Immune/natural killer cell treatment when TTC or pregnant (aka the 14th pred thread)

[sunnyday01]

Continuing from 13th thread

Thanks girls. I ve never had implantation bleed or mid cycle ov spotting before and seems more than that (unfortunatly!). Just gonna have to wait it out and hope this is a temp problem. Maybe i ll just have to take it from bfp if i manage to get one....

ugh! girl at work who just got married was talking to me about hols, and she said 'well i hope to be pregnant by august so i want to choose somewhere not too far away' etc etc - oh only to have that hope when first starting out again! But also - its my turn next - i've been waiting longer!

Oh sunny! I know ur pain. I had a girl complaining to me the other day saying "I'm preg it took me a whole year " a whole year can u believe its been awful and stressful Etc etc. little did she know what I've been through. I just nodded and kept saying but the baby is fine and ur 13 weeks and congrats!
And yes we are all next on here. But doesn't work like that :(
I'm so not looking fwd to seeing my sil , luckily she drives my DH a bit mad too but seeing her bump and little one knowing I've new trying for the same amount of time. NOT FAIR

Sunny and trying know them feelings well! Sometimes you want to scream and shout and other times you think actually I am too above it!
My sil is same position 2 in the time we have been trying. First when we found our dp sperm was lower than normal and lazy she said what a relief at least it's not you! WTF?! Either of is isn't good! Then when found nk cells issue too she said hurt up they are waiting for a cousin ! Erm yes well I would but clearly 3 and a half years on it isn't the bloody easy for us all! Rage! I get rage every time I hear idiots say stuff like this! X

Ur sil sounds like a douche dildoos!

Determined hope ur holding up ok

Hula what happened to ur bleeding? Unusual that happ and after 1 course of pred too....

How funny I have one like that too!!

It's so hard having to behave normal when others talk about their pregs when it was such a breeze (don't moan to be about getting fat when you know I am ttc and on strong fat enhancing steroids...that kind of thing!)

Thanks trying - being honest I am not holding it together at all. Completely broke down night before last and last night as I think all is lost again. Boob soreness completely gone and feel absolutely nothing! I am just devastated that this keeps happening (and 2nd on treatment). :(

Oh dear I'm sorry determined. It doesn't help all of us saying "it might be ok" but it might??? Ur not spotting and the pred 100 percent mAsks symtpoms - it used to be used as morning sickness control years ago and was v effective!
Have u got a scan planned for when u come back? If anything so u can be happy or stop taking the pred? I truely hope ur just being a worry wart! No spotting is good. No crAmps also good.

I'm feeling a bit hopeless again this am. If it takes me forever to get preg, then I miscarry again and this cycle continues I'll be 40 and nowhere closer. I'm already loosing. Bit of my mind, I'll have totally lost it by then! Don't think DH will be very impressed about getting his sperm checked ill have to force him into the surgery! What's up with men and their sperm?! Well mine Anywys.

Thanks trying...I know it ain't over till it's over and thing fluctuate but I was naughty and did a test, the line was lighter and slower to come up (didn't go dark enough for the hook effect ha ha ;))

I wil book an appointment for after hols to quiz Dr S about next steps. I get no further on or off treatment so it's madness to continue in the same way. I have spent over £1000 on intralipids these past few months, meds and trips to london not to mention the time out my brain has had from my normal life...need me/my life back!!

Try not to lose your mind (even though I have ;)) you will get there... We all will and when we do it will be so amazing!! So deserved!!

Ha ha you may have to trick DH to the docs or give him the guilt trip about all you have to do...I do that all the time in a jokey way

Xxx

Mr s has a drug called hydroxychloroquine he gives to women who fail on 2 goes of pred. Ask him about that. But we still don't know it's failed-except I'm sorry line is lighter :( ....are u on metformin too coz ur pcos?

It's so shit!!! Aghhhhh!!!!! I'm sorry determined but u r right we will get there . Just got to keep going to block out negative thoughts and energy and SIL's!

Weird!! I was literally just talking to my MIL about Hydroxychoroquine 2 seconds ago...I just want to see what he says and am open to what he things it is/we can try...and yes am on metformin still. Will be on that for good but I am used to it now. (DH and I are considering going to a PCOS expert as could but that but normally PCOS'rs have issues getting preg although they do have a higher mis rate.

Yes you are right! Got to keep going :) xxxx

I take hydroxy already and no failed pred yet- think it's because I've high NK and high activity etc
It doesn't seem to have side effects so be worth discussing.

Hi rosa how r u? Did u decide re acu or SO?

Thanks Rosa, am booked to see him as soon as I am back from hols so will have plenty of Q's for him! Am going to check my levels when I get home as from memory I was only borderline but I think activity may be high? Am I right in thinking you have thyroid antibodies also? (or am I confusing you with someone else). Do you get given anything for that (or just pred) as I have read a few women with thyroid antibodies get given things like synthyroid and levothyroxine but when asked I got told the pred was enough (brain is working overtime as you can imagine).

