To have turned down Munjaro?

[Uberella]

In 2020 I was diagnosed with type two diabetes;I have since then lost 6st in weight to try to help;I was huge at 5ft 4in and a whooping 22st 10lbs.

Roll on now;unfortunately despite my weight loss I’m really struggling with my diabetes at the moment;My blood sugars are really high even when I’m not touched anything sugary.

I’m currently on insulin and statins for high cholesterol.I’ve been told multiple times in the last few months I’m at risk of early death.

which is why I’m wondering if I was right today to have turned down munjaro jabs when offered them during a routine treatment review today.

I know I need to lose more weight;I’ve been doing slimming on and off for a few years but I’m terrified of the munjaro jabs;I know people who have suffered terrible side effects from these jabs plus weight gain after stopping the jabs and I’m not liking the things I’m hearing in the media about it.

I saw another pharmacist at my GP surgery a few months ago that I don’t normally see and he said to me that he doesn’t personally recommend Munjaro as there is evidence it causes hepatitis.

‘Shame on you’ - really? I don’t need to be shamed for suggesting that the pharmacist was batshit. He absolutely was. Of all the potential side effects and complications of Mounjaro hepatitis isn’t up there. It’s a miniscule risk in comparison with all the others and when you balance it over the health benefits it really does become even smaller.

If the pharmacist had listed possible complications and hepatitis was one of them, fair enough. But to suggest you should not take it due to a risk of hepatitis definitely was batshit. So shame the idiotic man who told you that, not the people who are sensible enough to consider all aspects of the drug.

I’d go in MJ in a nanosecond but I have type 1 diabetes and it’s not approved for that. I think the benefits far outweigh the risks.

I’d rather take mounjaro than insulin and statins.

i recommend you read some of the many threads on here about it. That way you will hear real stories from real people rather than the clickbait dramas in the daily Mail and the like.

personally I’ve lost 4.5 stone over 8 months at roughly 1-2 lbs per week. I really don’t have any bad symptoms other than being a bit burpy for a fee days each week.

putting weight back on after any diet is a risk - you can put it back on after weight watchers and slimming world but that hasn’t stopped you so why the fear with mounjaro?

as for causing hepatitis - that’s just bollocks

OP - I have diabetes (on insulin) and am overweight. I don’t eat much and for a while refused ozempic because I didn’t need appetite suppression (my dr said that my insulin resistance was my main problem which was making it hard to control my blood sugar and lose weight).

My dr convinced me to try Mounjaro as it targets insulin resistance, inflammation- not just appetite suppression. At first I wasn’t sure as 2.5ml and 5ml doses made no difference to my blood sugar. However moving up to 7.5ml and 10ml has been a game changer, my hba1c has gone down and I’ve lost 10kg.

I think it’s worth a try

Good on you for researching - but make sure you don’t just do opinion papers but actually read the published peer reviewed studies. You can find most of them on PubMed.
and while you are at it I urge you to properly research the consequences of your uncontrolled diabetes… there is a tiny tiny risk with MJ (as any meds) but an almost certainty that your diabetes will cause you awful effects. I’ve seen it - it’s not nice at all.

Oh I’ve been on it since October. Lost 5 stone, feel fab and barring the odd bit of nausea no ill effects.

I keep on creeping near the pre diabetic range and I have just started monjaro. But I'm doing fasting and have been on and off for around two years. During the week I don't eat anything from 9pm until 1pm the next day. I test my blood sugars at home and this has kept my sugars vert stable.

Weirdly the less I eat, the less I feel hungry. My brain was telling me I felt sick, I felt dizzy. But I'm not not. After a few weeks I honestly don't even feel hungry by 1pm.

I eat as I feel at the weekend.

Have you got a blood sugar app? I find the that was very insightful and I do my finger tricks in my thigh as it hurts less and gave the same readings as my fingers.

Bluntly, yes thats daft.

Im on Ozempic, but they all do basically the same thing, these jabs will reduce the amount of insulin you need to take because they improve how you respond/reduce how much you need.

I've cut the amount of fast acting insulin I take by two thirds! Some days, more than.

That has had a significant effect, meaning I can eat more fruit/veg and have a healthier diet.

Talk to your Diabetes nurse again. Ignore what silly people say, these drugs were designed first and foremost for diabetes control/management!

Many pharmacist have not studied up on Mounjaro and Zepbound as they are fairly new medications. Our small town pharmacist, who's been a pharmacist for 30 years, didn't understand the drug fully when I chatted to him about it, but he's learning.

I get my Zepbound from LillyDirect self-pay for $500/month, through a Telehealth clinic.

I found this article from Which you might find useful

https://www.which.co.uk/reviews/nutrition-and-supplements/article/weight-loss-injections-wegovy-vs-mounjaro-private-costs-and-nhs-options-explained-aCic43r0uxdE?utm_campaign=home&utm_medium=social&utm_source=facebook&fbclid=IwZXh0bgNhZW0BMABhZGlkAAAGNeLVmJwBHggjXuNKPG69YmqoeZymwuO4RbVSALpCp6J212f7FNRalBuQSMzbTOMU2Fyx_aem_KGHy8on_pEq6vQvoqD6_Kw&utm_id=6828457379996&utm_content=6828506127196&utm_term=6828457380396

Sure, whatever, you knew what I meant, clearly (And I’ll post how I like, I think I’ll quote the OP more, knowing how much it bothers you….)

Yes some (not all) are taking it inappropriately, which muddies the waters.
If a person is concerned about the real (as opposed to fake stuff on social media), known, and serious side effects of a new drug, I would never try to persuade them to take that drug. They’re telling you that if they got those serious side effects, it would not have been worth it for them.
It’s an amazing drug, but it’s one treatment amongst many and it’s not for everyone.

