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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Weight loss jabs

33 replies

Georock · 15/12/2025 19:32

After spending past years saying I will definitely never use and they are not for me etc etc. I’m debating whether to just go for it, tbh I’m scared of side effects as I know they haven’t been throughly tested but I’m debating it. Can people on them please guide me? Where do I get from? Which one? How? Even though I am overweight I don’t want to go through doctor as he’s rubbish and this week trying to get an appointment to even discuss has been futile do I won’t go through GP. Please advise me x

OP posts:
Georock · 15/12/2025 19:33

Also will I have to be on them forever? What happens if I stop?

OP posts:
ShawnaMacallister · 15/12/2025 19:34

Try posting on the weight loss injections board. Why do you think they haven't been thoroughly tested?!

spanieleyes · 15/12/2025 19:34

Just go to the weight loss section, there are lots of threads with lots of advice!

spanieleyes · 15/12/2025 19:34

ShawnaMacallister · 15/12/2025 19:34

Try posting on the weight loss injections board. Why do you think they haven't been thoroughly tested?!

Snap!

Georock · 15/12/2025 19:36

Thank you I’ll check it out now. Tbh the biggest thing is the hair loss which is mentioned as a side effect:

OP posts:
Georock · 15/12/2025 19:38

Hair loss on boots website:

Weight loss jabs
OP posts:
ResusciAnnie · 15/12/2025 19:40

I know they haven’t been throughly tested but I’m debating it

Can you elaborate on this please?

Hair loss is a side effect of rapid weight loss, not GLP-1s.

You won’t be able to get them through your doctor unless you have other medical issues.

Start by researching and reading up :)

Lmnop22 · 15/12/2025 19:41

There are possibly side effects for every medication but it’s about balancing those against the net positive of taking the drug. Losing weight will hugely improve your overall health.

You can go on online GP websites and get them prescribed that way if you meet the criteria. If you get side effects that outweigh the benefits, just stop taking them.

My understanding of stopping is that you’ll reach a maintenance dose and keep taking that indefinitely. To discontinue use would increase your appetite back to normal and potentially lead to weight gain if you couldn’t get on top of maintaining your new weight without the drug.

Mounjaro is a good popular one so I would start there!

spookaroo · 15/12/2025 19:41

I’ve tried them, personally I think they’re fucking amazing.

I will accept minor hair loss if it means I didn’t die of obesity or diabetes. Nothing is without side effects. I myself haven’t had any side effects I’m aware of in over a year. But I have got my life back and am now not ruled by food and hunger.

Prelim · 15/12/2025 19:42

It says temporary hair loss, and it’s not a guarantee. Go to the specific board and you’ll get more in depth answers.

Bloozie · 15/12/2025 19:44

They have been thoroughly tested. They’ve been used to manage diabetes for years and years.

Hair loss is real, but a side effect of weight loss, not the drug per se.

The most frequent side effects of the drug are gastro upsets and, less commonly, gallbladder and pancreas issues.

I’ve been using Mounjaro for 6 months and have no side effects. My hair is falling out however. It is what it is.

Georock · 15/12/2025 19:44

ResusciAnnie · 15/12/2025 19:40

I know they haven’t been throughly tested but I’m debating it

Can you elaborate on this please?

Hair loss is a side effect of rapid weight loss, not GLP-1s.

You won’t be able to get them through your doctor unless you have other medical issues.

Start by researching and reading up :)

I have. The exact info on boots and nhs website says they’ve had clinical success and short term tests have been done but there is NO data on long term.

OP posts:
InfoSecInTheCity · 15/12/2025 19:49

You need to start by doing more research as you’ve made statements that are inaccurate and you should know what you’re planning on taking.

GLP-1 receptor agonist medications have been in clinical use for about 20 years. The first drug in this class, exenatide (Byetta), was approved by the FDA in 2005 for the treatment of type 2 diabetes. This marked the beginning of their therapeutic use in humans. Since then, the class has expanded significantly:
• 2005: Exenatide (Byetta) – first GLP-1 agonist approved for diabetes.
• 2010–2014: Liraglutide (Victoza for diabetes, Saxenda for weight loss).
• 2017 onwards: Semaglutide (Ozempic for diabetes, Wegovy for weight loss).
• 2022–2023: Tirzepatide (Mounjaro/Zepbound), a dual GLP-1/GIP agonist.
So, while the underlying science dates back to the 1970s–1980s (when GLP-1 was first identified), actual human use of GLP-1 medications began in 2005, making it nearly two decades of clinical experience.

