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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Do you take ‘non regular’ doses? Thinking of doing 6.5mg

18 replies

onyourhandiswritten · 20/01/2026 22:25

I was on 5mg of MJ for about 4 months and then moved on to 7.5mg after 5mg wasn’t enough. After 3 months on 7.5mg, I’d been totally fine but then just started with this awful persistent nausea. Even the sight of the open made me want to 🤮. I moved back down to 5mg but all month I’ve been SO hungry. So it seems 5mg isn’t enough but 7.5mg is too much. I was thinking of counting clicks and doing 6.5mg but everything I read online advises against messing with ‘untested doses’.

Does anyone else count clicks or do ‘non regular’ doses? Have you had any issues?

OP posts:
HappyWineDay · 20/01/2026 22:28

My OH has been on 2.5mg for about 4 months. Tried 3.75mg and felt very nauseous so is currently in 3mg and tolerating well.

gallivantsaregood · 20/01/2026 22:37

I did 2.5, 3.75, 5, 5 every 5 days then 7.5 every 7 days. Suppression is too high so I'm going to dial it back to 7 every 7 days.

PurpleCoo · 20/01/2026 22:47

I'm coming up to a year, and for most of the time it's been a non regular dose. I spent a lot of time of 3.75, and after a spell on 5, went up to 6.25 for quite a while. It's worked really well for me. I never went higher than 7.5 over the whole year so far. I was always a bit scared to go up too much at a time, or to lose weight too quickly/get side effects. I lost weight at steady speed, and never had any side effects (well.except for a week ago when I ate a giant lump of beef when I hadn't eaten red meat for an age)

onyourhandiswritten · 21/01/2026 08:19

Great, thanks. I think I’ll attempt 6.5mg and see how I get on. The nausea on 7.5mg made me totally miserable!

OP posts:
PinkCosYouAreSoVery · 24/01/2026 12:39

Hi, im new to MJ and am wondering how you are doing the non standard doses? I was on wegovy and did count the clicks to get more weeks from a stronger pe, but how does this wrk on MJ? I thought the pens stopped working after 4 goes? Thank you :)

WeAllHaveWings · 24/01/2026 13:57

@PinkCosYouAreSoVery Some info below should capture most points -

🖋️ Using the pen and click counting

Pens are currently filled with around 3ml of medication.2.4ml of this is officially available for use. After 4 normal doses 2.4ml is used and there is around 0.6ml of medication left in the pen which officially should be discarded. Eli Lilly will be reducing the pen fill so there is less left over medication/waste soon.

60 clicks of a pen takes the dose knob to the number 1 in the window and delivers 0.6ml of medication (one full dose by volume; drug strength varies by pen).

Based on logging all clicks for a couple of pens, they seem to be able to deliver around 258 (including priming clicks) before they lock. So for example you could do 8 x 30 click doses = 240 clicks + priming clicks and the pen will not lock.

To work out how many clicks for a dose it is straightforward arithmetic - if you want half a dose, then half the 60 clicks. Very easy to put together an excel to help with this (attached pic of mine for ideas) The biggest risk is not getting your numbers right, or not paying attention - always check twice you are giving yourself the dose you want before injecting. One tip is to mark the number of clicks on the dose knob with a ball point pen first time so you can return to the same place each time.

Remember when partial dosing the guidance to take the same dose (whether it is an increase or decrease) for 4 weeks for it to level off in your system is still sound advice. Adjusting doses every week will make it difficult to understand what level of dose is actually working for you.

If you take more than 5 doses you should be aware you exceed the 30 day in use period with injections on days 0,7,14,21,28,35,42,49 etc. Many do, but risk assess this for yourself as what might be ok for someone is no guarantee it will always be ok for either them or you.

💉Using a syringe

This is not manufacturer or provider recommended and carries higher risk of contamination or dosing error. Also be aware there are unknown risks if using beyond the 30 day in use period. Having syringes available can also be handy if the pen mechanism fails and saves you the hassle of trying to get a partial refund from your provider.

At the end of the current pens (before Eli Lilly reduces the pen fill) you will have left over medication you can use for another dose the following week. This is the same as the rest of the medication in the pen and can be extracted using a syringe.

Buy syringes from a UK pharmacy such as UKMedi (not Amazon). For a fixed syringe look for 1ml 8mm 30-34G syringes. If you want a shorter needle you can buy separate 1ml luer lock syringes and 4mm-6mm 30-34G needles.

