no beachcomber, i wont read the critique of a piece of research which comes from a third party, i prefer to read the research myself not someone else's interpretation. I read the danish study. None of the accusations that the putting children first website highlighted was particularly obvious to me. The conclusion i came to was that it did not show the link between MMR and autism. It did not examine certain things which would have been nice to look at, sure, and there were flaws, but IMO the whole paper cannot be abandoned as a result. No one paper can look at everything, but there has been a huge amount of work done now without proving a link. I look forward to a meta-analysis: but maybe you dont trust the cochrane collaberation either!
There are many other papers which have not shown a link. Dr wakefield admitted that the link had not been proven. I am not saying he has never done anything of worth, but that he, IMO, showed naivety and a serious lack of judgement with the lancet piece for the reasons i mentioned previously.
You accuse me of refusing to consider research on the basis of bias. That is simply not true. I will read the research, as i said before, and consider any conflict of interest in my interpretation of the results. Thankfully authors are duty bound to reveal any conflicts of interest (except Dr Wakefield didnt) which should inspire the reader to analyse whether the interpretation of results could be subject to that bias. I did not rubbish the lancet piece on the basis of Dr Wakefield's bias, i rubbished it because it mentioned MMR throughout the study when there was no reason to highlight MMR above any other possible environmental trigger or factor.
We all have to decide as parents who we trust and what to believe in. I have had to evaluate literature for the last 20 years with reference to my clinical practice. If you have ever been to a medical conference you will see that there are many different opinions, often contradictory, with every academic/ clinician trying to stick to their pet theory like glue. You are right, there is always bias. But it is the researcher's duty to remove it from his methodology and interpretation of results.
I am flabbergasted that you say the dr wakefield's science stands unchallenged! He is a prolific author is it true, but it was this paper that caused worldwide panic and the specific stating of MMR throughout the paper although there was no clinical or academic excuse for it. That is why i am focussing on it, however excellent his other work. Perhaps he was swayed by a few desparate parents and wanted to find something for them, i don't know.
You, however, have rubbished great tranches of research not because of the methodology, but because one or more of the authors may have, for example, advised a pharmaceutical company in the past. If the possible bias is stated, it does not completely rubbish the research, but you do have to look critically at the methodology.
I approach all of this with absolutely no axe to grind. I am genuinely impartial and objective. I find some of the posting quite offensive and of real concern: that some people genuinely think that there is a conspiracy within the medical profession and the pharmaceutical industry to hide any link i find quite shocking. The medical profession is constantly researching effects of licenced drugs, for example, and they are soon pulled if there is found to be any problems. rememeber all the issues recently with cox II inhibitors?
I really hope that people realise that most researchers are dedicated individuals and that there are rigorous safeguards when work is published and drugs are licenced. TBH it would probably be more profitable for the pharmaceutical industry if the WAS a link- it would be a huge race to licence an alternative vaccine- remember, they only have 7 years exclusivity in which time they would make a serious amount of cash before any company is allowed to manufacture.