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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Rybelsus / semaglutide 7mg Tablets

8 replies

Thislittlekitten · 15/07/2025 23:03

Hi

Im looking for advice from anyone who has taken this at this dosage.

I’ve done 4 weeks on 3mg and about to start the 7mg but want to make a real go of it.

When I started I was really positive and made good changes and choices but that has petered out a bit. I’ve lost no weight which is upsetting as I have made changes.

I am a type 2 diabetic that is why I’m taken it too. Realistically I have 5 stone to lose, I am so overweight. I just don’t know if I have the willpower in me. I’m hoping the tablets shop some of the food noise.

OP posts:
Histoscientist · 16/07/2025 10:49

Most of us on here use the injections through a private prescription.

I was prediabetic for several years HBA1C of 45 and plasma glucose of 5.5 before starting mounjaro in october. I've lost over 3 stones and gone from 13st 1lb to 10st 0.5lbs from bmi 32.4 to bmi 24.8.
My prediabetic symptoms needed a higher dose to resolve, so 10mg which 4 doses up. I haven't had blood tests yet but I know from how I feel that it's gone. I've lost 12cm off my waist and its almkst normal waist to height ratio, as a diabetic you will probably have an apple shaped body and big tummy, so to see that go down is a big achievement.

Can your GP offer you injections?
If not keep moving up until you find an effective dose that helps you eat better and less. I also track my food on myfitnesspal pal and it works out your calories to lose weight.

One of the most important signs for diabetes and prediabetes is the carb or sugar cravings, for me it was carbs, potato in any form, chips, crisps, jacket potatoes, also rice, bread, pasta. Now I rarely eat carbs as the higher doses have stopped these cravings.
Best thing you can do is to reduce carbs and increase your protein, this combination helps with insulin sensitivity and will burn fat quicker. Also drink plenty of water 1-2 litres a day is ideal, water is used to burn fat and also to keep healthy as its involved in all processes. I rarely drank water before mounjaro.

Thislittlekitten · 16/07/2025 10:54

@Histoscientist Thank you for your reply.

I think I will try the course and see what happens then go back.

And yes to the carb issue. This only massive downfall. I can ignore chocolate or sweets. But bread and crisps are my downfall. I know this sounds over the top but I can’t imagine bread not in my life!!

OP posts:
Histoscientist · 16/07/2025 10:59

Thislittlekitten · 16/07/2025 10:54

@Histoscientist Thank you for your reply.

I think I will try the course and see what happens then go back.

And yes to the carb issue. This only massive downfall. I can ignore chocolate or sweets. But bread and crisps are my downfall. I know this sounds over the top but I can’t imagine bread not in my life!!

You can still have it but limit what you have so maybe 2 slices a day max? Yesterday I had a slice of bread for breakfast with cheese spread on. Then for evening I had a fish burger so a bread roll but then I'll go days without bread. So it's just about having less carbs rather than cutting it out completely but you may find on higher doses you won't crave it anymore. I made a chicken salad for lunch with avocado, beetroot, gem lettuce, tomatoes. Before mounjaro, I hadn't had salad for years!

Histoscientist · 16/07/2025 23:37

Also I completely forgot to say, even if you may not have lost weight so far, GLP meds work on correcting insulin sensitivity and correcting insulin resistance/diabetes first. Also the early fat burned is often visceral around the organs so you may not see a visible difference but keep going as it is working hard to help you.

JDM625 · 17/07/2025 00:30

DH was diagnosed with type 2 diabetes last year and started on semiglutide tablets. I never realised it came in a tablet form until then! He too was started on a small dose (3.5mg I think for 1mth) then up to 7mg and his current dose is 14mg a day.

I believe its only been available in tablet form the past few years and both GP and pharmacist have monitored DH closely. DH's had regular bloods tests at GP to check HbA1C along with liver function tests and both the pharmacist and GP calling him to check for symptoms. DH hasn't noticed any issues at all! No idea why anyone would choose the injection form when its the exact, same ingredient in a tablet? I believe the tablet form is only available if type 2 diabetic though.

We made dietary changes when DH was told he was pre-diabetic about 2yrs ago and he started exercising more back then. We both WFH but have always cooked from scratch almost every meal and eat a range of cuisines/meals. On the full 14mg dose, DH does seems to snack less, but he was never a fridge raider type beforehand. He also has more energy and seems keen to try new fitness things. We bought an exercise bike and weights a month ago.

