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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Started Mounjaro- flu symptoms

11 replies

PickledWilly · 16/05/2026 18:15

Started a week and a bit ago. Have felt pretty rubbish all week, freezing, headache and a sort of malaise feeling, like when ill with a virus. By the end of the week I rarely felt like that during the day, but it would come back with a vengeance on the evening. Felt a bit like motion sickness. Have had excellent suppression all week. Did my second jab last night. Have felt horrendous today. I’ve never felt nausea before but assume that’s what this is. This is just the starting 2.5 dose. I intend to stay on this dose a while, but will this get better? Happy to push through if so but feeling quite unwell at the moment!

OP posts:
Gardenflowering · 16/05/2026 18:28

Same.

Its never gone away but is lesser as days go on.

I dread injection day if I’m honest as I feel so nauseated, headaches and feel “flu like” exactly as you describe op.

I didn’t move up through the doses quickly for this reason, take it on a Friday evening so it was less impactful in the working week.

Ive posted similar to your thread OP & very very few have these side effects, those who have some of the side effects say that they do go away and they are fine continuing. So hopefully you will be fine if you persevere.

RedApplePie · 17/05/2026 08:33

I’m 16 weeks in. My first 8 weeks on 2.5 were like this. I went up to 3mg three weeks ago and it’s started again. Mine start about 36 hours post jab and last for about 36 hours then I’m fine. I’ve learned to write off Saturday evenings and Sundays. Last night I went to bed with a thundering headache, needed a hot water bottle I was so cold, and aching all over. Im feeling a bit fragile but much better this morning, so I’m hoping that’s me starting to get used to the slightly higher dose.

Kitt1 · 17/05/2026 11:23

Yes, I was similar for the first couple of weeks after starting and I’ve only gone up by 0.25mg each increase after several weeks on the lower dose.

Also, I eat very clean on the jab day with lean protein and veg and very low carbs and drink lots of water. It seems to help.

Tchamo · 18/05/2026 17:05

PickledWilly · 16/05/2026 18:15

Started a week and a bit ago. Have felt pretty rubbish all week, freezing, headache and a sort of malaise feeling, like when ill with a virus. By the end of the week I rarely felt like that during the day, but it would come back with a vengeance on the evening. Felt a bit like motion sickness. Have had excellent suppression all week. Did my second jab last night. Have felt horrendous today. I’ve never felt nausea before but assume that’s what this is. This is just the starting 2.5 dose. I intend to stay on this dose a while, but will this get better? Happy to push through if so but feeling quite unwell at the moment!

What you're describing — the malaise, the chills, the motion sickness feeling that hits hardest in the evenings — is exactly what week 1-2 looks like for a lot of people. You're not having a bad reaction. Your body is just adjusting to slowed gastric emptying and it tends to pile up by end of day when food has been sitting longer.

The fact that it eased toward the end of last week before coming back after your second jab is actually a good sign — it means your body was already adapting. Most people find weeks 3-4 are noticeably better than week 1-2.

One thing that tends to help today specifically: eat something small and cold within 30-60 minutes of waking — cold Greek yogurt, a banana, anything gentle. Cold food triggers less nausea than hot food because there's less aroma. And sip ginger tea slowly throughout the day rather than drinking anything in volume.

Push through if you can. This part is temporary. Are you managing to keep food and water down okay?

PickledWilly · 18/05/2026 17:15

Tchamo · 18/05/2026 17:05

What you're describing — the malaise, the chills, the motion sickness feeling that hits hardest in the evenings — is exactly what week 1-2 looks like for a lot of people. You're not having a bad reaction. Your body is just adjusting to slowed gastric emptying and it tends to pile up by end of day when food has been sitting longer.

The fact that it eased toward the end of last week before coming back after your second jab is actually a good sign — it means your body was already adapting. Most people find weeks 3-4 are noticeably better than week 1-2.

One thing that tends to help today specifically: eat something small and cold within 30-60 minutes of waking — cold Greek yogurt, a banana, anything gentle. Cold food triggers less nausea than hot food because there's less aroma. And sip ginger tea slowly throughout the day rather than drinking anything in volume.

Push through if you can. This part is temporary. Are you managing to keep food and water down okay?

Thanks for the post - this is really helpful! Saturday was awful (day after 2nd jab) just so nauseous and ill with a terrible headache. Sunday was much better. A few waves of nausea but didn’t last long. Sunday evening I had a bad headache again. Today I have felt fine all day! But do expect to feel rubbish this evening. I’m eating and drinking ridiculously clean. I haven’t been sick once since I started but I am not a vomity person!

it’s great to hear reassurance that things will improve, there have definitely been moments I felt like giving up.

OP posts:
Brenda782 · 02/06/2026 21:49

I felt really fluey and weirdly motion-sick after my first couple of Mounjaro jabs too 😩 especially in the evenings. I’m using it through a medical weight loss programme and mine did settle down after a few weeks once my body got used to it. I found loads of water, smaller meals and taking it easy helped quite a bit while everything settled down.

JournalistEmily · 02/06/2026 21:54

I had this thw first week. Eventually it made me seriously ill and I had to stop. I will never ever use it again

PickledWilly · 02/06/2026 21:57

Brenda782 · 02/06/2026 21:49

I felt really fluey and weirdly motion-sick after my first couple of Mounjaro jabs too 😩 especially in the evenings. I’m using it through a medical weight loss programme and mine did settle down after a few weeks once my body got used to it. I found loads of water, smaller meals and taking it easy helped quite a bit while everything settled down.

Just to update the thread, I did my fourth jab Friday night. I had one day (Sunday) feeling flat and a bit sick and tired. But have felt fine since! Definitely feel my body has got used to it, but my god, it was a strong reaction!

OP posts:
PickledWilly · 02/06/2026 21:57

JournalistEmily · 02/06/2026 21:54

I had this thw first week. Eventually it made me seriously ill and I had to stop. I will never ever use it again

What did it do to you? I hope you have recovered now.

OP posts:
Daineee · 05/06/2026 21:43

I had a rough couple of weeks at the start on Mounjaro, a bit tired, slightly nauseous in the evenings. I used the support in my programme to check in when I wasn’t sure if it was normal, which helped me just ride it out instead of worrying. It did settle once my body adjusted.

Daineee · 08/06/2026 21:55

I had a rough couple of weeks at the start on Mounjaro, a bit tired, slightly nauseous in the evenings. I used the support in my programme to check in when I wasn’t sure if it was normal, which helped me just ride it out instead of worrying. It did settle once my body adjusted.

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