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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Tolerance - Mounjaro no longer working after longterm use

27 replies

Mrsmunchofmunchington · 04/09/2025 09:08

I have been on mounjaro for about ten months and it has been really useful.
I've lost a lot of weight but still have about 10kg to lose to get to a bmi of just under 25.

I haven't had any side effects except perhaps mild constipation.
I have moved up the doses as I felt no suppression at all until 7.5mg and then found doses effectiveness wore off after about 8 weeks or so.

I am now on 15mg and starting to feel like it is not as effective anymore.

I do think it still has some effect as I know how much I used to eat pre mounjaro and I don't think I could do that now but the effect isn't enough to help me eat a sufficient deficit to lose anymore weight.

I am disabled and can't exercise.

Also have a restricted range of foods I can eat due to disability, food aversions, plus I am a vegetarian.

I had thought, pre price hikes, that I would perhaps stay on mounjaro for life but I now don't know whether to risk coming off.

It could be that mounjaro is enabling me to pretty much maintain my new weight, even if not actually lose any more.

I am wondering if it does stop working for some people whose bodies are particularly tolerant?

I'm grateful that my body tolerated it so well in that I have never had side effects, and that mounjaro worked so well for me.

Just wanted to ask if anyone else has got to the point where they decided to stop because it wasn't doing enough anymore?

OP posts:
Woompund · 06/09/2025 09:39

Mrsmunchofmunchington · 06/09/2025 09:15

Omg It isn’t magic?!
Well that’s it. I want my money back.

I wasn't replying to you, I was replying to another poster. I went through a short period of trying to use food as a comfort after my mum died last year, and it brought my hunger crashing back, because I was actively working against the drug by causing my blood sugar to spike with what I was eating. The person I was replying to is wasting their time and money by choosing to eat junk food on Mounjaro, they might as well not bother taking it.

mamabeeboo · 07/09/2025 16:40

OP, there's someone I follow on IG who is an embassedor for Oushk and he regularly has Hira on his page. He said 15mg started to not work for him and his pharmacist advised to stop for 4 weeks and start again. I can't remember the dose they suggested to start at, whether it was back at 15 or a lower dose. But something to consider with taking a break.

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