Humira seems pretty good if the company has any to deliver.
Going through MTX asap and finding out whether it works or not seems to make sense if hoping to start TTC, as Humira is OK for that, but most places insist that MTX has been tried at least before funding is approved - if you tell them at an appointment that you want to conceive, they'll be able to advise you with that in mind. And on a purely mercenary note, as Humira is used for some people TTC off licence, it certainly won't hurt to have the medicine already approved and funded/treating your inflammatory disease, rather than trying to stretch to pay for that on top of all the other IVF treatments and procedures.
I definitely don't have as many side effects from it compared to MTX, anyway, which was sort-of-working, just not enough. I can get a headache immediately following it and get tired the next day, but I have it at night and sleep through the headache/have an early night after work the next day.
For example, my injection was 9pm Thursday, I slept fine, felt a bit rough at 5.45am when I got up Friday and work was a bit of a slog (it being the first day of my period hasn't helped). I went to bed at 10pm last night, woke up just after 7 today and I feel, well, OK - I spent a long time in the bath this morning and could feel all the little facet joints gradually loosen and free off in the process of gently stretching in there. I'm pretty sure that my feet are less swollen because a lot of my shoes seem looser, too.
However, where hip pain is concerned, I'd say get your Vitamin D levels checked. Mine was ridiculously low and my hip had been horrendous for years, despite a memory foam topper, supportive shoes (and a fucking walking stick for three months). Since I got up to better levels, it took about six months, but the pain in my hip completely vanished before starting Humira. I just had pain everywhere else to deal with
Other people, though - they're the real problem. Especially the 'Well, everybody gets backache' types. I'm politely bullish now, and not above mentioning to HR that I'm sure they didn't mean it that way, but comments about laziness regarding people who are unable to lift or stand for prolonged periods would be problematic in terms of Equalities Legislation/potentially be seen by a union, ACAS or a Tribunal as Discrimination towards people who have a Protected Characteristic.
Guess who doesn't encounter issues when it's 'normal' for staff to stand up for four hours, but smiles and fetches a chair or says 'of course the boxes will be moved, I'll call Site Team now, as they've got the equipment to do so safely'? Believe me, it took a long time getting to this point, but I don't have to apologise for having a disability and other people don't have a right to criticise - and even if they do, they can Fuck Right Off.
Reducing inflammation has another benefit - it really helps your mood, as it's not just pain, lack of sleep and the inherent physical restrictions that affect it - inflammation in itself is now being seen as a cause of low mood. I found this out initially when having steroid pulses, where feeling tearful lifted within a couple of hours and the next day always felt 'happy' - now I feel far more on an even keel - and research is backing this up.