TTC Super Ovulation part 3

[Arianrhod]

Hey ladies -

There are a few of us who are ttc after mc's, however there will be ladies out there who are also ttc for the first time or second or third without success. If anyone is on, considering or had success on a super ovulation programme then do join us. How long did it take ? Did you try IUI with it.. ? Did you have PCOS?

Kicking this off and hoping some of you will join....

part 1 here:
www.mumsnet.com/Talk/conception/1385998-TTC-Super-Ovulation

Part 2 here:
www.mumsnet.com/Talk/conception/1475108-TTC-Super-Ovulation-part-2?pg=1

I did one on Weds that said 1-2 weeks. I conceived on superovulation and no one is more surprised than me. That was my 7th go in total (3 Clomid plus 4 letrozole).

Aarrgghh I just typed a whole big post and the stupid iPad lost it!

pebbles I'd be happy to go to NewLife myself, I feel very comfortable there and of course they have Mr Gafar, if it weren't for the DE lack of anonymity (and the price of course!). I'll be by interested to hear how you get on, wherever you choose.

brown I'm glad to hear your OH has agreed to try to buck his ideas up a bit. I think sometimes they just need a bit of a wake up call. I was actually going to say I wouldn't rely too heavily on those Internet cheapy tests, I know some ladies swear by them but I've never found them to be accurate for me at all. I only ever use either clearblue or first response tests, as experience for me has shown that the cheapies fluctuate too much in their responses - they just cause too much worry, you don't know if there's a problem with you or the test! Obviously YMMV but it's worth bearing in mind. Also be a bit wary of the digital tests, they are also well known for being unreliable. In fact - just step was from the tests!! Of course I know that's not possible :). Anyway, I'm really really pleased all is well, fingers crossed it carries on that way!

buzzy Interesting to hear you're going to Reprofit also for DE, I've only ever read good things about there. If you don't mind my asking, what made you choose there? I'm really ingested to hear of people's different clinic experiences.

duggs Agreed on the thread title! I still think SO was worth trying, I don't regret doing it at all. It has worked for some people, just not me! You're doing IVF again as well, is that right? Are you going back to LWC? And are you getting the embryos tested again? Hopefully since you sorted out your DH's fragmentation you should do better this time?

AFM well we have our first consultation tomorrow night, so I'm quite excited about it, although nervous as well - what if even this doesn't work? Can't think like that though. Here's a question for you ladies .. I'm due to ovulate this week, would you (if you were in my shoes, with worries abut egg quality) try naturally or avoid it given that we're going to be doing donor IVF hopefully soon? Should I give up on my eggs altogether, not run the risk of delaying doing IVF by having another possible chemical?

/waves to everyone

Step AWAY from the tests, not step was fro the tests. I really don't get on with the iPad keyboard!

Aarrgh .. and INTERESTED not ingested! sigh ....

Ari, we knew what you meant! Yes, tricky to know what to do. I would find it very difficult to avoid the call of ovulation in any circumstances. I will only be able to advise you when it's too late, once I know what's happening with my own egg situation and if it all progresses.
I am now a great believer in giving up. Both this pregnancy and the one with my DS I really thought it impossible to conceive and that I never would.
Also I love l-arginine. My DH has just confessed to me that when I gave it to him he was waking up in the night with Viagra-like effects. This was the first cycle I took it too, only from ovulation and to be honest, I'm still taking it, despite Louise telling me not to. Still taking co-enzyme q10 too and a small dose of DHEA. Am I mad?

You're not mad brown, my acupuncturist told me her DH takes l-arginine all the time because it helps him with digestion. I'm a big fan of l-arginine personally. Absolutely no harm in taking co-q10 all the time, it does a world of good for all kinds of things, OH is taking it to help with his heart. And DHEA, well I believe that stopping anything hormonal straight off would unbalance your hormones so stopping it immediately on BFP can't be a good thing, I'm sure - better to wean it off slowly, in my opinion..

ari I looked at a place for just IVF in Poland then my Slovakian friend gave me some info and called on my behalf to a clinic in Prague. I also looked at the place in Spain. I looked on FF overseas ivf forum and saw that Reprofit had good reviews and it helps to be able to talk to women who have been and had treatment and to find cycle buddies. I did look at Serum but have a 'thing' about Greece so chose Reprofit. They email back quickly and are happy to answer any questions you might have. I like good communication so there is no confusion. The FF forum is great as there is information on how to get around Brno, where to stay and eat, and things to do.
We plan to go for a week but some just go for a few days. Alot of the ladies on 10+ thread here are trying IVF too,

Well, having just come back from Poland I imagine it would be a good place for IVF; only 2 hours away and most people we met spoke excellent English and everything is so cheap compared with here, probably less than half price. And everyone we dealt with seemed very efficient and professional. Is the IVF cheaper too?
Reprofit seems a strange name: Repro-fit or Re-profit?

