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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Should I increase from 2.5mg to 5mg Mounjaro?

56 replies

UhOhRatPoo · 13/06/2026 11:37

Hi. I know that this question will have been asked within lots of the longer threads but I can’t find a reliable way to search them so I hope some kind person with experience will help me in this new thread.

It’s a simple question really- should I increase my dose to 5mg?

I’m on my third 2.5mg pen having started at 81kg and now down to 76.

I’ve had no digestive side effects but I do wake up most mornings feeling a bit nauseous. It subsides after I’ve been up for a while but it means I can’t stomach breakfast first thing.

I am finding I am never hungry for lunch but do force myself to eat and feel better after I have done. Usually hungry for dinner and still enjoy a beer or a couple of glasses of wine with meal at weekends. Still eating chocolate/desserts in the evening but in smaller portions.

I’d say maybe the appetite suppression is diminishing a little bit but hard to tell. I don’t enjoy not feeling hungry as I am enjoying food less and it reminds me of how you feel when you are unwell and “off your food”. But I am determined to reach a healthy BMI.

Is it worth going up to 5, with the risk of nausea and diarrhoea or is this status quo on 2.5 good enough? I’d like to be 65kg by Christmas. But I can’t afford time off work and school runs etc if I get bad diarrhoea.

OP posts:
UhOhRatPoo · Yesterday 16:06

completelylostagain · Yesterday 15:52

Come back in a few months and tell us if it’s still the same. You have been on MJ a few weeks just. After 18 months I can tell you that I absolutely could eat a 2500 calorie meal if I wanted to.

Well, that’s no difference to not being on it at all then, so may as well save the money?

OP posts:
completelylostagain · Yesterday 16:07

UhOhRatPoo · Yesterday 16:06

Well, that’s no difference to not being on it at all then, so may as well save the money?

Oh it’s very different.

UhOhRatPoo · Yesterday 16:08

completelylostagain · Yesterday 16:07

Oh it’s very different.

How so?

OP posts:
SilenceInside · Yesterday 16:29

I’ve been on Mounjaro for 2 years and absolutely could not eat a 2500 calorie meal even if I really wanted to, not even close.

susiedaisy1912 · Yesterday 16:52

SilenceInside · Yesterday 16:29

I’ve been on Mounjaro for 2 years and absolutely could not eat a 2500 calorie meal even if I really wanted to, not even close.

Now see I can easily eat that when on MJ, although I have to say I’m still only on a 8mg dose weekly because the side effects are too much for me to go any higher at the moment. That’s why I have to track my calories as well as ensuring I hit nutrition goals otherwise I could easily eat that amount. I guess it shows we are all different.

completelylostagain · Yesterday 19:58

UhOhRatPoo · Yesterday 16:08

How so?

You can’t imagine why there might be a difference between using Mounjaro to support healthy choices and trying to do it without? I don’t think there is much point in anyone trying to explain to you as you either can’t or won’t hear it anyway.

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