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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

How much weight can I lose per month on Mounjaro?

44 replies

justtheonequestion1 · 31/03/2025 14:01

Hello all!

I am strongly considering starting weightless injections (mounjaro) and I am wondering how much weight I can expect to lose per week / month on the medication?

I of course understand that this will vary enormously from person to person. And for context I have a BMI of about 32 so whilst obese I am on the lower level of being obese (unsure If that makes a difference to speed of loss though).

When on the medication I intend to eat relatively healthily, as I am doing so already, don't think I will be doing much exercise though.

Is it realistic to think that I can move to a healthy BMI within 6 months ish?

Thanks for your help!

OP posts:
Pashazade · 31/03/2025 16:36

Started with a bmi of 37.4 at the end of September
Now pretty much at the six month point, still on 5mg
I’ve lost 3st 3lb and bmi is 29.8
I lost a stone in the first month and then it slowed to a sensible levels and I’ve averaged 1-2lbs a week.

ThirdStorm · 31/03/2025 18:25

@justtheonequestion1 i combined, to lose weight I needed to diet and taking the MJ helped me stick to the plan. Without my effort I don’t think I’d have been successful. Keto is my diet of choice but just with a little less fat and more protein. My appetite took a hit in the early days which made dieting much easier. I agree with others about working out your TDEE, that helped me enormously as now I calorie count to stick at goal whilst taking 2.5mg.

Mysticmaiden · 31/03/2025 20:28

I'm 5ft3 started in October at 13st 1lb bmi 32.4, almost 6 months later I'm down to 11st 2lb bmi 27.34 and lost 2 stones. I eat less than my calorie deficit of 1250 and im strict on calories but I have insulin resistance and other inflammatory conditions, so I've noticed 10mg has been the game changer for me with stable blood sugars and consistent losses now and my waist is shrinking finally, been on it 5 weeks now. Basically you don't know how your body will react and lose weight. Drink lots of water and prioritise protein over carbs.

springtimemagic · 22/06/2025 20:02

TragicMuse · 31/03/2025 14:43

What do you think Mounjaro does? By which I mean, how do you think it works?

Because I think you need to understand that the drug itself won’t make you lose anything. It doesn’t act in a vacuum and it’s not a magic fat-melter. The impact it has is on your appetite and feelings of fullness so from a nutritional point of view you’ll need to eat sensibly anyway. But just like any other diet or diet-aid you’ll need to be in a calorie deficit.

Aim for 1-2lbs a month, be supported by Mounjaro in maintaining a calorie deficit and you will succeed. But be aware that it’s not going to do it for you. You need to do the diet-work and Mounjaro is a tool that will make it easier to maintain and not binge.

in estimating your calorie deficit, Losertown is a website that will calculate your TDEE and help you to set your deficit.

I think you mean 1-2 per week, not per month. Because that would be silly.

Weepixie · 22/06/2025 20:08

I’ve lost about a pound a week every week since August the 15th last year and I’m very pleased with that. It’s been hard work but absolutely worth it.

bsaptimdaenr · 22/06/2025 20:42

Ah I commented back in March in this thread that I had lost 4 stone. It’s FIVE AND A HALF now!!

sorry, it was such a boost to read

Gettingbysomehow · 22/06/2025 20:51

I've lost 5 stone and I lost 2lbs a week. I would not recommend losing more unless you want to have no energy and look like a melted candle. Rapid weight loss is not kind on skin. Especially ageing skin.

Lifecircle · 23/06/2025 08:01

I've just completed my 1st month so early days for me.
I started with a BMI of 30.5 and my weight was 11 stone 7lbs. I'm a shortie and ''mature" so I expected to lose weight slowly.
My loss is 7lbs and I'm happy with that and I have lost inches which pleases me as I'm desperately seeking my waist again.
How are you doing op?

Witchyandtwitchy · 24/06/2025 16:06

I started in September last year at 16st! BMI 33.
I’m now 12.9 BMI 26.
I lost a stone in the first month, half a stone in the second then it’s been around 1-2 lbs a week.
Just under a stone to go to reach my goal!

Azureshores · 24/06/2025 16:13

It completely depends on many things - your diet, your calorie intake, your metabolism, your exercise levels etc - everyone's different the same with any weight loss method.

