How small can gap be between antibiotics for three year old?

[alittleteapot]

dd is on a course of fluclox - is meant to take it four hours a day on an empty stomach (which is quite tricky) - question is should I do it in waking hours i.e. 7am, 11am, 3pm and 7pm or should I be waking her in the night, e.g. 7am, 2pm, 7pm, 11pm?

Also how long AFTER food can you expect an empty stomach.

Thanks for advice...

anyone? gotta make a call now whether to give her another dose before bed or wake her later...