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Antenatal tests

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Original poster

High Hcg and Low PAPP A . High rish of Down syndrome

2 replies

AshFar · 01/09/2025 07:43

Hi Moms
I recently had my first-trimester combined screening (double marker). My results are:

  • β-hCG: 76.60 ng/mL → MoM ≈ 2.36 (elevated)
  • PAPP-A: 0.22–0.44 MoM (low)
  • NT scan: normal (1.5 mm)
  • Maternal age: 32
My doctor said my Down syndrome risk is 1:85, so they suggested amniocentesis. I also have other symptoms of possible early preeclampsia, including persistent headache Has anyone experienced similar double marker results .How did your pregnancy progress, and what steps did your doctor take? I’d really appreciate any reassurance, experiences, or advice. Thanks!
OP posts:
Tealpins · 01/09/2025 15:47

Do you not get offered NIPT before amnio? It's been a long time since I had these tests but I thought that was the process now?

Original poster
AshFar · 02/09/2025 15:43

Tealpins · 01/09/2025 15:47

Do you not get offered NIPT before amnio? It's been a long time since I had these tests but I thought that was the process now?

The doctor advised us to do amniocentesis directly since it provides a clear, accurate result rather than only a risk estimate.

OP posts:
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