To have turned down Munjaro?

[Uberella]

In 2020 I was diagnosed with type two diabetes;I have since then lost 6st in weight to try to help;I was huge at 5ft 4in and a whooping 22st 10lbs.

Roll on now;unfortunately despite my weight loss I’m really struggling with my diabetes at the moment;My blood sugars are really high even when I’m not touched anything sugary.

I’m currently on insulin and statins for high cholesterol.I’ve been told multiple times in the last few months I’m at risk of early death.

which is why I’m wondering if I was right today to have turned down munjaro jabs when offered them during a routine treatment review today.

I know I need to lose more weight;I’ve been doing slimming on and off for a few years but I’m terrified of the munjaro jabs;I know people who have suffered terrible side effects from these jabs plus weight gain after stopping the jabs and I’m not liking the things I’m hearing in the media about it.

I saw another pharmacist at my GP surgery a few months ago that I don’t normally see and he said to me that he doesn’t personally recommend Munjaro as there is evidence it causes hepatitis.

That’s the most bizarre nonsense I’ve read to date!

I take Mounjaro and side effects have been minimal. I have lost 2 st 11 lb since the end of October, so not fast which I am hoping that will make it easier to keep off. The risks I am at from obesity outweigh the risks of the jab for me and it has been life changing. If I had diabetes and could get it free on the NHS I would jump at it. I pay privately. Do some research for yourself and then see how you feel. I have never heard hepatitis being associated and I have read a lot about It.

My relative is on monjaro for diabetes.
since being on it her levels have consistently been going down- yes there has been weight loss but that’s an added bonus.
Diabetes is quite serious- you’re lucky to have been offered it on the nhs.
You could always give it a try

Definitely try this diet. I have been doing it as I am pre diabetic and am losing weight for the first time. Good luck with whatever you decide x

I think you are mad tbh. It’s a life changing medication for people in your situation. You don’t even know if you would have suffered any side effects but even if you did you have to weigh up the pros and cons. You could have at least tried it and if you did suffer badly not continued. You were offered a piece of good dust today. The vast majority are paying £150 ish a month for theirs.

Surely your GP outlined all the pros and cons of side effects of weight loss injections versus health damage of being morbidly obese with uncontrolled diabetes??

and yet you choose to listen to heresay and scare articles?
Any pharmacist giving out false information about hepatitis should be struck off.

If you raised this as a concern with your GP, they would have quickly corrected this misinformation .

you do know that you are at extremely high risk of liver damage from being morbidly obese?

You obviously worked very hard to loose 6 st and want to lose weight. Don’t let all that hard work be in vain. Accept the extra help via weight loss injections recommended to you by your gp.

The hepatitis thing is utterly batshit

I think it is worth doing especially if you will be monitored by a gp. You just need to follow advice - hydrate, eat regularly and keep your doctor in the loop about any side effects.

I would at least try it in your position.

Have a read of this. Mounjaro not just helping weight loss but also blood sugar and blood pressure.

BBC News - Mounjaro vs Wegovy: Weight-loss drugs in head-to-head trial - BBC News
https://www.bbc.co.uk/news/articles/cy75dk8kjr1o

The only way Mounjaro will give you hepatitis is if you share a needle with someone who has hepatitis. Don't do that and you'll be fine 🙄

If the fear of some short term side effects is greater than the fear of dying from diabetes then turn down Mounjaro by all means. Millions of people are on Mounjaro with no ill effects, losing weight with very little effort.

Your GP is wrong.

You quoted the whole OP, @BoredZelda, just to make a comment that shows you didn't read/comprehend it.

Its up to you, but it seems to be one of those medications that they're finding more and more benefits for

Is it ok to take Mounjaro as well as being on HRT?

You're focussing on Mounjaro as a weight loss medication, but for you it would be prescribed to try to control your diabetes and any weight loss is a positive additional outcome. Why would you turn down a medication that has been shown to be extremely effective at treating your condition? Your GP would likely keep you on the lowest dose that controlled the diabetes, rather than increase it just for the weight loss.

I know it's because you're scared of taking it, but those fears are not in proportion to the actual risk of side effects. You're basing a medical decision on stories from friends and from the media, that's not a reliable and reasonable source of information.

I'm taking Zepbound, which is the same as Mounjaro. I'm paying $500 a month for it and it's worth every penny. No side effects at all, just reduced appetite and weight loss. I can't believe you'd turn down this medication, especially when you're offered it for free!

People on Reddit are calling it a miracle drug as they've found it has helped them not only lose a lot of weight but has fixed many health problems they had, including fatty liver and migraines.

I have also have seen improvements to my health, which started in the first two weeks of taking it.

You’re ignoring the doctor over someone who told you mounjaro can cause hepatitis? Can’t have been a pharmacist, more likely just a boots employee

Why is mounjaro causing hepatitis batshit or hilarious?

Medications can cause hepatitis. There is at least one incident in the literature of mounjaro causing hepatitis. Generally though it's considered safe and the benefits to your liver (reduced NAFLD and better diabetes control) outweigh any risks.

Yes - YABU.

The drug was created for the treatment of diabetes and has been used safely for years.

Congratulations on losing 6 stones! That is amazing.

But you know you need to lose almost as much again, and it will be even harder than the first six. I also have uncontrolled diabetes, lost some weight (about 3 stones) several years ago, but I know I don’t have it in me to do the same again. So when I was offered MJ, I said yes.

They are monitoring me carefully because I have some liver issues, but the side effects I’ve had were very minor indeed. And even in the first few weeks, my appetite has changed, I feel healthier, sleep better and have more energy. I would honestly recommend you have another conversation with your doctor about it.

After any weight loss there is the risk of regaining it. That is true whether you use MJ or not. But if you don’t lose the weight in the first place, you’ll never manage to keep it off.

Yep

Hepatitis is just inflammation of the liver it's not necessarily caused by an infection. Inflammation can be triggered by medicines, alcohol, poisons etc so not a completely ridiculous suggestion - although I have no idea whether this is a reported side effect or not 🤷

It was never mentioned as an issue for me, prescribed on the NHS.

Hepatitis isn't a reported side effect, it's been reported rarely (once?) and without definitive evidence it was actually the Mounjaro causing it. It is bizarre for a pharmacist to warn people off using an appropriate medication for T2 diabetes by mentioning this. They should have discussed the actual list of possible side effects rather than scare monger about hepatitis.

Hepatitis is liver inflammation

Can be viral. Can be alcohol related. Can be medication related

There is a possibility you could 'get hepatitis' from mounjaro, there is a report in the literature, but it seems very rare. Poorly controlled diabetes will put more strain on the liver, but still it's not an eyeroll situation

I’d recommend speaking to someone who knows what they’re talking about. I’ve taken it for 2 years, no issues after the first few months, 6.5 st lost am on a maintenance programme; my 17yo has been on it for 9m, lost 4.5st, no issues just has another stone to lose; a friend with diabetes also on it. All of us under the care of endocrinologists. Blood tests (sugars, thyroid, cholesterol, liver function etc) all optimal.

I think, given you have diabetes and GLP1 meds have been tested with diabetics for several decades now, that you should speak to an endocrinologist before deciding whether mounjaro or a completely different medication would help you. Not a practice nurse, or even a GP with no recent training in diabetes and current medications. A diabetes specialist.