? I haven't even rung my clinic to inform them yet as was too shocked yest! I'll let them know today...

Seekingmiracles · 25/06/2015 08:26

Yay!! More brilliant news Trying!! I'm so happy for you! I knew you'd get some good news... Just had a feeling!! Obviously this part is scary but as others have said just try to be positive and keep off the internet.
I had intralipids via healthcare at home, very easy. I only had to have them at 6 weeks.

Determined123 · 25/06/2015 08:29

Whoop trying! Such amazing news...I am so so happy for you... THIS IS THE BEST NEWS Smile

No not ttc yet for me, still got to have a retest after 2 weeks of pred so won't be until mid end July (only started this week) that I know what the next steps...kinda wish I did this sooner but I just don't think I was ready!! I don't think I could get preg anyway...my cycles are wrecked since last mc I'm not even sure I'm ovulating?!?!?

Sorry only popping in briefly...so busy with work etc (and wedding this wknd yes which was my deadline) so it's all go!!

Hi to all xxx

Tryingno1 · 25/06/2015 08:48

Thanks guys! Eeeek. Only hurdle one though.

Determined I know the ants in the pants feeling to get going! But I think it's done u a world of good and I'm sure u will be armed with a strong plan soon! Maybe SO will be best for u as it did bring ur l phase longer?

Me and dh are off together this week which is nice. And I have lots of leave off work to take it easy and relax. My mum is already fussing over me as is DH. I keep telling them I don't feel anything yet so they can wait to fuss over me! Felt v guilty over the excess Choc and cake I ate at my bday weekend can't have been good for the bean. But yest I ate so much fruit, salad and grilled chicken And nuts and organic milk! Need to keep the sugar low as the dex is def making me feel hungry!

Seekingmiracles · 25/06/2015 09:14

I'm sure it's the birthday cake that did the trick Trying Wink! There's got to be some enjoyment in all this stress and worry and cake definitely brings enjoyment!

Hula2 · 25/06/2015 09:20

Trying that is soooooooo fantastic !!! I know its one day at a time but at least the getting pregnant hurdle is done. Great you ve got lots of time to chill. Feeling really positive for you. Afm i ve got my scan mon so hoping for some decent follicles esp as he s put me straight on the higher dose (7.5mg). Ovitrelle is in fridge waiting and last humira is done so lets hope i can pop out a good egg !

Tryingno1 · 25/06/2015 09:38

Great hula! I have it all crossed for u! U so deserve a bfp soon too! Let's hope SO gets those eggs moving!

sunnyday01 · 25/06/2015 10:40

I had healthcare at home too - all very easy - my next one is Monday all being well.

That's how I have got through it taking one day and one night at a time - it feels like it is taking ages. I haven't told anyone yet - if sat goes ok we are going to tell our parents then wait up the 12 week scan before telling other people I'll only be telling work and close friends though - won't be broadcasting it on fbook!

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Tryingno1 · 25/06/2015 10:46

Can't ever imagine doing a facebook! I'm not planning on telling anyone for as long as I can hide it! Minus my parents, best friend and dh who knew we were having Ivf.
I feel like rosa preg has gone so fast, and my 24 hours of knowing feels like an eternity!
Will u be 8 weeks on sat sunny?

Snoopysimaginaryfriend · 25/06/2015 11:07

De-lurking to say huge, ginormous congratulations to hope! A happy ending to what must have been an awfully stressful time x

And congratulations trying! So so so pleased for you! And good news about the sorry situation!

As for me I'm having good days and bad days. My period arrived yesterday exactly on schedule which I hope is a good sign for my wtf cycle that things are sorting themselves out. Now we just have to get pregnant again, I'll admit I'm very scared. What if it doesn't happen? And what if it does?