Looks like I'm out again. Bright pink spotting. 9 dpiui??

Thanks for the info Buzzy from what you have said and Mr S reaction to Create it has totally out me off. I guess I might as well go out with all guns blazing and do full on ivf!

Duggs I think you are right about the name change seeing as so many if us are looking to do ivf!!

Brown sorry but I must have crossed posts with you the other day as didn't see your post about your tests getting lighter. So pleased to hear that all is still ok so far. Pregnancy tests are a dangerous thing in the hands of us paranoid people!!

Ari good luck with the consultation tonight, let us know what they say.

Sorry to hear that Tilly

I just had a very interesting reply from the company who sell the very early tests I'd been using, the ones with the light lines, when I told them that the 25miu ones were giving me darker lines than theirs. This should help with mentalling!

'The sensitivity is not based on the darkness of the lines; it is how early you can test with them. A normal women has a non pregnant HCG level of around 4-5miu. Our tests are designed to pick up a pregnancy as soon as the level reaches 10miu. The lines on an early pregnancy test will show fainter as they also need to show negative at 9miu. '

Might be implantation Tillyann?

tilly Sorry to hear that you have spotting but as brown says, could it still be implantation?

So when do you plan to start IVF again pebbles, and will it be NewLife or are you still deciding? Will have you have to go for a consultation first, if you choose NewLife, or will Mr S simply pass your notes over to Mr Gafar?

brown Hmm Well that is interesting, but it doesn't really help some poor soul judge the strength of her hCG in early days, does it? If you think about it, FRER are also, what, 12 miu? And theirs most definitely do get stronger very quickly, in my experience. Call me a big old sceptic, I just don't get on with the cheapy tests (but I know many others do, it may just be me!). How are you doing today??

Tilly hope you're ok.
Bfn for me today so superovulation again!! X

Thank you all. I'm feeling rubbish, the spotting has disappeared again but bfn so not implantation I dont think. I don't know if I can do iui anymore, feel like throwing the towel in.

Tilly can I ask what took you to IUI path? I've done one and apparently unless a proven sperm or blockage issue then the success is no better than well timed intercourse?? So it may be that you don't need it an super ovulation or sex alone would do? Sorry if I've missed this further back?

So sorry you're feeling down tilly - I think we all on here understand that feeling only too well :( . I don't know anything about IUI I'm afraid, so can't offer any words of advice - duggs is the lady for that!

mel Sorry to hear of the BFN ... how many rounds of SO have you done now?

AFM ... well ... I was feeling so hopeful about doing DE IVF and now I'm not so much :( . We had our consultation with Penny from Serum last night and she was really lovely, really sounds interested in you as an individual and very helpful (given that it was 10pm her time and she was still happy to chat as long as we wanted!). Actually she couldn't have been more helpful, but what threw the spanner in the works for me was that she thinks I should have an hysteroscopy and endometrial scratch, as she feels it probable there isn't a good enough blood flow to my uterus. Bear in mind I already HAD an hysteroscopy with Mr S in August which he pronounced all fine and clear, showed me the photos which he said proved I had a good clear uterus/uterine cavity. Penny does have the results Mr S sent through of that hysteroscopy. What gives me pause for thought is what she says about possible insufficient uterine blood flow. I don't know if anyone remembers but after my 4th miscarriage my periods completely changed, from being reasonably heavy and 5 days long every month to being fairly light and no more than 3 days at best. I thought it the steroids at the time, Mr S said it was down to my hormones changing (the dreaded peri-menopause). I was surprised he said that at the time, as I didn't think you could become peri-menopausal virtually overnight, I thought your periods gradually changed. And it's been like that ever since, barely 3 days. So what if she's right? What if my uterine cavity looks fine, but doesn't have sufficient blood flow due to various miscarriages?

Now normally I would be perfectly happy to just go ahead and have the second hysteroscopy - I have no problems with the procedure - BUT it's an extra 1550? on top of the 5000? for DE IVF. I don't have that extra money, my lovely mother is already giving us £5000 which will be swallowed up by the IVF and flight costs. So I don't know what to do, and I'm feeling rather down about it now. Penny has said we'll just go ahead and do an aquascan (her usual procedure to have a look inside) and do the cycle, and that if the cycle fails then I'll need to have the hysteroscopy before cycling again - which effectively means I'll have thrown away my mum's £5000 on something that may never have worked anyway. No clue what to do now.

Oh, and OH seems to have it in his head that we'll turn the initial trip to Athens for him to do his wrigglies deposit and me to have the aquascan/get my meds into a 3-4 day holiday trip - which while a very nice idea, will cost quite a bit more. I was intending it to be a 2-day, 1-night trip out - fly out on the cheapest possible day, see Penny, get done, stay the night and fly back next day, using the metro which apparently is excellent. But he wants to fly out late evening on a Wednesday, stay 3 nights and fly back the fourth day, the Saturday - and hire a car - which is going to add ??? to the cost. I know it would be nice, but as I say we're on a very limited budget, and I just think it's too much.

