Muscle loss is not inevitable. I'm a frail old lady with limited mobility and I have lost over 12 stone.
My Withings smart scales reassure me each week that my muscle mass is increasing slowly, at the same time as my fat mass continues to decrease.
When I first bought the scales they showed a slight decline in muscle mass the first month. That worried me, because I'm already knackered and don't need to add osteoporosis to my long list of pathetic ailments. So I started eating more protein (adding fish to a diet that had been vegetarian/vegan since 1982) and invested in a set of puny hand weights (0.5kg, 1kg and 1.5kg).
I'm very doddery and stiff with rheumatoid arthritis but I'd been using a vibration plate every day for a year until I was finally able to stand up for a full 10 minute program without needing a couple of sticks for balance (though I still need a stick for support to climb on and off the plate). I started out using the half kilo weights and using the ten minutes of vibration to run through a series of arm exercises and stretches.
A month later the weight loss had continued, but it was all fat, my muscle mass had increased by a tiny amount. Gradually I have increased the size of the weights (still sticking to 10 minutes/day made more intense by the vibration plate). Last Christmas I upgraded to 2 kg weights and they are just heavy enough to be a challenge without being too heavy.
My muscle mass has not decreased since I started using the weights, even though I can't do any exercises that involve bending, squatting, or stepping on and off the plate. Instead it has continued to increase by small amounts each month, while my fat mass has continued to shrink.
I still can't walk without at least one stick, even on a good day, but I can balance on the vibration plate for 10 minutes, and I can just managed to stand up in the greenhouse for a couple of hours potting on seedlings. Best of all I can now open my very heavy Ottoman bed (the mattress weighs 63kgs and the pneumatic lift doesn't kick in until you raise it a good bit) without having to ask one of the neighbours to lend a hand.
My current ambition is to become mobile enough to dodder to the gym and use their machines to strengthen my legs and back. Perhaps then I'd be able to get in and out of chairs that don't have the armrests I currently require to be able to lever myself up and down. Or even get myself up off the floor after a fall without having to crawl along until I can grab onto a piece of sturdy furniture and use it as a climbing frame.
Anyhow if someone as old and knackered as me can halt their muscle atrophy and turn it around despite not being able to walk without sticks and a lot of swearing (because of the pain) then I reckon just about anyone must be able to do it.