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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Well this is depressing!

96 replies

Puppylucky · 15/05/2025 08:50

New research published by the Guardian - so not a notable scare monger. Makes my MJ journey feel a bit pointless unfortunately. Edit : it's not letting me share the link for the article which is annoying but the upshot is that studies now show all the weight loss from MJ is regained within a year - much quicker than previously thought. Hey ho.

OP posts:
SundayFundayz · 15/05/2025 08:58

But only based on 1465 people on wegovy / mounjaro?
I don’t know how many people are taking WLI but that seems like a very small percentage?

it defends what you’re doing though… I’m using the injections to get me to a weight where I can exercise more, 3 stone down and I’m now running 5km multiple times a week. I don’t plan on stopping that regardless of injections or not so hoping that will contribute to keeping my weight under control once I’m off them.

or maybe I’ll be on them forever?! Who knows…

OP posts:
AmythestBangle · 15/05/2025 09:03

Well the more positive spin is that maybe this research will bolster the idea of people staying on the medication long term and this will become the norm? Like any other chronic meds.

Never2many · 15/05/2025 09:04

Quell surprise.

The weight loss injection fad is just the same as all the other fad weight loss methods out there which claim to achieve spectacular results.

Yes it may help towards the process. But the only way in which people will lose weight and stay there is through lifestyle changes.

And it’s neither realistic nor reasonable to expect to stay on these drugs for the rest of your life, and neither should it be encouraged.

Moonshinerso · 15/05/2025 09:05

Stop dieting and you regain weight, it’s pretty obvious but doesn’t put me off WLI.

Never2many · 15/05/2025 09:06

AmythestBangle · 15/05/2025 09:03

Well the more positive spin is that maybe this research will bolster the idea of people staying on the medication long term and this will become the norm? Like any other chronic meds.

It’s an insult to anyone with a chronic illness to compare being overweight and to insist that weight loss drugs should be treated as chronic meds.

Unless you have an actual medical condition which means you’re overweight, the vast amount of people who are overweight are so due to their lifestyles.

We shouldn’t be medicating that long term, people need to change their lifestyle to maintain the weight once they’ve lost it.

tryingtobesogood · 15/05/2025 09:06

This is true of many diets, and is at the heart of SW and WW business plans. The diet clubs don’t want us to succeed, they want us to use their business for life. If we put the weight back on it’s not because the changes we made on their diet were unsustainable but because we failed.

WLI cut through a lot of that but we do all need to make lifelong changes to how we eat and move. We have to do the work. And keep doing the work until the changes normalise.

Finallydoingit24 · 15/05/2025 09:07

I don’t think the sample size is the problem because it is likely to be representative at that level. It probably does point towards people needing to be on them in the longer term.
But I will just say that the daily mail published an article with the same research today after yesterday publishing an article about how Sharon Osborne is now unable to gain weight due having taken Ozempic. So frankly who knows.
I have noticed quite a bit of anti-WLI from the press recently after many months of singing its praises.

AmythestBangle · 15/05/2025 09:07

Why should it not be encouraged for some people, if they need it? We don't force people to come off statins, antihypertensive, insulin, antipsychotics, antidepressants, etc etc if they actually need them long term, which some do.

Finallydoingit24 · 15/05/2025 09:08

Never2many · 15/05/2025 09:06

It’s an insult to anyone with a chronic illness to compare being overweight and to insist that weight loss drugs should be treated as chronic meds.

Unless you have an actual medical condition which means you’re overweight, the vast amount of people who are overweight are so due to their lifestyles.

We shouldn’t be medicating that long term, people need to change their lifestyle to maintain the weight once they’ve lost it.

Obesity is a chronic medical condition.

AmythestBangle · 15/05/2025 09:09

Obesity IS a chronic illness,which can have a number of causative factors. Some of which can be treated

SilenceInside · 15/05/2025 09:10

I'd be a bit surprised to regain all the weight I've lost in within a year, as that would be a terrifying yo-yo swing.

This article will absolutely thrill all the weirdos who post on WLI threads to say the usual gubbins about "you'll regain it all and more!".

They're talking about people who lost 8kg or 16kg on average depending on which injection. I've lost over 50kg so far, and continuing. I'm not going to regain that in under a year. I will do everything and anything in my power to stay on my target weight, and not to be obese again. I don't care if I need to stay on Mounjaro or a newer equivalent for life, I am on other medication for life, it is not an issue that people obsess about when it's for other medical conditions.

Mumconnect · 15/05/2025 09:10

There's a thread about it in the maintenance sub on Reddit. It happened to me after a diet 15 years ago, before glp1s.

I think a lot of people on mounjaro are sold a lie. Take this drug, lose 1 stone a month, get to goal and live happily ever after. I think a lot of people are willing to commit to 3 months in time for their summer holiday but not long term. I'm happy losing 1-2lb a week and I know I'll need mj long term.

I think it's just a fact of diets. I have PCOS so I feel like insulin resistance has caused a lot of the weight gain. My metabolic balance is just off without mj.

Definitely find a maintenance friendly provider that will let you stay on mj long term or let you try going it alone with a safety net of recommencing within a year.

Livewell pharmacy, pharmulous, oushk, cloud, swift Dr.

Livewell pharmacy and pharmulous are my personal favourites. Pharmulous are run by a GP on mj herself and they're fantastic. Livewell gave me a fantastic service too and is great that you can just ring them and a pharmacist answers the phone.

