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Can I ask about your experiences with antidepressants?

85 replies

Coffeeisnotmycupoftea · 05/05/2026 10:06

I didn't want to put this on the Mental Health board as I assume most people on there are in my position and needing help, I wanted to ask this as an all round question to not only people in full mental health crisis right now but also those who may have found themselves on the other side and feeling well again.

I think that I need to try anti-depressants but every time I try I am wracked with fear to the point that I just can't do it. I know I need to grow up but I am genuinely paralyzed with fear.

As I type this I appreciate that it must seem ridiculous to many people and I am fully aware that it is more than likely my poor mental health talking me out of it all but I just can't do it.

It's not about the stigma of mental health medication, I honestly couldn't give a toss about that, nor is it the fear of being 'hooked' on these meds because tbh, if they were to change my life for the better I would be more than content to be on them for life.

It's how I feel now and the fear of being made to feel worse by the drugs. Anti-depressants appear to have such a reputation for awful side effects and sufferers having to push through feeling much worse before they feel better and this could be weeks to months. I just don't think I could cope feeling any worse than I already do. I have daily gut issues which completely control my life (and yes, I have tried everything else, literally everything to ease these issues), my anxious state of mind is high 24/7, I have visceral hypersensitivity so feel everything stronger than I probably should do (every ache, pain, weird sensation in my body), my health anxiety is dreadful and the worst it has ever been, not helped by the fact I am 53 and in perimenopause/menopause and have a heap of added issues including endometriosis and adenomyosis (HRT made this worse) and helping to care for an elderly parent with advanced dementia - I am exhausted and mentally spent. I am also waiting for surgery for the gynae issues and due to my heightened state of anxiety, I just don't think I can go through with it right now.

I am a hot mess, as they say. I acknowledge this and know full well that I need to make changes and have tried really hard by living as healthy a lifestyle as I can but it's doing sod all for my mental health (and physical it seems). No amount of living well, meditating, counselling and/or cbt is cutting it.

Yet I sit here staring at the bottle of fluoxetine my GP prescribed 2 months ago knowing full well it will more than likely end up in the cupboard with the out of date tablet form of Fluoxetine, the box of Citalopram from 2022, and the Amitriptyline and Sertraline because I am so terrified of any side effects especially a worsening of my gut issues which have taken over my life and made me fearful of going out in case I might suddenly need the loo etc. All the side effects list everywhere for AD state diarrhoea and nausea as the most reported side effect and I just can not risk a worsening of that (and Imodium makes my stomach issues worse before anyone suggests taking it at the same time).

I asked for the liquid form of Fluoxetine because I thought, maybe, I could go in at a really low dose and build up but even that has me in a panicky meltdown whenever I have tried to take it.

I am so fucking angry with myself......so angry.

Please tell me about your experiences with antidepressants, did they help you get a life back on track? Did they not help? Did they make you feel worse than before? Just how can I get over this overwhelming fear of the side effects? I know we are all different and each experience with antidepressants is unique but I don't know what else to do.

OP posts:
Touty · 05/05/2026 12:00

IME they work great for a while and then they don’t.

blankcanvas3 · 05/05/2026 11:55

They have been life changing for me. I’ve been on them for years (with a much lower dosage now) and genuinely, I’m a completely different person whilst on them. I can actually function like a normal human being, which I couldn’t before. I have therapy on the side which is really helpful too and a good tool to help me cope when otherwise I wouldn’t. I’m accepting of the fact I’ll probably be on them for life

wandawaves · 05/05/2026 11:27

Fabulous for me!
I've been taking them about 4 years, due to "shit life syndrome" as a PP put it, everything was just getting too much and I was SO sad and crying all the time, and I tried therapy but it didn't help.

I did have nausea from them for a few weeks, but I persisted as I know that most medication side effects do go away, and yep sure enough the nausea completely disappeared. I didn't have any worsening of mood either, it just started getting better within a few weeks.
I am so glad I started them.

Ketley67 · 05/05/2026 11:06

They’ve changed my life for the better, they’ve seen me through the most awful few years dealing with death, serious illness and redundancy. I just wish I’d been brave enough to start them sooner. No side effects either and I still get anxious, happy, excited etc but it’s proportionate.

Coffeeisnotmycupoftea · 05/05/2026 10:49

YoullWishYourLifeAway · 05/05/2026 10:26

I’ve been on them many years, 3 or 4 different ones. They have actually been lifesaving. I have at times come off them but, after several months, have fallen apart to the point I couldn’t even pick an alternative loaf of bread if my usual one was out of stock!
I have never had side effects from any of them tbh, certainly none that stick in my head.
They enable me to function so that I can go to work, look after DC and have a ‘normal’ life as possible. I don’t kid myself that close colleagues don’t know I have anxiety issues but, for the most part, the general public I deal with daily wouldn’t know I have severe anxiety, OCD, depression etc.

That's where I want to get to. I know that I must come across as a bubbling wreck half the time (I understand the bread situation well), tbh I don't go anywhere anymore and shy away from most social engagements these days so people don't really know what I'm going through, I don't work as a result of my issues.

If antidepressants could offer me something other than this but without suffering from some of the dreadful side effects I've seen mentioned on some sites (including here on the mental health board) then I'd be more than happy even if they were to give me only a small piece of my life back to me.

OP posts:
YoullWishYourLifeAway · 05/05/2026 10:26

I’ve been on them many years, 3 or 4 different ones. They have actually been lifesaving. I have at times come off them but, after several months, have fallen apart to the point I couldn’t even pick an alternative loaf of bread if my usual one was out of stock!
I have never had side effects from any of them tbh, certainly none that stick in my head.
They enable me to function so that I can go to work, look after DC and have a ‘normal’ life as possible. I don’t kid myself that close colleagues don’t know I have anxiety issues but, for the most part, the general public I deal with daily wouldn’t know I have severe anxiety, OCD, depression etc.

Coffeeisnotmycupoftea · 05/05/2026 10:22

inmyhair · 05/05/2026 10:15

The drugs won't make you feel worse. They usually work by numbing your feelings so you don't feel anything.

This was a good thing for me as once my feelings were numbed I could focus on doing what I really needed to do to improve my life.

There's depression, then there's "shit life syndrome" I actually had "shit life syndrome" which was ironically depressing me but I did manage to sort out my issues while my feelings were numbed. It definately helped.

I always say I’m currently stuck in a ‘Shit life syndrome’ situation. There has been so much crap the last 15 years and it’s just getting to me now.

I’d love to feel numb for a while, I’m done with feeling.

OP posts:
Coffeeisnotmycupoftea · 05/05/2026 10:20

Octavia64 · 05/05/2026 10:08

They helped me,

I have endo. I got massive anxiety due to peri menopause which was frankly fucking brutal,

I was in duloxetine (still am).
can’f recommend it enough. Honestly changed my life.

That’s so reassuring, thank you.

I’ve suffered with anxiety all my life and peri has made everything a trillion times worse.

OP posts:
inmyhair · 05/05/2026 10:15

The drugs won't make you feel worse. They usually work by numbing your feelings so you don't feel anything.

This was a good thing for me as once my feelings were numbed I could focus on doing what I really needed to do to improve my life.

There's depression, then there's "shit life syndrome" I actually had "shit life syndrome" which was ironically depressing me but I did manage to sort out my issues while my feelings were numbed. It definately helped.

Octavia64 · 05/05/2026 10:08

They helped me,

I have endo. I got massive anxiety due to peri menopause which was frankly fucking brutal,

I was in duloxetine (still am).
can’f recommend it enough. Honestly changed my life.