I take medication that constipates me. I take 2-3 sachets a day, but if I don't go for 2 days I am supposed to up it by one sachet each day. So I took 5 sachets yesterday, and today will be six sachets. However, I'm worried about it working in the middle of the night (I don't always wake up when this happens because of my medication side effects). What time of day is it best to take the sachets today (and tomorrow if I don't go) to avoid them working in the middle of the night?