He started the meds about 6mths ago and has lost 14kg, just over 2 stone. GP thinks he should have lost more. DH has a very strong family history on both sides for diabetes and obesity. He walks 5miles most days now, and swims 60 laps when not walking along with starting on the exercise bike recently. He certainly isn't sitting all day, so I'm not sure why he isn't losing more weight?

I'm not sure I've helped at all OP, but you are the only other person I've heard of on the tablet form.

Histoscientist · 17/07/2025 01:01

JDM625 · 17/07/2025 00:30

DH was diagnosed with type 2 diabetes last year and started on semiglutide tablets. I never realised it came in a tablet form until then! He too was started on a small dose (3.5mg I think for 1mth) then up to 7mg and his current dose is 14mg a day.

I believe its only been available in tablet form the past few years and both GP and pharmacist have monitored DH closely. DH's had regular bloods tests at GP to check HbA1C along with liver function tests and both the pharmacist and GP calling him to check for symptoms. DH hasn't noticed any issues at all! No idea why anyone would choose the injection form when its the exact, same ingredient in a tablet? I believe the tablet form is only available if type 2 diabetic though.

We made dietary changes when DH was told he was pre-diabetic about 2yrs ago and he started exercising more back then. We both WFH but have always cooked from scratch almost every meal and eat a range of cuisines/meals. On the full 14mg dose, DH does seems to snack less, but he was never a fridge raider type beforehand. He also has more energy and seems keen to try new fitness things. We bought an exercise bike and weights a month ago.

He started the meds about 6mths ago and has lost 14kg, just over 2 stone. GP thinks he should have lost more. DH has a very strong family history on both sides for diabetes and obesity. He walks 5miles most days now, and swims 60 laps when not walking along with starting on the exercise bike recently. He certainly isn't sitting all day, so I'm not sure why he isn't losing more weight?

I'm not sure I've helped at all OP, but you are the only other person I've heard of on the tablet form.

Edited

The injectables are more effective for weight loss, especially with mounjaro you are expected to lose 16% in 72 weeks, rybelsus is only 5% due to only a few doses available limiting it's effectiveness.
I've actually lost 23.3% in 41 weeks through diet alone, over 3 stones, and I started at 13st 1lb, others starting at a bigger weight lose quicker and more. Mounjaro also shows better reduction in HBA1C compared to rybelsus/semaglutide because it targets an extra GLP receptor.
Best advice for better weight loss is low carbs and high protein. A friend of mine on mounjaro the same time as me has lost half the weight that I have, as she doesn't track calories like myself or increase protein intake, her diet is mainly beige and carb heavy.

Thislittlekitten · 17/07/2025 08:51

Thank you @JDM625 I need to up my exercise I think. I do regular dog walks everyday and I work in a very busy nursery but am on holiday now so need to replace that.

I am a terrible snacker so I need that food noise damped out.

@Histoscientist I am worried I won’t loose weight and feel disheartened. So will keep an eye.

Yesterday was my first 7mg pill. I did feel hungry during the day but after my main meal at 7pm I had a very full slightly uncomfortable feeling and didn’t have anything else to eat. Usually I’d be looking for crisps / toast.

OP posts:
Histoscientist · 17/07/2025 14:43

Thislittlekitten · 17/07/2025 08:51

Thank you @JDM625 I need to up my exercise I think. I do regular dog walks everyday and I work in a very busy nursery but am on holiday now so need to replace that.

I am a terrible snacker so I need that food noise damped out.

@Histoscientist I am worried I won’t loose weight and feel disheartened. So will keep an eye.

Yesterday was my first 7mg pill. I did feel hungry during the day but after my main meal at 7pm I had a very full slightly uncomfortable feeling and didn’t have anything else to eat. Usually I’d be looking for crisps / toast.

Please don't feel disheartened. It may just take time for the weight to come off. Slower is better anyway so you don't get sagging skin. Try advice given, track calories, increase protein and reduce carbs and drink lots of water and I'm sure it will come. Have you checked your tdee? It will give a guide on what to eat for weightloss but the food tracking apps will give a guide too.
You will probably see a change now you're on a higher concentration. Also the most important change is to reduce your blood sugar, so hopefully you will see a difference on your next blood tests and when that comes down it will be easier to eat healthier and lose weight.

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