It will be very interesting to see what happens this week, if Trump is unexpectedly running out of steam. This could come to a close sooner than many people expected.
I think the Republican party, having sealed the Senate and got the court they want, will be very happy to see the back of the Trumps. Very happy indeed. Active support for him seems to be non-existent. Moscow Mitch is already talking about next steps 'now that the election is over.' I think that is big.
I cannot see Jared, Donny Jr or Eric getting anywhere at all with a nomination. Pence has much, much more of a chance if they are looking to harness some of the (gag) energy from the Trump term. IMO.
Ivanka will need to prove her mettle against Nikki Haley. She'll fail.
I'm actually not worried about the heirs and spares being much of a nuisance in an active political role. On the telly they can do as much damage, earning more money, and without any of the bother of real work to worry about. They'll pick that.