AmythestBangle · 15/05/2025 09:11

Many people could also mitigate their lipid levels, mental state, glucose levels, blood pressure and so on by lifestyle changes, we still treat these conditions.

Moonshinerso · 15/05/2025 09:12

Never2many · 15/05/2025 09:06

It’s an insult to anyone with a chronic illness to compare being overweight and to insist that weight loss drugs should be treated as chronic meds.

Unless you have an actual medical condition which means you’re overweight, the vast amount of people who are overweight are so due to their lifestyles.

We shouldn’t be medicating that long term, people need to change their lifestyle to maintain the weight once they’ve lost it.

Being on WLI has reduced my cholesterol and hba1c as well as helping me lose weight which would all turn into chronic conditions that would cost the NHS.

Finallydoingit24 · 15/05/2025 09:12

AmythestBangle · 15/05/2025 09:11

Many people could also mitigate their lipid levels, mental state, glucose levels, blood pressure and so on by lifestyle changes, we still treat these conditions.

Exactly.

AmythestBangle · 15/05/2025 09:15

Would you insist that a chronic schizophrenic or person with severe bipolar disorder come off their medication because their condition is currently well controlled, despite the fact that you know the person to be highly vulnerable to relapse? Why not?

PinkArt · 15/05/2025 09:16

Never2many · 15/05/2025 09:06

It’s an insult to anyone with a chronic illness to compare being overweight and to insist that weight loss drugs should be treated as chronic meds.

Unless you have an actual medical condition which means you’re overweight, the vast amount of people who are overweight are so due to their lifestyles.

We shouldn’t be medicating that long term, people need to change their lifestyle to maintain the weight once they’ve lost it.

The WHO categorises obesity as a chronic, complex disease. Do you think they did that to piss you off, or because it actually is?
It could as easily be said that it's insulting to anyone with obesity to not recognise it as an 'actual' disease and treat it appropriately.
Always fun to hear a different riff on 'lazy fatties pretending they are special and have a medical problem when they just stuff themselves with cake' though. It's been a whole day since the last one.

HansHolbein · 15/05/2025 09:17
Here We Go Again GIF

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ymemanresu · 15/05/2025 09:17

Yes this is depressing and what nearly every single one of us is worrying about.. however there is advice such as reduce your dose slowly then maybe switch to another weight loss drug to maintain. I have always regained the weight from dieting but i have now massively cut alcohol so im hoping this will be a new habit to continue and IF definitely works for me.

MereNoelle · 15/05/2025 09:21

I lost 20kg on Mounjaro last year. 6 months after coming off them, I am still 20kg down. So unless I gain 20kg in the next 6 months I’m fairly sure I won’t have regained the weight in a year.
Like with any diet, I always knew that if I went back to the same habits after coming off the injections then id regain the weight. So I didn’t. I calculated how many calories I needed to maintain my new, lower weight and that’s what I consume. Seems to be working so far.

AmythestBangle · 15/05/2025 09:34

Doctor to patient with bipolar disorder: unfortunately you need to stay on your Lithium and antipsychotics (despite them having potentially life-threatening side effects) because there is a high chance you will relapse into your chronic life-threatening condition if you don't.

Doctor to patient with obesity: you need to come off your WLI medication (which in your case at least is causing very minor side effects) despite the fact that you will almost certainly relapse into your chronic life-threatening condition without it.

This is right, is it @never2many ?

Sampler · 15/05/2025 09:36

@Never2many - there’s always one on these weightloss threads isn’t there.
what the fuck are you doing here ?

Fatmumslim01 · 15/05/2025 09:46

SilenceInside · 15/05/2025 09:10

I'd be a bit surprised to regain all the weight I've lost in within a year, as that would be a terrifying yo-yo swing.

This article will absolutely thrill all the weirdos who post on WLI threads to say the usual gubbins about "you'll regain it all and more!".

They're talking about people who lost 8kg or 16kg on average depending on which injection. I've lost over 50kg so far, and continuing. I'm not going to regain that in under a year. I will do everything and anything in my power to stay on my target weight, and not to be obese again. I don't care if I need to stay on Mounjaro or a newer equivalent for life, I am on other medication for life, it is not an issue that people obsess about when it's for other medical conditions.

I agree @SilenceInside I'm a stone down in 8 weeks on mounjaro which is like a miracle and I'm so grateful for this amazing medicine, I've still got at least another 2-4 stone to go and I'm expecting to be on the medication in some form for life. Just like I will take thyroxine for life to help my dodgy thyroid, I truly believe MJ is helping whatever it is that causes me to overeat and is fixing that so why wouldn't I stay on them in some form as long as I can. Just because my thyroid is now stable doesn't mean I stop the medication for it, it's the same with obesity.

SalfordQuays · 15/05/2025 09:49

I don’t think this should be a surprise. It’s the same with any diet. Mounjaro doesn’t change your personality, so whatever it was that made you over-eat in the first place is still there.

I’ve dieted on and off since I was a teenager. When my willpower is strong I lose weight, then I get bored of it, relax a bit, and gradually the weight comes back on again. Then I get fed up and go on another diet. Ultimately I’m the same person whether I’m losing or gaining weight. The only difference is the presence or absence of will power. It’s exactly the same with mounjaro. Take it away and, for most people, the weight will gradually creep back on. The exception to this will be people who make significant permanent lifestyle changes, and they will be the minority, because it’s bloody hard to do long term.