The long term effects of Mounjaro…

[letmeask]

I’m not asking about the long term effects here, I want to ask those who trot this line out across the WLI threads, what sort of long term effects do you think would be present in those who use MJ etc short term? Not everyone plans to stay on the meds long term, so if no damage is done to them whilst taking it, what damage do you think will be done in the 10/20 years after? And for those who do remain on maintenance why do you think they will be badly affected in years to come, but not now?

So you asking a load of non scientists / researchers to speculate on effects of a drug in a couple of decades times?

I’m asking the people who say ‘what about the long term effects?’ to expand. I’m not asking them for science and research I’m asking for their own thoughts.

Concerned that they may be long term side effects to a new drugs is one thing.

Identifying exact effects in two decades time is another!

Are you one of the people who say that? Is that why you are bothered that I’m asking?

Personally I think the long term effects will be not being fat, with all the associated health benefits of that.

If you are asking those who disapprove of fat people getting slim without suffering properly (which I think you are), you’re just going to get a lot of hot air and bluster.

When you read stuff like ‘I expect there will be mass law suits about this in the future’, what they actually mean is ‘I hope there will be, and I can be proved right’.

It’s deeply weird, and unpleasant.

i don’t take and have absolutely no need to lose weight as if anything looking rather scrawny atm. I have zero interest in who takes them and indeed the drug itself.

my point is asking mumsnetters to speculate re what they think effects will be of a drug in two decades times seems somewhat…. Daft and scare mongering

I’m think you have misunderstood me. I’m asking the ‘daft’ mumsnetters who regularly say this to expand. I’m asking the ‘one liners’ to give a bit more. It’s fair enough to ask imo. You seem to have jumped on my question from neutral POV but without quite knowing what I mean. With respect, if you have no interest in the subject this is maybe not the thread for you.

edited to add - I’m not the one doing the scaremongering, thats the people making flippant comments about long term effects

I would think that if someone just uses them short term, then there's unlikely to be much long term effects.

I think that many people seem ott that they will be forever changed by anything thats injected. Hence the fear over vaccines.

Actually the ‘injected’ thought makes a lot of sense.

Huh

I’m not calling mumsnetters “daft”

I’m calling your question “daft”

did you really not grasp that?

Even if you asked a scientist / researcher, they couldn't tell you, they may say, and I'm sure they would that there is nothing that can be foreseen.

As with all new products, the long term effects will only be know much later on - most of the time with pharmaceuticals there are none or very limited effects in the long term.

Exactly… so you’re opening up a thread to the scare mongers to do exactly that - scare monger.

better to not give them a platform

Does it matter what Sue from Stockport thinks might happen in a decade?

If you take the covid vaccine as a case in point - there were greater than expected short term effects, as vaccines go it had a higher than normal incidence of serious side effects in the sort term (but given the scale of its deployment still insignificant) - the clock is ticking on, and none of the doom mongers prophecies of long term issues have materialised, and probably never will be. The early short term issues have largely been addressed, and that's it.

Exactly

it’s all nonsense speculation at this point

so dangerous to give the scare mongers a platform

I think PP above has nailed it - for a lot of the “one liners” it’s because it’s a jab and they’ve swallowed all the COVID anti-vax nonsense hook, line and sinker, so all jabs = bad. It would be the same one line regardless of the injection.

I think there will be people who will struggle to keep the weight off. I'm hoping that won't be me but it's possible. There might be an increase in gallstones as they're linked to substantial weight loss. And there will be more people looking at cosmetic surgery to deal with excess skin.

No, I didn’t. Thanks for clarifying.

just to add though, I was calling them daft

It was fairly evident op

No it doesn’t matter at all. I think I worded this thread badly though as it has been taken the opposite of intended.

i don’t give a fuck what Sue thinks, but I’m asking Sue, instead of banging on about the long term effects, tell us what you think will happen. Sue cannot tell us because Sue knows nothing, is my point.

I’m not giving anyone a platform. They already have it. They are on every other WLI thread talking about the long term effect, I think it’s entirely reasonable to ask them to expand.

Yep, soooo much weirdness from people who have never been overweight fuming that us fatties have finally found a solution. It’s fucking mental and the reason I’ve told no one IRL what I’m doing 🙄

I was part of a drugs trial over 30 yrs ago. It is a drug used for pituitary tumours and in Parkinson’s. It is a very effective drug but after being on the market for 20 years it was found to cause damage to heart valves. The majority of the cases were in patients who were taking higher doses, so those being treated for Parkinson’s. The dose I used to take was very low so not considered a high risk but because I took it for 30 yrs I have been placed on a screening programme. I have an echocardiogram every 3 years to monitor my heart valve condition.

Like GLP-1 drugs, the drug I was on affects the endocrine system and at the higher doses I was initially taking, weight loss was an early side effect. The weight loss was secondary to appetite suppression. At the lower dose it is less effective but always helped weight maintenance. Obviously I did not take the drug for weight issues this was just an observed side effect.

My point is that the major side effect, heart valve damage, was not found during the initial trials, but 20yrs later it led to the withdrawal of the use of the drug in Parkinson’s. It is still an option but this major side effect is considered when looking at the risks.

Mounjaro affects the endocrine system and weight loss is a side effect. Rapid weight loss can cause rapid muscle loss, including the muscle in the heart leading to potential heart failure. Unregulated and unmonitored use of this group of drugs could potentially have long reaching problems. It’s one of the reasons that the NHS use of the drug is being carefully monitored. Unfortunately private use of the drug doesn’t lend itself easily to close monitoring of potential damage through rapid weight loss. Some providers are more careful but it’s obvious from social media that many users are not following guidelines and are keen to abuse the drug to lose weight too rapidly ( quick fix) rather than accepting that it may take 2 or more years to safely lose the excess weight. Alongside over exercising we may be storing up a massive problem with heart disease in the future.

But it won’t stop Sue from spouting crap when really OP… best to not give Sue a platform

You have started a thread explicitly asking for scare mongers to come forth and spout their views