Work have found me an office job, the same office I was in before first mc, but at least the other two people in there are friends who used to be on my team. I'm hearing awful things from work, while teams getting scrapped and people forced to move. Makes me very scared for the future

Snoopysimaginaryfriend · 25/06/2015 12:19

'Sorry situation'?! My phone doesn't like the word 'sperm' haha

sunnyday01 · 25/06/2015 12:26

Plus my eating hadn't been great over past few weeks, I need to comfort eat to get me through!!

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sunnyday01 · 25/06/2015 12:29

No I'll be 10 weeks on Saturday - I'm struggling to hide it - my clothes are snugger due to eating more and feeling bloated

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Drttc · 25/06/2015 12:56

Wow loads to catch up on!

Trying, congratulations!! It's been a long wait for you and you really deserve this. I know it's a tough wait these first few weeks, but so far this ivf process has been very positive for you. You've got embies and spermies in the bank, so now it's time to relax a bit. Everything that can be done, has been done. A few weeks from now you may be settling in to the idea and feeling much more confident :) So cool that ivf worked the first time too!

Glad to hear everyone is doing well! Good luck with your scan Sunny! Not far from that 12 weeks mark now :)

Aww snoopy I'm sorry you're worried about so many things. Would finding some positive distractions help? Country walk at the weekend, romantic date night with lots of wine, picking up some good books?

I'm plodding along. Debating whether to DTD or not as I'm now cycle day 10. I know people have said not to but I just feel with hyper fertility I'm dealing with something a bit different. I keep thinking 'what if I miss a good egg'. The stories I hear about hyper fertile people is that they just keep trying and trying until they get the 'good one'... Some with like 10 miscarriages in a year, with the 11th BFP resulting in their rainbow. Of course if my cycle is a wtf this month then it'll be out of my hands anyway!

Tryingno1 · 25/06/2015 13:43

Hi snoopy! Thanks for ur wishes. I'm glad they have relocated u I think it will do u a world of good! It's natural to be crapping urself! But u will get preg and u have to hope in mr shehata Tx. Like drtcc says, spoil ursrlf enjoy the time u have with ur dh and get strong and ready for next time. (My journey leading to ivf is a really odd one given my past pregnancies - testicalar failure is another 1 percent statistic like RM so don't let that scare u into thinking u may struggle to Get pregnant) .

Sunny i comfort ate all through ivf! I was good with high protien which is what they advise but had cake or icecream nearly every other day! I usually weigh myself weekly and try be good when I see a pound or has crept on (I have to work hard to keep My bmi In check as I love food!) but I just can't deal with weight stress too at the moment ! So for the first time it's been a month since I weighed myself and my jeans felt tight today :(. But who cares! Small price to pay! Just hope midwife doesn't tell me off!
10 weeks!!! How did that happen! So pleased for u, they say if u have good 10 week scan ur more or less home dry (obviously panic never leaves). What time is it I'll be refreshing the page waitjng for ur news! Have u had ur midwife appt?

Drttc, I know the feeling of wanting to get on with it. But if u are hyper fertile u will just catch the month later rather than risking a bad egg in the wtf? I know of a few consultants who really think u should wait a month before ttc again. at ur age u can't have that many bad eggs, ur young and healthy. Interestingly out of my 6 embryos 2 were def duff as they died by day 6. The other 4 scored low in being chromosomal (but can't be sure,it's just guess work). We are similar age too? Have u got an appt with mr s to discuss wot to do next time as he sometimes tweaks things?

Drttc · 25/06/2015 13:53

Hey Trying! I've read a lot but how can a miscarriage result in a bad egg the following month? Aren't your eggs already there before the miscarriage?

I'm going with the idea that the 'non fussy uterus' is allowing bad eggs to implant. So if I had a bad egg last month, I'm hoping I may have a good one this month. So if I skip this month, I lose my odds if that makes sense. I can't help but think 3 miscarriages in 6 months suggests more dodgy eggs than normal? This months pregnancy never had good hcg levels, which indicates the embryo wasn't dividing (growing) properly. That's why I'm convinced it wasn't a good egg...

Drttc · 25/06/2015 13:54

Oh and yes I'm 29 in September!

