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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

To ask for experiences of mirtazapine?

51 replies

struggling26 · 10/01/2026 19:38

Hello. Long story very short: I am having a very tough time at the moment due to an experience last year which left me with PTSD. I’m awaiting trauma therapy and I’ve had a few short term prescriptions of diazepam from the GP in recent months to help manage acute distress and panic. I get really good short term relief from Diazepam, but it doesn’t seem to be agreeing with me anymore due to heavy sedation and a very unsettled feeling the next day. As a result my GP wants me to try mirtazapine instead as a more longer term solution (rather than using diazepam in the shorter term to manage acute crisis periods). I have IBS too and cannot tolerate SSRIs such as sertraline - GP said this is less likely to cause anything like that as a side effect.

anyway, does anyone have any anecdotes about mirtazapine? Either good or bad? Especially in terms of reducing anxiety/panic and improving sleep / mood etc, but also in terms of GI side effects? Is it a good alternative to diazepam? Thanks 🤞🏻

OP posts:
MarchionessVonSausage · 12/01/2026 23:52

I'm another person who had to stop using this due to extreme hunger and weight gain. I don't have a sweet tooth at all usually, but suddenly I was scoffing cakes & chocolate and never felt full no matter how much I ate.

I use escitalopram (Lexapro) now which has worked well for years.

Best of luck to you in finding something that works x

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