Here is the international expert panel summary on baby E
Baby 5 (Child E) was a 29+5/7 week, 1327 grams birth weight, twin 1, male infant, who was born by semi- elective
Caesarean section for twin-twin transfusion syndrome, with oligohydramnios. Antenatal ultrasound showed dilated small
bowel loops and absent/reversed end diastolic flow. Baby 5 required bagging at birth and continuous positive airway
(CPAP) for apnoea. He showed signs of infection with low white cell and neutrophil counts, and high blood sugar, which
were treated with antibiotics and insulin. Chest x’ray was clear. Four days later, he developed respiratory distress
(desaturation, chest recession, oxygen need) and bilious aspirates from the nasogastric tube, but the abdomen was soft
and not distended. He had two episodes of massive gastrointestinal bleeding with at least 25% of estimated total blood
volume aspirated from the nasogastric tube. He was given normal saline but 40 minutes later, he suddenly deteriorated,
with desaturation, poor perfusion, low heart rate 80- 90/min, and purple patches of discoloration over the abdomen. An
hour later, he collapsed again and died despite resuscitation efforts.
CONVICTION
It was alleged that Baby 5 died from inflicted trauma causing upper GI hemorrhage, and intravenous injection of air,
causing air embolism resulting in collapse, patchy discolorations of the skin and death.
PANEL OPINION
Baby 5 was at high risk because he was preterm, had twin-twin transfusion with oligohydramnios, and his antenatal
ultrasound showed reversed end diastolic flow and dilated small bowel loops. This meant blood was being sucked out of
the fetus at the end of each cardiac cycle, and the intestines were likely damaged before birth. The 2 episodes of massive
gastrointestinal haemorrhage were most likely due to in-utero hypoxia causing stomach or small intestinal ulceration,
and erosion into an intestinal blood vessel; or to a vascular abnormality like Dieulafoy’s lesion, which can cause life-
threatening hemorrhage. His 25% blood volume loss was likely an underestimate because more was likely lost in the
intestines. Emergency transfusion with group O negative blood should have been immediately given earlier during
resuscitation. Since 20% blood loss causes shock, and Baby 5 lost much more, this was fatal. Patchy skin discolorations
are caused by dilation and contraction of small blood vessels in the skin in response to hypoxia, which can occur in many
conditions and are not diagnostic of air embolism. .... If air was deliberately infused through a central venous line to cause air embolism, the line will have to be
reinfused with fluid to prevent detection. Collapse from air embolism occurs instantaneously. It is doubtful that this can
be achieved quickly enough before other staff in the unit respond to the collapse.
CONCLUSIONS
- Baby 5 died from massive gastrointestinal hemorrhage due to either intrauterine hypoxia causing stomach or intestinal ulceration or a congenital vascular lesion.
- Emergency blood transfusion should have been given much earlier.
- There was no evidence of air embolism
- Post-mortem should have been requested
[One of the consultants who later accused Letby told the parents no post-mortem was needed]
[Link to combined summary document from https://ripe-tomato.org/2025/06/05/lucy-letby-baby-codes-neonatal-unit-classification/ , section 2]