To wonder if there will be any fall out from skinny jabs?

[TheLemonGuide]

Everyone I know is now suddenly very slim. Okay, im exaggerating slightly, but genuinely, most of my friends who were previously overweight are all now slim thanks to skinny jabs. I am delighted for them! It seems unbelievable to think that a jab can cure this obesity crisis, but I am so pleased my friends and a couple of family members are able to live a healthier life thanks to this.

My only slight concern is, is this something that is going to be too good to be true? Do you think there will be any long term repercussions, or are we right to just celebrate this medication as a cure for something that so many have been battling for so long?

Does a BMI outside of the obese range carry the same health risk level as one above?

I appreciate many people are in the overweight range, but surely the associated risks are much lower the smaller you originally are, and therefore it’s reasonably harder to get?

If my BMI wasn’t as high as it is, I’m not sure I could rationalise what I even needed them for.

I know one person in that range who would consider them to shift some weight she sees as unwanted and unnecessary, and she’s got an ED.

What do you mean when you say off-label prescribing is standard in UK practice? Prescribers are supposed to prescribe within the licenced indications wherever possible, and most of the time they do when prescribing for adults. They should be able to show evidence or accepted practice supporting the decision to prescribe something off-label.There is more risk when prescribing off-label as the prescriber is more liable if anything goes wrong. Voy and MedExpress have already been in trouble with the regulators over their selling of weight loss drugs, so not too sure that "massive legal and clinical teams ensuring everything follows GMC and GPhC regulations"

I’m quite stunned that as a pharmacist you don’t seem to know how regularly medication is prescribed off license. Very strange

If you are genuinely interested have a listen to The Hunger Game podcast on BBC sounds. It explains the history of WLI, how they were developed, and the research into how they work.

So what are your qualifications and how do you know exactly how often medicines are prescribed off-label for adults, particularly in primary care?

I’m not the one making claims. Nothing to see here.

So you have no relevant qualifications and actually have no idea how often medicines are prescribed off-label in primary care for adults.

An interesting conclusion.

My WLI was prescribed off licence any time I wanted to keep at a dose that wasn’t an accepted ‘maintenance dose’. That was clearly stated when my order was accepted.

Have you not been informed or informed yourself of some of the serious adverse effects manufacturers have listed with these drugs?

I agree with Silence. At a high BMI, the risks are offset by the vast benefits. At your BMI, it is reckless, to my mind, to breeze over the potential for longterm damage for the sake of losing a few pounds.

You could go blind. You could develop a bowel blockage, and require a colostomy bag lifelong. You could irreversibly damage your GI tract and live in constant discomfort. Have you not bothered to look into what the risks are, or even read the thread, where people have mentioned multiple times the obvious adverse effects - all of which are known to the manufacturers, and more of which are being observed in studies.

It's a lot weirder that you are a pharmacist and seem unaware of off-licence prescribing. The other poster said "regularly" - why would she need to be more specific than that?!

Nowhere have I said that off licence prescribing never occurs.

Nowhere have I said that you said off-licence prescribing never occurs.

I guess people are willing to take all sorts of risks to feel and look better. Probably will be fall out, there is with everything.

People die for butt lifts, I can’t even see my own butt most of the time

If they want to take the risk it’s up to them and I guess there is a health benefit at least unlike Botox/butt lifts.

I wouldn’t take it due to previous eating disorder and I think it will lead to issues in some but everyone’s different and has there own baggage and priorities.

i think overskinny will become unfashionable though
As an earring disorder recoverer, I used to want to be 7 stone and now looking at Ozempic Celebs, and I am grateful I got “better” and focused on health and nutrition instead.

Hopefully for most it will be a helping hand to doing things the healthy way and a step on the ladder in learning and nutrition and exercise

did you mean 'eating disorder"?

It’s not just about “feeling” and “looking” better.

It’s also about reversing obesity and the huge health risks, pain, damage to joints etc that comes with that.

MedExpress is notoriously risk averse, they don’t even do maintenance, so the fact fhey prescribe af bmi 25 says they are absolutely sure there will be no issue with them doing so and have sought guidance from the regulators,

I think a lot of people gate keep these drugs, it’s odd, even people not on them, and feel their uneducated opinion actually carries weight, it doesn’t, what carries weight is the trial and real life data, and these are incredibly safe drugs, there are over 50 million on them globally and the benefits to society are enormous.

im on them started at bmi 32, now been bmi 20 for well over a year, maintaning on a low dose, and my health has never been better.

I suspect the issue here is its weight, women and weight. And a lot of women not on the drugs take real issue with them and want to gate keep them. And that wont go away until they can get their hands on the drugs themselves.

I’m not on them and don’t want to get my hands on them.

But I do think that whilst they may have benefits for managing obesity and the complications that come with it, there’s absolutely no reason for it to be available at a starting BMI of 25.

You’re not obese at BMI 25, you don’t have the complications, you’re at the very edge of overweight and could lose a few lbs to get back under it.

It’s not gatekeeping, it’s marketed as a weight management tool, to help manage the “obesity crisis,” and I don’t see what you need it for if you’ve never been in that crisis?

If you’ve managed to stay healthy or just overweight for your whole life, you can manage your weight without WLI.

MedExpress is notoriously risk averse, they don’t even do maintenance, so the fact fhey prescribe af bmi 25 says they are absolutely sure there will be no issue with them doing so and have sought guidance from the regulators,

What are you talking about? It might only be a small percentage of users, but there are already known "issues" with them. There are hundreds of people with lifelong injuries, and a few associated deaths. The manufacturers are making billions in profits and will just suck up the massive payouts of lawsuits as and when.

Did the poster mean 'eating disorder' when she wrote 'eating disorder'?!

The poster accidentally wrote earning disorder on the second paragraph. But its obvious what she meant. But that poster felt the need to point it out 🙄

actually no it wasn't "earning disorder" It was "earring disorder" As the vagus nerve runs through the ear and affects appetite, I did wonder if this was a genuine disability

But and I mean this politely, no one cares what you think other than a few who agree with you, it makes no difference in th4 real world. The global healthy authorities and regulators disagree with you and their voice is what counts,

feel free to write to them and explain your issues, let us know how that goes for you,

Well unless the global health regulators are on MN, there’s probably no point discussing anyone else’s opinion on WLI?

Better close the dedicated board down!

Do you know why someone who had never been overweight would require a WLI, or do I need to go and find an expert and ask them?

Given she wrote "eating disorder" a few lines above, surely it was obvious this was just a typo?