Drttc · 25/06/2015 14:02

And I was only able to get an appointment with Dr S for July 20th :( ages away!

Tryingno1 · 25/06/2015 15:30

I'm 31! Not very fun! Haha. Yeah I know, it's hard to make sense of it!!
my family member who is an Obs and gynae consultant says 2 months break as the lining needs time, ur body needs time and ur hormones need time to back to nornal and relax. Ivf failure is also 2-3 months to give ur body time to settle obv that's different but I suppose it's same line? Mr s says it due to bad egg I think (from what he told determined) But to be honest the reserch suggests otherwise- and there was a huge study on Scotland showing if u got preg within 6
Months u were more likely to have a notmal preg and also less complications in delivery etc. U have prob read it.
I'm sure us lot are a complicated lot-I see a lot of us having c sections, early labour etc. Just like hope with her placenta issue. We must be made diff! As long as we get there I suppose.
Do what makes u feel comfortable! There are plenty of women millions who concieve in the wtf and are fine. I think determined said her mum was!! So if u r ready and u have made a choice (well balanced as u have a brain!) then go for it! As long as u are happy :). I really teally really hope that ur next bfp is sticky and hopefully it will be. I rem talking of 10/11 miscarriages when we used to get preg quickly too. But I don't think its that common. In fact if u look it up 1 in 100 have 3 in row and then 4/5/6 etc get v v v rare and eventually it just HAs to be ur turn! It just has to!

Drttc · 25/06/2015 16:18

Thanks Trying! I agree that your body would need time to get back to normal after a miscarriage. But mine end at such an early stage that I'm not convinced I would have the same issue as someone who had one at say 8,9,10 weeks along. Even though I was technically 6 weeks my hcg level was that of someone who was 4 weeks pregnant (just after you miss your period). My womb was completely empty :( Also, Dr S looked at my womb lining the cycle after my previous miscarriage and said it looked 'lovely'. So I think waiting 2-3 months when I'm having repeated chemicals wouldn't do much... I've had 4 now, and 3 of those happened after breaks of anywhere from years to minimum 3 months. So, waiting hasn't worked out for me.

That said, my body may not cooperate this month (as we know all the pred can make things weird)... So it could be out of my hands. I feel like, I've tried what everyone has told me and now I've had 4 it's a desperate times. The scientist in me (I do research) feels like I need to test this 'find the good egg' theory.

Sorry to go on and on! Thinking out loud. Very open to everything everyone has to say. It's just in my nature to overthink every thing haha

Tryingno1 · 25/06/2015 17:09

Of course this is what this board is for. I've millions of times rambled on!
Ur a empowered intelligent young woman, u should do wotever makes u comfortable and happy. It is hard to make that descion but it sounds like u feel confident with the one u made? Are ur nk cells v high? I can't rem sorry! I think being in the feild of med/reserch is a blessing and a curse!

Tryingno1 · 25/06/2015 17:27

Ps 4 miscarrages in such a short time is just rough :( and unfair. Im so sorry :(

Drttc · 25/06/2015 17:49

It's so exhausting having to make these decisions. I tend to think it to death, make a plan, then go on autopilot following whatever plan I've made.

Yes, they're very high NK! How are yours? Are you planning on seeing Dr S pre or post scan?

Drttc · 25/06/2015 17:51

Well I my first miscarriage was two years ago, then 3 this year (jan, feb, June). Mental to have had 3 this year I know :(

Tryingno1 · 25/06/2015 18:01

I had my first 3 in a year too. June sept and last June. Was tough going. I wish it hadn't taken so long to get preg but I'm sure im feeling calmer this time as some
Of the pain has settled. Plus I'm in total denial mode. I don't even want a scan! Last time I wanted one every day literally! It was a private scan I booked which confirmed my
Misscariage.
Mine are normal levels but slightly hyper! So not very high. The ivf place seem To have picked up some even more controversial clotting issues so maybe they are playing a role. To be fair I don't know! As long as one of these drugs works...