Silverfrog: "And please do try to pick holes in the rest of my post too."
OK. You said "If you read the judgement it seems to centre around the way children were recruited into the research study. So in some cases parents contacted him directly after hearing about him. That doesn't seem particularly unethical to me."
You seem to have spectacularly missed the point regarding ethical approval.
In medicine, you are not allowed to have a hunch, get some patients with interesting symptoms and poke around inside them to see if you can find anything interesting. If you want to do medical research you have to:
- Come up with a protocol detailing what it is you are investigating, the details of the types of patients you will be looking at (inclusion criteria) and the types of procedures you will carry out.
- This protocol is passed to the Ethics Committee who will decide whether the study is reasonable, that any tests undertaken will be useful, at minimal risk for maximum benefit etc.
- Once you have approval, you can start your investigation, according to the protocol, enrolling patients who meet the criteria laid out in the protocol.
What happened with Wakefield is that they came up with the protocol, put some children through the procedures detailed in the protocol for research purposes (as evidenced by correspondence surrounding the patients and the lack of specific clinical need for certain procedures), and only then got ethical approval for the research.
The Ethics Committee specifically said that any children investigated before 18th Dec 1996 were not to be included in the study (although they were) and the procedures that were carried out on them, that were clearly for research purposes (they followed the protocol) were done outside of a proper study, and therefore without ethical approval.
Also, children were enrolled into the study who didn't meet the specific inclusion criteria detailed within the protocol (type of vaccination), which you can't do!
"Ten years ago they were meeting standards laid down this year. And yet they were supposedly acting unethically. Maybe someone could explain it to me. "
You can't backdate ethical approval for procedures. You can't cut someone open, have a rummage around out of interest, then find out they've got cancer and try to justify the cutting open and rummaging by saying 'well, ten years later that's actually how they diagnose cancer'.
"Wakefield says btw that colonscopies were covered under a 1986 project ethics approval"
So if the colonoscopies were done for a particular piece of research, they'd have the appropriate paperwork, signed consent forms for the project...what? oh.
Clearly they were experimenting on children, running invasive tests and procedures without following the standards laid out to make the research ethical and conform to good medical practice. It doesn't matter what they found out as a result of it, they still did wrong.