MN seems to have every woman on here, or their relatives, who have conceived and had a live birth, over 40.
Statistically the odds are against you and for most, it won't happen.
I had a late miscarriage at 40. When tests were done, I was told it would be very doubtful that I'd have a live birth. I'd previously been very fertile.
You have a 5% chance over 40, of getting pregnant, without any help. Many of us aren't told by the women we know over 40, what help they had. Coupled with a, higher miscarriage and still birth rate, many women struggle with infertility over 40.
It isn't a case of IVF or nothing, though.
OP, I'd advise your friend to have a chat with her Doctor. She should get herself as healthy as possible, eat as little processed food as she can, take supplements and exercise. It does help to get your body running as well as it can. Then if the doctor can help, she will respond better to any side effects.