Hope you are ok and have a nice weekend planned!

Hi all
Trying - decided on accu only this month as feeling too emotional to go through the rest. Maybe next month.
Determined - yes have thyroid antibodies too. I've lowered my TSH with levothyroxine and the antibodies are treated with pred etc I believe.
Happy weekend everyone x

I hope the acu works something for u. I'm just finishing af and into cycle 7. Bordeom of trying to get preg constantly for 2 years doesn't quite explain it

I'm 3 years but 5th cycle this time. Trying, I know.. It's very, very hard. Big hug. Keep smiling - and try to stay busy with friends. X

Hi Girls,

Sorry to hear your test was lighter Determined - this is such a hard path to tread, i think i ll be a nervous wreck if i manage to get another bfp. I guess as trying said if you re not bleeding or cramping then there s some hope but i totally understand that feeling of dread and limbo that somethings wrong. I hope you can know one way or another soon.

Trying - my bleeding has turned out like a pretty usual af so basically one round of pred caused me to have a 12 day cycle !! ( didn t know the body was capable of doing something so wacky as that). So i m just gonna see what happens now and pray it goes back to normal then think about whether i try pred again, haven t manage to speak to Louise yet.

Hi Rosa - fingers crossed for the acu.

Sunny and dil - sorry about the SILs you just don t need people like that around.

Sorry for the lighter line determind
The appointment can't come soon enough I bet!
Rosa- fx for your month ahead.
Trying - it is a rollarvoaster ride this TTC lark , go you find af to ovulation boring,dull them TTC to af the best part?

Hula hoping you have a normal cycle this month. Where abouts are you at the moment?
I just try avoid sil as much as possible around AF times I usually cope by focussing on the little ones as they are innocent in all that is said .
I am on day 9 today, trying smep again so last night dp remembered it was day at and stimulated dtd without being told and this meant the world so let's see if continues.
I have made the big decision that if it doesn't happen this year we have to stop trying , no more research, no more pill popping , we will move on as feel so much is on hold. Big decision but felt it needed making. That will be almost 5 years TTC and think for me that's long enough mentally.
X

Thanks Rosa, as part of my follow up and going to get some more tests done/redone. Dr S said to get my thyroid checked annually so it would be good to see where we are at and to see if there has been any diff after all these meds, diets and lifestyle changes!!

Hula am so sorry about the crazy cycle am hoping that you just needed a little 'reset' and now you are back on track.

Dildoos good luck for this cycle it's sad to be there but with the whole deadline/decision thing (with whatever in life not just baby's) it does give you that release iykwim. I haven't been on this journey as long but already feel I have 'lost' myself, my confidence, or have much fun...it's just taken over everything even when we say it won't (it has).

We are going to see what Dr S says when I am back from hols and push to be referred for some more tests (for example I have pcos but never had testerone levels checked), karyotype needs to be done (think its odd coincidence all miscarriages end at same time!!) and I have already spoken with serum about infections testing etc. I know I have had relatively few/short journey compared to many women in this immune/miscarriage journey but feel pretty broken right now! (Am sure I'll be fine once this next bit is over)!

Hope you all have nice weekends planned x

Hula-that is nuts. 12 days?! I'm sorry that happened,how disheartening u must be v sensitive to the pred. I hope this cycle behaves!

Dildoos-That's wonderful DH rem! Mine is supportive but leaves all that to me. I hope u feel peace with coming To that descion-I'm hopeful u will get preg this year though (we have only just begun the year) . But if not, I'm sure u will make the right choice together that works for u and enjoy Eachother and ur lovely daughter. It's such a consuming journey we r on. It's affects every single part of our lives in ways others can't imagine.

Dildoos-I can tell u r in overdrive. Looking up everything searching for an answer. It's exhausting. I've done that after each miscarriage. I've read like 100000 journals. Your right this whole situation takes over ur life. It's affected my sex life, my relationship with preg women and my SIL, my work massively, my weight (!), my holidays as I refuse to fly if I'm preg so can only go last minute, my bank account!! It's made me and DH stronger which is maybe the only postive. He's seen sides of me I didn't even know I had and he's loved me and held me through them all. I've cried so much this last 2 years I didn't know it was possible to cry so much. And when I'm sad I feel consumed by grief and don't see a way out and tell myself I'll be childless and run away to New Zealand!!

But.......when I'm more rational, I rem this our journey. And yes it's pants but if we want to we can get there in the end. It will be worth it and will hopefully
Make us more wonderful mummies! (Although a little jaded!)

Dildoos have u seen a rmc nhs? They will do ur karotype just ring them. Mine did mine ow its 500 quid!

Also I've done a lot of reading about weight and it def plays a role for overweight and obese. I'm straddling a bmi of 25 so my
Diet is in full force and going well. Something for us to control I suppose?

Do you mean determined? Yes just before xmas and they declined the test, said only solution for it was to get divorced!!

Trying am also reading a book on immunity and diet etc so will let you know if I glean anything!! Xx