@Shockingstocking. Sorry, I think you were talking about the literal fact that having a vaccine wouldn't kill people, and I took it slightly differently. I DO think that the focus on a vaccine and the willingness to keep many areas of the NHS closed until it arrives will kill people. The original three-week lockdown was very obviously the right thing to do, no question. But, like very many of us, I am uneasy about keeping major parts of the health service closed for 6 months +.
Was reading one of the summaries on Nature.com yesterday and this troubled me. If children don't get infected at their usual rate with one of the other coronaviruses, will they start to be more at risk from covid-19 than they have been so far? At the moment, every sign of a temperature or cough in a school age child is a disaster, and leads to them quickly being withdrawn. But maybe we should be aiming for 229e parties?
'Most children infected with the new coronavirus show few signs of illness, if any. But a few children are struck by a severe form of COVID-19 that can cause multiple organ failure and even death. Now, scientists have begun to tease out the biology of this rare and devastating condition, called multisystem inflammatory syndrome in children, or MIS-C.
Doctors have diagnosed hundreds of cases of MIS-C, which shares some similarities with the childhood illness Kawasaki’s disease. To understand MIS-C’s biological profile, Petter Brodin at the Karolinska Institute in Stockholm and his colleagues looked at 13 children with MIS-C, 28 children with Kawasaki’s disease and 41with mild COVID-19 (C. R. Consiglio et al. Cell doi.org/d8fh; 2020). The researchers found that compared with children with Kawasaki’s disease, those with MIS-C have lower levels of an immune chemical called IL-17A, which has been implicated in inflammation and autoimmune disorders.
Unlike all the other children studied, children with MIS-C had no antibodies to two coronaviruses that cause the common cold. This deficit might be implicated in the origins of their condition, the authors say.'