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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro - 2 doses and no effect

28 replies

ToddlerTornado · 03/11/2025 20:02

Iv had 2 doses of 2.5mg (the starting dose) due my third tomorrow, i feel exactly the same as when I wasn't on it.

Can anyone tell me how I’m meant to feel? As no change at all currently!

OP posts:
StrongLikeMamma · 13/11/2025 08:29

ToddlerTornado · 03/11/2025 20:53

Im curious to know how people feel when on Mounjaro, does it make you think less about food? Or do you need less to fill you up?

I feel sick and very tired / heavy for the first couple of days after the jab. Like I’m dragging myself around. Am massively put off eating and struggling to eat enough. I’m also completely put off alcohol. I notice I have horrible nightmares the first night of taking it too.

By the end of the week I can go out for dinner, but just stick to things like fish & veg - maybe one glass of wine.

I’m at the middle of week 4 on 2.5mg - so am sticking with this dose. I’m hoping to do this all the way to a healthy BMI - I am happy if the weighloss slows down & would like to be able to come off the drugs with renewed habits if possible! 🤞

Everyone is different though aren’t they. I had to stop taking HRT - because, despite the good effects it had (less pain, better mood, less dizzy) it also had horrible side effects for me (palpitations, weight gain, anxiety) - most of my friends take HRT with absolutely no issue.

So, you win some you lose some I guess

chunkyBoo · 13/11/2025 08:38

Mounjaro half life is 5 days so it will start having a cumulative effect. I have to admit I lost 5.5kg on 2.5mg doses, and 3kg the following month on 5mg so perhaps I have just found it works better for me at lower doses.
I feel fuller, I wake up and think oh breakfast, except my tummy isn’t t feeling it wants anything, often til mid afternoon, then I do feel hungry. I seem to have a bit of a window of 4-5 hours afternoon and early evening so eat then, so I’m kind of also doing the 18 hours fasting also

Zempy · 13/11/2025 08:42

Yes, I always use every last drop from my pens! I have lost over five stone since January and am now 8:5. Keep going, your slow start is nothing to worry about.

I use insulin needles to draw and inject the additional dose. It will probably be more than 6ml, so a good bridging dose between 2.5 and 5mg.

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