Mums of teenage boys with cystic acne - when did you start noticing a difference with Lymecycline? My 16 years old son had an awful acne breakout in the last couple of months and he's been using epiduo which has seemed to make it worse rather than better. The gp has prescribed him Lymecycline and he's been on it for 2 weeks now. I could really do with success stories right now. Thanks