Is it the begining of the end for Weight loss injections?

[BeginingoftheendforWLI]

Just watched a report on BBC news, they did an item on a woman who had type 2 diabetes and was prescribed Mounjaro, doctors were impressed she managed to come off insulin within a month. She had some weightloss and now goes to the gym regularly.

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition - they simply don't have this data at present.

Feel like this is going to be big news in the foreseeable future.

Not sure that’s quite the gotcha you seem to think it is seeing how outdated they seem to be on women’s health, where it’s typical to diagnose even serious conditions as “fat” and/or “anxiety.

I’ve seen negative takes from GPs online and find them generally to be light on science and heavy on misogyny and fat-ist personal bias.

Two of DH's golf buddies are GPs and they're both on WLI. So, meh......

Of course he is….

And my GP has had to consult his Clinical Reference Guide book for pretty much anything I’ve ever gone in for over the last 20 years, so I really wouldn’t expect him to be knowledgable about Mounjaro.

They’re called GENERAL practitioners for a reason.

Sad, but so true. Still remember my GP saying admiringly that 'I was far better informed about HRT than they were' because 'It's not really covered in medical school.'

Considering he was near retirement it made me wonder if he'd bother to update any of his medical knowledge during the previous 30 years? Or just not bothered about HRT because, you know, it's only something to do with women.

Does he now? Best he doesn’t take them then.

He can have an opinion but he’s no more knowledgeable than anyone else not involved in the research, is he?

What are his thoughts on the positive effects for diabetics?

I’m praying for you and myself going through a very similar traumatic experience

having to also suffer the side effect of feeling good about how I look again

I don’t even want to comfort eat that’s how bad it is 😉

So many heartbreaking stories on here @HRTQueen. I've lit a candle for everyone who can now bear to look at themselves in photos. I hope we can get through it together.

FWIW, a friend has just told me that he's moved from 'diabetic' to 'pre-diabetic' thanks to Mounjaro. (He's not yet at his goal.)

The pain is real. I bought a pair of jeans in a size 10, got home and tried them on And. They're. Too. Big.

So now I have to trek back into town to exchange them and I hate going into town.

Damn you Mounjaro [shakes fist at the sky]

I absolutely loathe all the pissing about with returning clothes, that sounds genuinely irritating!

Maybe some concern troll will start a new thread about it, make a change from the ones about unnamed friends in various medical professions/research posts, and colleagues who are on WLIs and have KFC every day.

I've decided to reframe my arduous trip into town in a more positive light by skipping into the shop whilst loudly asking if they have the jeans In. A. Size. 8.

Oh yes depression can be sorted by pulling yourself together and getting out for a walk everyday!

When some people can’t even get out of bed! 🤦‍♀️

At 60, 5’6 and 17stone I was on :
blood pressure meds - FOR LIFE
statins - FOR LIFE
metformin - FOR LIFE
Thyroxine - FOR LIFE

I had lost and regained 3 to 5 stone over a decade since being on steroids for an autoimmune condition. (Which was eventually cured with surgery) however the steroids had made me insanely hungry and my portion control was non existent.

I had been on the ‘eat less move more’ diet. The Atkins Diet, Keto Diet, 8/16 Fasting diet. Cambridge diet. All were successful to a degree but all had the same thing in common. Completely unsustainable.

Read the study produced by Kings College Hospital in 2016. A study of 50k people with simple obesity (BMI 30+) and morbid obesity (BMI 35+) showed that women with simple obesity had a 1:124 chance of diet and exercise successfully getting them to a health BMI. For Morbid obesity it was 1:210. The saddest part was that even for those single minded ‘1s’ . 78% had put it all on again and more within 5 years.

This was my position. Because of years of yoyo dieting, I had made myself insulin resistant. Then came the miracle of Mountjaro. I went through the doses every month as prescribed. Once I lost the weight and was a healthy BMI of 22. I titrated down the doses until I arrived at 5mg weekly which is what I maintain on.

My GP could not prescribe as it wasn’t rolled out by the NHS when I started and when it was, my weight had decreased significantly so I couldn’t qualify - however she monitored my journey and reduced my medication to the point where I now take :
Thyroxine (half my previous dose) for life
Mounjaro 5mg.

This utterly baffling argument put forward by people that they ‘wouldn’t want to be on a drug for life’ tells me one thing. They are entirely ignorant of the health effects of obesity and just how much of the NHS resource Obesity sucks out of it. If you are clinically overweight or Obese the chances that you aren’t already on numerous drugs ‘for life’ already - is vanishingly small.

I have dramatically improved my own health and at my own expense cut the cost of the vast array of drugs supplied by the NHS to keep me in the status quo of obese but functioning.

Also your ‘for life’ would probably have been significantly shorter if you hadn’t lost the weight.

I too am baffled about all this faux concern. WLI are pretty safe (much safer for you than being morbidly obese). We in the medical profession class them as miracle drugs really. Yes, at the moment we don’t know the answer as to the benefit or negatives from long term use. But that’s about it really. No point worrying about 40 years down the line when some people would have been dead within 10 years without them.

It's not at all baffling if you bear in mind the concerns aren't really about obese people's health. They make perfect sense when considered in the context of worry from others about the relative loss of position in the hierarchy.

You make a good point!

It's only baffling if you assume, quite naturally, that these posters are genuinely caring, concerned people.

But they're not. In reality, they're actually just embittered and resentful that life changing weight loss is now achievable for millions of people. There's also their added envy that there are people who can easily afford WLIs and intend staying on them long term. It's not fair!

Stay on these threads long enough and invariably these bitter people reveal their true colours. Their faux concerns degenerate into spiteful sneering and insults.

We. See. You.

And this, of course, is why the best option is to poke stupid with a stick. Make them seethe.

Hardly criticism in this thread. Most comments I’ve seen here are positively evangelical about WLI. There will be side effects no doubt but there are also side effects from crazy diets and remaining significantly overweight so you takes your chances.

Well yes. They've transformed my life. I'm so very grateful for them and the fact they've made a reality something that was beyond my ability without them. In the same way I'm grateful for hrt, antibiotics and vaccines and will defend my use of them whilst respecting other's choices not to.

Oh good they’re talking about it now on good morning Britain. Woman pointing out how useless women’s health research is.

Carolyn Harris labour MP wants the BMI lowered. People hampered by weight waiting for operations should get it. She’s on a maintenance dose and pays privately.

She’s being asked about people getting round the rules. And if she’s just doing it as a “lifestyle choice”. She’s pointed out she’s done every diet, never lost this much weight, and it’s basically a miracle. And will save NHS billions.

All my friends who are doctors have said the same, they have said so many issues would be resolved if people were closer to a healthy BMI that they could actually see the patients they need to or treat their current ones better.

A friend of mine is pretty overweight and has sleep apnea amongst other things, she isnt high enough to qualify for NHS but all her weight is round her tummy/chest so it would help her massively to lose weight. She cannot afford it privately.

Makes a lot of sense.