You need to start by doing more research as you’ve made statements that are inaccurate and you should know what you’re planning on taking.
GLP-1 receptor agonist medications have been in clinical use for about 20 years. The first drug in this class, exenatide (Byetta), was approved by the FDA in 2005 for the treatment of type 2 diabetes. This marked the beginning of their therapeutic use in humans. Since then, the class has expanded significantly:
• 2005: Exenatide (Byetta) – first GLP-1 agonist approved for diabetes.
• 2010–2014: Liraglutide (Victoza for diabetes, Saxenda for weight loss).
• 2017 onwards: Semaglutide (Ozempic for diabetes, Wegovy for weight loss).
• 2022–2023: Tirzepatide (Mounjaro/Zepbound), a dual GLP-1/GIP agonist.
So, while the underlying science dates back to the 1970s–1980s (when GLP-1 was first identified), actual human use of GLP-1 medications began in 2005, making it nearly two decades of clinical experience.
Mounjaro mimics two gut hormones (GLP-1 and GIP) to:
• Reduce appetite and slow digestion
• Improve insulin sensitivity and blood sugar control
To be eligible you need to have a BMI ≥30 (or ≥27 with weight-related health issues such as diabetes, hypertension, or sleep apnoea).
It works best alongside a balanced, reduced-calorie diet and physical activity:
Prioritise protein at every meal (e.g., lean meats, eggs, tofu) to maintain muscle.
Include soluble fibre (oats, apples, chia) for digestion.
Stay hydrated and avoid heavy, greasy meals to reduce nausea.
Smaller, slower meals help manage side effects.
Calculate your TDEE and aim for 500 calories below that as your daily allowance. Do not reduce too low or you will feel ill.
Ive been on it since Sept 2024 for T2 diabetes, I’m prescribed by NHS to manage by sugar levels. I’ve lost nearly 7 stone during that time and gone from morbidly obese to healthy BMI, size 22/24 to size 10, BP is normal, cholesterol is normal, HbA1C is in non-diabetic range.
I think it’s fantastic stuff but you need to make that decision for yourself and you need to source your information from reputable sources.