I was taking MJ for a few months but despite being morbidly obese have stopped taking it. I am not diabetic. My main concern is that I feel like my eyesight has deteriorated and obviously that's not something I want to risk further. Also has awful diarrhea and nausea.

The reason people are ridiculing him/her is because the information they gave you is completely inaccurate and illustrates the fact that they know nothing about it and they're not in a position to recommend or otherwise as their information is wrong.

Mounjaro can causevpancreatitis (which has nothing to do with your liver apart from it being in the same area of the body) in mice. It is contraindicated in people with gall bladder problems, again nothing to do with the liver apart from it's general location.

That is the reason people are shaking their heads at the pharmacist, who unfortunately needs to do some reading before running their mouth with incorrect information.

I don’t have any side affects, just weight loss and all the health benefits shots that go with it. Listen to Dr Tyne’s podcast. Most of the scaremongering isn’t factual. All rapid weight loss can potentially cause these same health issues. The key is slow steady loss and Mounjaro can really help you achieve that while also helping with your blood sugar issues. My dad suffered seriously with his diabetes and the suffering I saw before he died of diabetes related health issues was horrendous. I’d rather have Mounjaro’s worst side affects than that.

Speak to health professionals who know about glps and don’t have a vested interest in keeping you fat and sick (like big sugar who are putting many of the scare stories out there!)

Out of interest, are you seeing people with panic attacks and racing heart? That was my experience - day after the jab woke in the early hours, heart rate 140, absolute rolling panic up and down my spine. Continued for 3 days and even if you paid me £1000 I wouldn't take it again. Threw the pen away!

And it was from Voy so definitely not a dodgy back Street dealer.

I do think you are being unreasonable not to try it, seeing as you are still overweight (despite a previous fantastic loss which you should obvs be very proud of achieving) and still struggling to get your diabetes under control.

I lost 4.5 stone with Mounjaro (from BMI 30 to BMI 20) and it’s like losing 15 years of aging. Back at the gym 6 days a week, cycling for transport and dancing for fun. This time last year just climbing the stairs made my knees hurts.

Side effects have been extremely minimal for me, but if they had been difficult (as they are for some people) I would’ve just stopped or switched to one of the other injection types to see if they were more tolerable.

I really cannot express how sincerely I feel that Mounjaro has given me my life back.

OP I tend to be quite conservative about medicating, and especially newer drugs and uses. But in your case it seems to me that your risks from your weight are much greater than from taking the drug.

I would be worried about gaining later and I think you will need a good plan to deal with that.

I was at a cosmetic clinic the other day, getting some fillers for marionette lines which have become a problem since my weight loss on MJ. The person doing the procedures was a doctor. She had never heard of MJ, when I mentioned I has lost weight on it she said "what's that?". I have to say I lost some confidence in her.

There is no evidence of this, so far as I'm aware, unless people are sharing needles?

I do think there are a lot of scare stories in the Press about MJ side effects. It put me off for quite a while but then once I started to do my own reading, I was pretty surprised. I’ve been on MJ for nearly 6 weeks and have lost 11lbs. I’ve had some minor side effects such as heart burn and constipation but it’s all been very treatable with over the counter stuff.

It’s been the easiest thing I’ve ever done. I’ve overhauled my diet and now find myself actually craving vegetables (unheard of for me!) and even when I’m hungry, I still find it really easy to choose good foods rather than fall face first into a takeaway. I can cook for others and not feel the need to eat it. I can go to a BBQ and be really content with having one burger and not need to hoover up potato salad, crisps, dessert and wine. For many, it’s a life-changing drug which buys them time to ‘reset’ their relationship with food. Of course I’m already thinking about what it looks like when I get to my goal weight but I’ve still got 5 stone to lose so I’m just focusing now on developing a taste for good, wholesome food and not some of the rubbish I used to eat.

I pay for it (as I imagine many do) but it’s worth every penny.

In your situation and especially with the warnings about your health, have a good read and give it some serious consideration. It’s obviously your decision but for me, I’m so, so glad I did it.

I’d go for it. I’ve had zero side effects. lost 2 and half stone and it’s been life changing. I no longer hate my reflection. My clothes fit again
I don’t cry to myself. I can walk, bend, move everything is better.

Mounjaro was successfully used to treat diabetes long before the weightloss benefits came to light. In your shoes especially knowing you would like to loose more weight I would jump at it. I am paying privately for it as a treatment for obesity and have lost 3 stone since October and I am half way to my goal. It is life changing or me. I have lost weight slowly compared to some which I hope will help me keep it off. I don’t think you are more likely to put it back after mounjaro than any other diet. The side effects have been very manageable for me. A bit if nausea, bloating, indigestion. Pepto bismol or peptac settles it. The two worst times were after eating chinese takeaway and dominoes so I think a lot of people who suffer do so because of what they eat, although some are just unlucky. Do your research. Don’t dismiss it out of hand. All meds have risks but so does being obese or struggling to control your blood sugar.

Are you sure it was hepatitis and not pancreatitis? Mounjaro/Ozempic do increase the risk of pancreatitis, and there is evidence of elevated risk for several other conditions (including macular degeneration). All drugs have risks, it’s a matter of balancing the risks against the benefits. If people are a relatively healthy weight, the risks should give them pause if they’re thinking of taking the drugs as an easy way to drop some weight (which a close friend told me they were thinking of doing). But the risks of the drugs are very small compared with the risks of obesity and uncontrolled diabetes.

I’d check her medical credentials. 😂