Leave the medication in the pen until ready to use and be very careful with hygiene.

A full 60 click dose is 0.6ml. If you are taking a 45 click dose for the pen it will be 0.45ml in a syringe etc

📅 Changing dose schedule

Some people change their dosing schedule away from every 7 days. This will essentially increase or reduce the concentration of the medication in your body. As the medication has a 5 day half-life I personally prefer the routine of every 7 days and adjusting dose, as I feel that keeps the glucose control more consistent. Pharmacists tend to recommend increasing days between doses to reduce effects as they cannot advise off-licence click counting and dose splitting due to professional and safety constraints.

Prescribers will often suggest moving to injecting every 5-6 days temporarily if struggling and to use up a pen before increasing your dose.

Do you take ‘non regular’ doses? Thinking of doing 6.5mg
MoreIcedLattePlease · 24/01/2026 14:09

I've been taking 6mg for several weeks. I started in August and did 2.5mg for 5 weeks, then did a week of 3mg, then 3.75 for 4 weeks before moving up to 5. 5 weeks at 5mg, 2 weeks at 5.62mg and I've been on 6mg for 6 weeks. I think I'm nearly ready to move up again now and I'm toying between trying to do 6.67 before 7.5 (I am buying 10mg pens). I find the slower increase has made my losses more sustainable.

I'm now over 21kg down.

lovealongbath · 24/01/2026 17:42

I am not medically trained to give advice, this is my experience…

started on 2.5mg for 10 weeks, then took 2.8mg, 3mg, 3.3mg, 3.5mg, 3.75mg, 4mg, 4.3mg, 4.5mg, 4.8mg . Then after 1 year of titrating slowly up I reached 5mg. I have been on 5 mg for 8 weeks

PinkCosYouAreSoVery · 25/01/2026 12:23

@WeAllHaveWings thank you, thats kind of you to provide all that info.

Chopsy123 · 25/01/2026 13:03

I started end of August on 2.5mg Mounjaro. I moved from 2.5mg to 3mg so 36 clicks of a 5mg pen at the beginning of November. I’m happy to stay on 3mg for now.

noexcuses26 · 25/01/2026 13:16

Chopsy123 · 25/01/2026 13:03

I started end of August on 2.5mg Mounjaro. I moved from 2.5mg to 3mg so 36 clicks of a 5mg pen at the beginning of November. I’m happy to stay on 3mg for now.

Pls excuse my appalling inability to use maths- how many doses do you get out of the 5mg pen on 36 clicks @Chopsy123- & does that inc the golden dose? Thinking of doing this & it must be more economical than 2.5mg every 6 days which I’m doing currently?

PearlTeapot · 25/01/2026 13:25

I take 3mg out of a 7.5mg pen. (24 clicks)

Chopsy123 · 25/01/2026 13:37

noexcuses26 · 25/01/2026 13:16

Pls excuse my appalling inability to use maths- how many doses do you get out of the 5mg pen on 36 clicks @Chopsy123- & does that inc the golden dose? Thinking of doing this & it must be more economical than 2.5mg every 6 days which I’m doing currently?

I get 7 (36 clicks) doses from a 5mg pen plus a bit left over. I mark the 36 clicks line with a black sharpie so I don’t have to count the clicks every time.

I normally use a syringe to extract the last drops and then work out how much to take out of the next pen using the normal needles, to make 3mg in total.

I have been using the cheap syringes from Amazon although I know they’re not recommended.

gallivantsaregood · 25/01/2026 14:49

PinkCosYouAreSoVery · 24/01/2026 12:39

Hi, im new to MJ and am wondering how you are doing the non standard doses? I was on wegovy and did count the clicks to get more weeks from a stronger pe, but how does this wrk on MJ? I thought the pens stopped working after 4 goes? Thank you :)

It works the same. Around 250 clicks inc printing clicks per pen. Then use an insulin syringe to remove any doses left when clicks no longer work

SENsupportplease · 25/01/2026 14:59

I take 5 from a 15mg pen (so counting clicks) once every 10 days

ProfessorMacandCheese · 25/01/2026 18:41

I've been titrating down, and currently take 2mg from a 5mg pen. I'm going to try spreading out the doses a bit more - will try every 9 days instead of every 7, as still losing a bit which I definitely don't want to be. Will also consider going down a bit further too if that doesn't work.

Kuchta · 25/01/2026 19:13

I have 15 mg pen and taking 5 mg I will use syringes to use all pen .

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