Cardiovascular problems are well documented as a side effect of taking Lupron, the worst being congestive heart failure in 1% of patients. Now that can be considered an acceptable risk in the original patient group - men with prostate cancer, for whom Lupron offers a life-saving treatment.
But for the rest? Nothing short of a life-threatening condition should ever cause this to be described.
10 to 29% of patients develop depression.
Bone density in fully one third of the women studied in one project did not return to normal after treatment was stopped.
Side effects include:
tingling, itching, headache and migraine, dizziness, severe joint pain, difficulty breathing, chest pain, nausea, depression, emotional instability, dimness of vision, fainting, weakness, amnesia, hypertension, muscular pain, bone pain, nausea/vomiting, asthma, abdominal pain, insomnia, chronic enlargement of the thyroid, liver function abnormality, vision abnormality, and anxiety, and others.
And others! Including death!
I mean this is seriously fucking dangerous stuff. For 22 years the FDA has known about damaging side effects far beyond those admitted to by the manufacturer. And yet they're doing nothing.
They've known that two of the studies submitted in evidence to get FDA approval falsified 80% of patient data.
And yet the drug has gone on to be prescribed for ever more off-label uses. Now including longterm use in children.
Many of these side effects btw set in after the first use and persist for more than five years after treatment stops.
Anyone who writes an ethical paper considering longterm use of puberty suppressants without exploring these extremely serious safety concerns hasn't done the subject justice.
For anyone who wants to find out more,here's an article exploring the history of problems with Lupron from 2008. 2008! And we know it hasn't gotten any better.