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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

WeGovy - what dose did you increase to?

17 replies

PuzzledObserver · 01/05/2026 22:58

Just that - did you go all the way up to maximum, or stop at a lower level? For how long? Are you still on it? Have you stepped back to a lower dose since reaching goal? Or stopped altogether?

Tell me you dosing experience, basically. Please and thank you.

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Thelondonone · 02/05/2026 03:42

I found it had no impact so went onto mounjaro-save your money.

Mermaidsaremiracles · 02/05/2026 10:27

I'm on month 4 wegovy and it's had strong effects on me. I stayed on the lowest dose for 2 months, then partially increased by click counting in month 3. I have only just gone up to 0.5mg and I am close to my goal weight so will probably stay at this dose for another month or two.

PuzzledObserver · 02/05/2026 11:07

Thank you, both for your replies. Very different experiences, just goes to show individual responses vary massively.

@Mermaidsaremiracles what was your BMI when you started, and what is it now, if you're willing to share?

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Mermaidsaremiracles · 03/05/2026 09:16

PuzzledObserver · 02/05/2026 11:07

Thank you, both for your replies. Very different experiences, just goes to show individual responses vary massively.

@Mermaidsaremiracles what was your BMI when you started, and what is it now, if you're willing to share?

My BMI was 27, a high body fat of 41% and i have high cholesterol / PCOS making me eligible. I am now a BMI of 25 and my body fat currently reads about 37%. I'm quite short so have not needed to lose loads to do this, and it's slow and steady for me. Very pleased with the results so far as I've never managed to stick to anything for so long and the appetite suppression just makes it a lot easier to eat the right things.
X

Perimenoanti · 03/05/2026 20:59

I stayed 2 months on 0.25 and 0.5 each. Moved up to 1mg in the fifth month. 1mg makes me feel full much quicker.

lechatnoir · 03/05/2026 21:17

I’m 3.5 weeks in and not yet noticed the effects on 0.25mg. 4th dose on Tuesday and will see if there’s any extra I can squeeze out before increasing to 0.5 to week after. Very frustrating when you’re paying all this money & take so long deciding I did just assume it would be a magic and instantaneous wand.

bec81 · 03/05/2026 21:24

I spent the first 4 weeks on 0.25mg, then went up to 0.5mg where I stayed until last week when I took 0.75mg. 16 weeks in and almost 15kg down. It certainly works for sone of us

HangryBrickShark · 03/05/2026 21:34

I have found Mounjaro more effective than Wegovy. But Wegovy is its 'poorer cousin' so that might be why. To be honest with the you, using the golden dose M didn't really work out that much more expensive as it could be used for a fifth week but now they've stopped you doing that (spoil sports) 😜 Wegovy is deffo cheaper.

I went from 10mg Mounjaro to 2.4mg of Wegovy which was it's equivalent but originally I stayed on each increased dose on Mounjaro for two months, before going to the next dose up. Going from 2.5mg to 5mg made me feel so nauseous I was chewing stem ginger to stop feeling so sick. So decided after that to stay on each increased dose 2 months. Sometimes I used part of the 'golden dose' to titrate up to the next increase.

I personally feel that sales of Mounjaro will have plummeted due to not only the increased cost but also the fact they prevented the golden dose. Miseries! Get why they've done it though as they were essentially losing a weeks money. Instead people are spacing the dose out to 8 or 9 days. It's no coincidence they instruct you to use the contents within a 30 day time period (because they lose sales otherwise) but anyone with any sense will take that with a punch of salt.

PuzzledObserver · 04/05/2026 12:18

WeGovy is just GLP-1, whereas Mounjaro has another peptide (can’t remember what) as well, so a second mechanism of action. Hardly surprising it’s more effective overall, and effective for some of the people WeGovy doesn’t work for, as it has 2 mechanisms of action.

I have lost a lot of weight already by adopting an intermittent fasting low carb lifestyle, and addressing my compulsive eating. Not easy! But I do feel that I am on top of my dysfunctional eating, and therefore, this time, the weight I’ve lost will stay off. But I have bottomed out, with a BMI of 30. Would just love to get into the top of the healthy weight range, you know?

