This is not medical advice, just bits and pieces of info I gathered listening to various videos about WLI. It helped me to understand of what's going on, and what to expect, now I am taking MJ.
- Initial dosages are not meant to have weight effect, it is for your body to get used to the medication slowly and to minimalize side effects; most patients start losing weight at 6-8 weeks,
- There may be unrealistic weight loss expectations, typically as studies show, MJ leads to up to 20% or more, for Semaglutide 15 -17% weight loss,
- That weight loss is typically over a year or longer,
- Around 15% of patients are non-responders, they don’t get good results with GLP1 medications, and you don’t know that until you try them,
- Some patients may use compounded form of medication that is different from the manufactured and is less effective.
Some people are slow responders. What is a slow responder? Losing less than 2lb/month. In the studies there were around 10% of patients who lost less than 5% of body weight. Strictly count calories intake, take up exercise, check thyroid function
How can you reduce your chances of pancreatitis:
- Make sure you don’t have gallstones, only Ultrasound can confirm that.
- Check lipids. Ask for blood test which checks triglyceride
- Avoid rapid weight loss
For Peri and Menopausal women amongst us. There may be improving or worsening symptoms of Menopause. With fat loss comes release of Estrogen. Fat has Estrogen in it and when your body breaks down the fat, it releases the estrogen (and other chemicals). Your body needs time to adjust to this fluctuation. But often it can mean feeling better. There are some effects on ovaries and the hormones in general in our bodies. Seek GP advise if you stopped bleeding for some time and you have your period again.
Dry mouth, Xerostomia, one of the theories is that GLP1’s reduces movement of bowels can superficially mimics state of dehydration as a result of a change in appetite, changing blood glucose levels leading to less lubrication in the mouth or acid reflux.
Why do we feel tired or feel lethargic taking GLP1’s?
- Calorie deficit, body is trying to conserve energy
- It’s effect on the gut and the brain. It puts our body into rest and digest state and your body just slows down.
Muscle loss in an indirect effect of this medication due to weight loss we are experiencing, not the medication. It is important to eat proteins in small amount throughout the day to prevent that from happening.
Please correct my comments if I am wrong, or inaccurate. Also add, if possible info from medical sources you found. I hope mine are backed up by research, I tried to check and confirm them as much as I could.