I'll paste something I wrote in a parallel thread, if it helps kick it off.
"TBF, drugs companies tend to hide bad results. It's a well known practice, which is not to mean that everything that comes out of drugs companies is bad or useless.
Taking it with a pinch of salt, as with most things, I'm more willing to accept that some new drugs are close to useless than dangerous.
Same with vaccines."
Adding that it's very difficult to publish negative results in peer review papers anyway. It's a situation that every scientist is aware of and we all agree that it shouldn't be the case, but it's still hard because scientific journals want to sell and be cited.
I've struggled with a similar issue during some of my research, as the people who had made attempts at something hadn't published their results and we only became aware through personal communication but without methods.
This to say that lack of reporting is both an endemic problem within science and an ethical problem with medical trials, at different levels, as there's a lot of time and money involved in general.
Having said that, and from what I know, it's not as bad as anti-vaxxers claim.
Certainly a lot better than in the beauty product industry.