I'm about to book a NIPT and stumbled across offers of including microdeletions in the panel. I'm a medical professional and on seeing this it raised my interest, initially thinking well yes if I'm going for the NIPT I may as well go for the full shebang
One coffee and some critical thinking later and there's me pondering how on earth such tests could provide a decent level of accuracy given the rarity of the conditions and likely high false positive rate.
Then I found this fascinating article www.nytimes.com/2022/01/01/upshot/pregnancy-birth-genetic-testing.html (whilst not from a scientific journal directly it does pull some info together in an accessible and credible way about how there are very high false positive rates on these tests)
I wondered if anyone has had these newer tests as part of the NIPT and what your experience was?