I do. I've lost 94kg so far, starting in March 2022. I got worried about muscle and bone loss because I'm nearing 70 and disabled, so I can't afford to become even more frail and doddery.
After reading about loss of muscle and bone mass on weight loss injections I bought smart scales to keep an eye on what was happening to my body composition as I lost weight.
That was in September 2023 when I had already lost the first 56kg, by which time my body composition was 54.5% muscle and 42.6% fat. 33 months later my body composition is 71.8% muscle and 24.4% fat, and I still have another 3kg to lose before my BMI is below 25 and within the healthy range.
I am too doddery to go for a walk or even to get to a gym and climb on and off the machines. I can't get in and out of chairs if they lack strong armrests to lever myself up and down because my right leg is too support me. I can't get down on the floor and up again without hauling myself up via sturdy furniture. My smartwatch used to nag me about not walking as many steps as others "in my age group" until I set it to congratulate me once I'd managed 1500 steps, and most days I manage around 2000 steps just hobbling around indoors. Sometimes I can't get into the garden because I can't manage the 10cm step down from the back door.
The only exercise I manage regularly is 10 minutes a day on the vibration plate.
Originally I could only sit on a chair and rest my feet on the plate, then I could stand on it with two sticks for support, then one stick, then when I could manage the full 10 minutes without falling over I added hand weights, starting very gently with half kilo weights in each hand, then upgrading to 1kg, and 1.5kg, until now I can manage 10 minutes running through an upper body workout with 2kg weights.
I can't do squats and lunges, because my legs are too feeble, and I still need to hold onto something when climbing on and off the plate, but I am able to heave the top of my heavy ottoman mattress until the pneumatic lift takes over, when previously I had to ask a neighbour for help when I needed to access the storage. So it's definitely having an effect, and the scales say I'm not losing muscle despite having lost 14.8 stones of fat so far.
So I reckon fitter, younger, more mobile women can easily preserve their muscle and bone mass while losing weight on GLP-1 injections. So long as they calculate their protein needs and make sure to hit them every day, even when they have to work hard to manage to squeeze enough grams of protein out of a limited amount of calories.
I wonder how many of the people who have lost muscle and bone mask on weight loss injections were doing resistance training and eating 1.2 to 1.6g of protein per kilo of their own body weight? How many of them had cut out UPFs and prioritised a wide variety of plants and lots of fibre?