Mounjaro mimics two gut hormones (GLP-1 and GIP) to:
• Reduce appetite and slow digestion
• Improve insulin sensitivity and blood sugar control

To be eligible you need to have a BMI ≥30 (or ≥27 with weight-related health issues such as diabetes, hypertension, or sleep apnoea).

It works best alongside a balanced, reduced-calorie diet and physical activity:
Prioritise protein at every meal (e.g., lean meats, eggs, tofu) to maintain muscle.
Include soluble fibre (oats, apples, chia) for digestion.
Stay hydrated and avoid heavy, greasy meals to reduce nausea.
Smaller, slower meals help manage side effects.
Calculate your TDEE and aim for 500 calories below that as your daily allowance. Do not reduce too low or you will feel ill.

Ive been on it since Sept 2024 for T2 diabetes, I’m prescribed by NHS to manage by sugar levels. I’ve lost nearly 7 stone during that time and gone from morbidly obese to healthy BMI, size 22/24 to size 10, BP is normal, cholesterol is normal, HbA1C is in non-diabetic range.

I think it’s fantastic stuff but you need to make that decision for yourself and you need to source your information from reputable sources.

SnippySnappy · 15/12/2025 19:53

Life changing. Seriously. I remember being in your position, scared of side effects, and a friend trying to convince me.
I took the leap in the end.
So, so, so worth it.

AmberLime · 15/12/2025 19:59

They've been in regular use for over 15 years. Plenty of research. The suggestion there is not is an urban myth.

Gastro side effects are largely caused by eating greasy, fatty foods while on WLI. Try yo avoid these.

You get them from any UK registered private pharmacy. There are dozens of these. You have to pay.

ShrankLastWinter · 15/12/2025 20:19

The only downside is the cost.

Daisywhatsyouranswer · 15/12/2025 21:36

Georock · 15/12/2025 19:44

I have. The exact info on boots and nhs website says they’ve had clinical success and short term tests have been done but there is NO data on long term.

Huh?they are prescription medications, that were initially in trials for 15 years. Approved by most global regulatory authorities, and the WHO, and In use for over two decades,.

can you link to what boots say? As that’s really odd. Sorry also the nhs? Can you link to that too?

bumptybum · 15/12/2025 21:40

Georock · 15/12/2025 19:44

I have. The exact info on boots and nhs website says they’ve had clinical success and short term tests have been done but there is NO data on long term.

The medication has been used in diabetes care for over 30 years

Daisywhatsyouranswer · 15/12/2025 21:41

I’m completely bemused by this.

op, you need to link to what you’re saying as it is utter nonsense.

TheChosenTwo · 15/12/2025 21:44

Daisywhatsyouranswer · 15/12/2025 21:41

I’m completely bemused by this.

op, you need to link to what you’re saying as it is utter nonsense.

Was thinking the same!

Op I’d suggest maybe steering clear of them if you’re worried. I wasn’t worried, jumped in and never looked back.

PigeonsandSquirrels · 15/12/2025 21:45

They have been thoroughly tested… what do you think happens to get medicine approved??

You get them from a pharmacy - online or in person.

I haven’t had a single side effect in 4 months except heartburn maybe twice.

PigeonsandSquirrels · 15/12/2025 21:47

Georock · 15/12/2025 19:44

I have. The exact info on boots and nhs website says they’ve had clinical success and short term tests have been done but there is NO data on long term.

Loads of medication is used without long term proof yet. My eczema medication for one but nobody harps on about that.

daisydreamies · 15/12/2025 21:53

The side effects I've had have been worth the weight loss. I've spent over 5 years trying to lose weight and following different diets with no success until I started mounjaro. I have noticed I lose more hair, but it's like the amount I lost when I was post partum. As someone else said, weight loss can cause hair loss, so it's not a direct side effect of the drug.

Daisywhatsyouranswer · 15/12/2025 21:55

I think steer clear op too; in fact all prescription meds.

DonicaLewinsky · 18/12/2025 07:52

Georock · 15/12/2025 19:38

Hair loss on boots website:

Hair loss is a risk you are taking if you attempt to lose a significant amount of weight in any way. You will be taking in fewer calories than your body uses, over a sustained period, whether you go for WLI, Slimming World, 5/2 or anything else. That means hair loss is one of the potential consequences.

It's simply a question of deciding what's more important to you, hair or weight. It's ok if it's hair.