Oh - a bit of info for those of you who have been treated for 'hidden' C and/or infections - Penny says they never completely clear (for women - they do in men) and says I will have to have 10 days antibiotics before ET and more following. Just a word of warning to you all, I don't know what Dr Gorgy's take on it is, but this is Serum's protocol.

Going to bang my head against a brick wall for a while ... won't help me figure out what on earth to do, but it's something to do!

One of the ladies on the FF Serum board has just offered me a ray of hope .. she suggested why not get just the scratch done on its own, without the hysteroscopy, assuming all would still be ok since the one I had done in August. She said she paid £85 to have it done here recently ... £85 I can do a whole lot more easily than 1550?, that's for sure! Now to find out where to get one done ...

Oh, I should also have said ... infections such as ureaplasma, mycoplasma, 'hidden' chlamydia also cause high NK cells; Penny said this is often why ladies with one or more of these infections often also have a high NK cell count. Which is interesting.

Ari, I would be very dubious about your need for the hysteroscopy personally. What you've described with your cycles is what happened to me instantly after having my DS: they used to be heavy and thereafter were three days only. My lining was only 6.57mm this cycle, the thinnest ever, but I still got pregnant. And if you ignore my AMH, my hormone results are still normal and not perimenopausal.
On the other hand, I do think the rummaging around at my lap and dye helped get me pregnant. So maybe the endometrial scratch alone is the way forward.
... Has anyone had either pred or hydroxy affect their eyesight? I've been on hydroxy for months without a problem but since I've been pregnant/on pred my vision has definitely been less focused. My brain is also not working properly at all when I felt really on the ball before getting pregnant/on DHEA.

Oh ari I was just reading about endo scratches - I want one! Where can u get one. Interesting info and do u know what I think with the news about the scratch alone I reckon u should take DH suggestion and make a bit more of it as it will take the edge off. I know is more £ but I really think it would be a good idea. Do u have to do 2 trips? X

And brown how r u doing ? Have y tested again? What is next step? X

Thanks brown, that's really interesting to hear what you say happened to your AF after your DS was born. Perhaps I should just stop worrying about it (yeah, right! :) ) - after all, I'm still regular as clockwork, that's not changed at all. I do find it a bit odd though that my periods didnt change after DD was born, nor after 3 miscarriages and 2 ERPCs - just after the fourth miscarriage which was only an early one.

I haven't heard of Pred affecting eyesight but I'm pretty sure I vaguely remember someone on the Pred thread recently mentioning I think it was hydroxy doing just that. I would email Loiuse and ask her if I were you.

duggs Oh yes, you can get them at quite a few places apparently. I emailed a couple today, one was New Life actually - they replied and said yes they do them, £150 (!!) but you have to be referred by a consultant. I'm not sure if Mr S would do that for me since it's for me to the do IVF somewhere else but perhaps he might. Yes I will have to do 2 trips, the second just a day trip for ET - I'm not worried about that, I'll just be on my own. I do take your point about maybe taking the edge off it but it'll end up being more £ than I can afford - OH isn't paying! We'll see, he is after all going along with this for me :)

brown How are you doing? Feeling? Are you having intralipids?

Ari I agree that just the endo scratch sounds like the best plan. I can't see what benefit an extra hysteroscopy would have when you have had one so recently? My periods were like yours barely 3 days since about mc3 but after my last (natural) one in Dec they seem to have become a bit heavier like they used to be - 5 days. Odd!

Our consultation on Friday at ZW went well, and I tested positive for a blood clotting gene mutation that is apparently a standard investigative test in the US but not routinely tested in the UK. So despite the ridiculous amount of tests we have already had it hadn't been picked up - definitely will have to use Clexane if ever get another bfp. I realise it might be helpful for all you ladies to know the name of the test so will ring ZW over the next couple of days to get its exact name - I did write it down, but incorrectly. I made the rookie error of not writing all my questions down so still have some unanswered ones. Also will have to have IVIG (gulp ££££££) as I can't have intralipids, but all being well we will start our cycle in May.

P.s Brown hydroxy can affect your eyesight - it should say on the contraindications you have to get your eyes checked if you have been on it for any length of time, so email Louise to ask her, I am sure she will put your mind at rest. Having said that when I stopped taking pred after a bfn once my vision was so bad I went to the optician for an eye test, so who knows!

Very interesting belly d - would u be able to post on the NK thread as I am sure there r some ladies on there banging away with dr s ( so to speak) that may have other issues too. Fingers crossed for you belly d x