Nothing directly life-changingly awful but just a grind of continuously crushed hope.
The things I do and the way my social networks are spread were heavily impacted by restrictions. All my external purpose was either taken away/ switched on/ off at short notice for 18m
I loathed the 15m of living in DH's office when one of our rooms was commandeered for the great WFM effort, and the constant relentless noise of his calls/ voice carrying through the house due to the acoustics. Fortunately he was no great fan either and quietly snuck back to the office long before his hyper cautious HQ authorised it. I was constantly hushing children to not disturb Very Important Work.
Because of all the hysteria over following the rules in 2020 plus many people adding extra caution, my children went 6 months without playing with anyone other than their sibling. DS1 who was newly diagnosed with ASD coped OK but DS2's friends were allowed to school and grew up without him while he sank into a depression. He was y2 in 2020, and it's only really now in y5 that he's really re-finding his social confidence and getting his learning levels back on track. Home learning was a daily torment. In winter 2021, DS2 would sob daily into my lap through the live lessons, tormented by seeing half the class on screen. Still he was not allowed into school despite the obvious toll on his learning and wellbeing.
My family are spread and my family connections have fizzled. Some family members hunkered down and lost interest. Some friends and younger family have been swept up with keeping up with the pace of life and had no spare capacity left. We didn't have a "bubble" and being a family of 4 took us over "The Rule of 6" which people we knew took seriously in 2020.
It's 3 years since we saw MIL. She died this summer. She was old and frail but the travel and health/ care restrictions meant that she couldn't see the DCs in person until her health was too fragile to make travel plans. We went over in 2021 but only one visitor was allowed. At least DH saw her several times in her last painful, joyless year. She was never going to be immortal or re-find good health and lengthy restrictions (worse than the UK) took away the last of her independence and stiffled her family life. It was like the restrictions had a flawed purpose of preserving her as a museum piece, but not allowed to really live.
I've had a shock, young family member bereavement. I'm not sure of the role of restrictions in triggering it. It is a plausible possibility.
I used a lot of internal fight to get through 2020, and the following winter finished it off. I'm pretty sure I was depressed through much of 2021, but the increased routine from the September pulled it back. I still haven't got my sparkle back though. Life is still throwing up disruptive curveballs (not necessarily Covid related) and I still can't feel excitement and anticipation because too many nice things have been cancelled, disrupted or had all the fun restricted out of them. I enjoy good moments and am normally back to feeling a normal emotional range, but I still do not trust that something nice will happen until I am actually doing it, and I miss it. I suspect the cure will be consistency.
The wider social damage we're seeing was inevitable, and it's horrible seeing that it's come to fruition. I spoke up about it early on and was constantly shouted down for being a Granny Killer because I cared about more than just Covid. I hope that the inhumane restrictions of 2020/21 are never repeated; the toll on the population has been at least as bad as the illness was itself.