I was on a different GLP-1, Trulicity (dulaglutide) for type 2 diabetes, for 5 years. I did have some appetite suppression from that, which is why I think I will respond to WeGovy. And it’s cheaper…..

I’m looking to it to support me in a period of therapeutic fasting to get another 2.5 stone or so off. I keep on finding reasons not to do regular fasts, and I am pretty confident they would do the trick for me. And then I would hope to maintain by returning to low carb intermittent fasting. So I see WeGovy as a way to make fasting easier, for a number of months. The fasting is what will get the weight off.

Interesting that only one of the people who’ve responded has used the maximum dose of WeGovy, The others have had good results from lower doses, and one person said it didn’t work for them at all.

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FrothyCothy · 04/05/2026 12:22

I’ve done 2 months at 0.25 and 2 at 0.5, just gone up to 1mg for month 5. Lost two stone (started BMI 38.4, current BMI 34.1 so still a long way to go). Effects definitely wane as time goes on as you might expect, the impact of going up to 1mg this week has been pretty strong!

FrothyCothy · 04/05/2026 12:24

I also haven’t paid more than £100 per pen, which is a big factor for me compared with moving up the doses on MJ, and I have aimed for around 1500 cals a day which will have limited my losses but makes it more manageable for me.

PuzzledObserver · 04/05/2026 13:22

FrothyCothy · 04/05/2026 12:24

I also haven’t paid more than £100 per pen, which is a big factor for me compared with moving up the doses on MJ, and I have aimed for around 1500 cals a day which will have limited my losses but makes it more manageable for me.

Where are you getting it?

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FrothyCothy · 04/05/2026 14:18

PuzzledObserver · 04/05/2026 13:22

Where are you getting it?

I use igovy, sort by cheapest according to which dose I’m after and then change providers every month. It’s a little bit of a faff but worth it for the size of the discounts. DH is also on it so we can sometimes trade a discount code.

Doggymummar · 04/05/2026 14:22

PuzzledObserver · 01/05/2026 22:58

Just that - did you go all the way up to maximum, or stop at a lower level? For how long? Are you still on it? Have you stepped back to a lower dose since reaching goal? Or stopped altogether?

Tell me you dosing experience, basically. Please and thank you.

I. On 1.7 and it's like injecting water. I've gained 10lb in the three weeks I've been on it after losing about ten stone on mounjaro. I have 2.4 for next month but not feeling hopeful.

PuzzledObserver · 04/05/2026 15:15

Doggymummar · 04/05/2026 14:22

I. On 1.7 and it's like injecting water. I've gained 10lb in the three weeks I've been on it after losing about ten stone on mounjaro. I have 2.4 for next month but not feeling hopeful.

Wow. I imagine you’re responding to the GIP in mounjaro, but not so much to the GLP-1, and that’s why WeGovy hasn’t done anything for you yet.

Why did you switch? I’m assuming cost. Will you go back to MJ? Have you tried anything else to deal with your eating behaviour (e.g. therapy, hypnosis, 12 steps)

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blondebombsite13 · 04/05/2026 15:31

I’ve been on it since last September.

I did 0.25 and then stuck at 0.5 with the exception of one month on 1mg.

I had very good results on 0.5 but got impatient, hence 1mg, but then felt I’d jumped the gun so went back down to 0.5mg.

Hoping to come off soon as I have met my target. I haven’t actually had any weight loss for about 3 months now, have obviously hit a natural plateau.

I don’t feel any appetite suppression now, although I really did at first. So hopefully it won’t be too bad when I come off.

WeGovy - what dose did you increase to?
WeGovy - what dose did you increase to?
WeGovy - what dose did you increase to?
PuzzledObserver · 04/05/2026 17:38

Looks like most people getting decent results with 0.5mg and really noticing the difference with 1mg.

Apparently, 0.5mg WeGovy is equivalent to 1.5mg of Trulicity, which is what I was on for diabetes.

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