There's a big difference between Mickey Mouse degrees and good vocational degrees. A good technical degree for example brewing technology will give you hands on experience of technical processes and prepare you for the industry- you'll probably get an industrial placement too. Such a degree is worth having.
Degrees where you're not getting technical expertise are the ones to be wary of. However interesting the subject is, if you can study it as a hobby in your spare time, don't bother. I'm talking about things like art history, women's studies etc. All interesting and worthy but highly unlikely to get you a job I'd count things you might not expect like psychology and law as a first degree in that category too. If you want to do law get another degree first, for example biotechnology and then go into patent law.
The ranking of the whole university doesn't always reflect the quality of the course. Medicine at Oxford for example, wasn't highly thought of when I was at uni.
Did you select your Uni choices based on rank?
Sort of, yes. There were several I considered, all red brick, but the course I chose was the best of its type in the country. Having taught at a couple of units I can honestly say there IS a difference in the calibre of student, course and staff.
Would you rule out a potential employee based on their University ranking?
Sort of, yes. I'd go for one with a degree in biochemistry from Nottingham over an ex poly, for example.
Has your degree helped, regardless of where it was from or has it worked against you?
It was essential but not sufficient. I needed a PhD and several years of experience to get where I am.
My advice to you, as an ex academic moved to industry, is that experience is vital. If you're offered an internship, placement etc, grasp it in your grubby little paws and take it and network, network, network. Use your academic contacts to start talking to people and attending events. Qualifications alone don't get you in the door.
Best of luck!