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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Does anyone take HRT alongside mounjaro?

13 replies

BatChops1 · 04/05/2025 21:46

Just wondered what your experiences of it are

I’m a year into MJ and have been maintaining for 5 months now. I take a maintenance dose of 7.5 and am slowly going to titrate down over the coming months

I’ve lost 5 and a half stone and I’m keen to maintain my current 9 stone 8

Im in the late stages of perimenopause at 53 and im just starting to have symptoms that slightly affect me so its time to really commit to HRT but im concerned about weight gain tbh

I know there is no contra-indications between HRT and MJ so curious as to how others are finding it?

OP posts:
PurpleCoo · 04/05/2025 22:35

I think HRT and MJ complement each other perfectly. MJ seems to reduce peri symptoms further, or removes the ones that HRT didn't help with at all.

With the two together, I feel like I did before peri started. It feels like the missing puzzle piece has been found somehow

Quitelikeacatslife · 04/05/2025 23:22

I just started on MJ and checked with my dr first, she said no problem with hrt

Summerbay23 · 04/05/2025 23:27

Have been on HRT for about 2.5 years (I’m 53). Started MJ a month ago and absolutely no problems in that regard. Am seeing my NHS GP tomorrow so will be interested to see what they say but can’t imagine any issues.

WeAllHaveWings · 04/05/2025 23:28

Quitelikeacatslife · 04/05/2025 23:22

I just started on MJ and checked with my dr first, she said no problem with hrt

It is possible they have not seen the new guidelines yet, mine hadn’t during my 3 month HRT review last week, I had to send them in to her. Worth checking if you are on oral progesterone, especially if you have just started as the advice is to increase oral progesterone dose or change to non-oral when starting WLI and at any dose increase.

non-oral progesterone is not impacted.

Luvvlyjubbly · 04/05/2025 23:59

I’m on both and had no problems at all .

Quitelikeacatslife · 05/05/2025 08:34

@WeAllHaveWings maybe, I’m on evoril conti patches so I’m sure that’s all she took into account .

FortyElephants · 05/05/2025 08:35

I started both at the same time last year so I couldn't tell you if HRT would have caused weight gain but I don't notice any problems taking both.

GustyBaloo · 05/05/2025 10:04

You should be fine with patches, but I know from experience that progesterone orally doesn't really work 😭
I'm on both due to gynae issues.

I started MJ just as I'd given up smoking and started HRT. I'm about 1lb a week, so slightly slow going, but at least it is coming down. I was terrified that giving up smoking and HRT combined were going to add another stone onto me at least!

financialcareerstuff · 05/05/2025 11:09

On both, absolutely fine. 🙂 Feel like the combo is the magic essential blend to reach decent health for me

BatChops1 · 05/05/2025 16:36

Thanks for all your thoughts

I’m working up to it!

OP posts:
Amandaq · 23/08/2025 16:47

I am on my 3rd 10mg pen and have found that progesterone isn’t absorbing (frequent bleeding). Initially they suggested using Utrogestan as a pessary but that is just messy and doesn’t work. Now they suggest increasing the dose, so I am going to try that. But HRT and MJ as a combo is magic!

JustPinkFinch · 23/08/2025 22:31

I lost weight when I started HRT - about 3 kilos. Definitely no gains or worse appetite.

MJ has been started since and has worked really well alongside HRT. You need to avoid oral progesterone really, even though utrogestan is the best kind. Or have the utrogestan dose upped, or use vaginally (off licence).

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