The most I've lost in a month is 10lbs - I've lost 55lbs altogether in 6 months but I've probably lost quicker than most and that's not necessarily healthy. There are people on the thread I'm on who started at the same time as me who've lost half that amount in the same period 🤷‍♀️

Don't compare yourself to others is my advice!

Lazygardener · 24/06/2025 19:29

I'm 8 months in and have lost 50 lbs. I had a very big loss the first month, because I responded quickly to 2.5mg (now on 7.5 mg), after that it's been about a pound a week, sometimes a bit less, sometimes a bit more. I haven't been counting calories, just eating a lot less. I suspect that very soon I will have to be more 'scientific' about it to lose the last 20 pounds. I do see from posts on MN that everyone is different, so it's difficult to say how things will go for you. One thing is for certain though, MJ is a game changer! Good luck.

Dailystreak · 13/06/2026 00:51

Maye88 · 31/03/2025 15:16

I've been on mounjaro since middle of December and have done 4 pens on 2.5mg
I lost 13.8lb on 1st, 11.6lbs on 2nd, 8.2lbs on 3rd and 9.2 on 4th pen. I do 10k steps a day and follow the team rh plan.

For me personally it's been the best thing i have done for myself. It's helping stick to my calorie deficit. Using it as a tool and in process of changing by mindset against food.
The amount you would loose is hard to say because it really does depend on your calorie intake and activity level. But inbound recommend it to anybody that meets the criteria and has done research into it 🙂🙂

Hi, may I ask you what was your calorie intake? If you ever went up from 2.5 mg. I took 2.5 mg for 4 weeks and was tolerating fine but on the 5th week I had so much GI issues and stopped losing so I am curious about people who remained on 2.5 and continued to lose, what was the calorie intake? Thank you

caringcarer · 13/06/2026 01:57

I started Mounjaro at the end of February. I spent first month on 2.5 dose and lost 2 lb. I stayed on 5mg dose for 2 months and I've now lost a total of 1 stone. I've just started the 7.5mg dose and hope to lose 5lb this month. I'll be staying on 7.5 for 8 weeks then moving up to 10mg. As long as I'm losing 5 lbs a month I'll stick to the 10mg dose. If you lose weight too quickly your skin goes baggy. I try to tone up and only titrate up slowly to prevent baggy skin.

Pippingpinge · 13/06/2026 13:44

It’s just a pointless question OP. How long is a piece of string? Some people don’t lose weight at all, some people lose at a very slow rate, perhaps half a pound a week, some lose at a massive rate (usually unhealthy so).

KrazyKatty · 13/06/2026 15:49

Dailystreak · 13/06/2026 00:51

Hi, may I ask you what was your calorie intake? If you ever went up from 2.5 mg. I took 2.5 mg for 4 weeks and was tolerating fine but on the 5th week I had so much GI issues and stopped losing so I am curious about people who remained on 2.5 and continued to lose, what was the calorie intake? Thank you

Why did you resurrect an old thread when there’s loads of current ones you could post on?

Dailystreak · 14/06/2026 11:55

caringcarer · 13/06/2026 01:57

I started Mounjaro at the end of February. I spent first month on 2.5 dose and lost 2 lb. I stayed on 5mg dose for 2 months and I've now lost a total of 1 stone. I've just started the 7.5mg dose and hope to lose 5lb this month. I'll be staying on 7.5 for 8 weeks then moving up to 10mg. As long as I'm losing 5 lbs a month I'll stick to the 10mg dose. If you lose weight too quickly your skin goes baggy. I try to tone up and only titrate up slowly to prevent baggy skin.

Hi, thank you for sharing your journey so far. I am wondering how was your appetite suppression on 2.5 mg and calorie intake vs on 5mg?
And whether you had more appetite suppression on 5 mg and hence you ate less and lost weight or do you think it is the effect of the higher dose that helped you lose weight?

@caringcarer I can’t see the current threads on the same topic.

caringcarer · 14/06/2026 20:15

Dailystreak · 14/06/2026 11:55

Hi, thank you for sharing your journey so far. I am wondering how was your appetite suppression on 2.5 mg and calorie intake vs on 5mg?
And whether you had more appetite suppression on 5 mg and hence you ate less and lost weight or do you think it is the effect of the higher dose that helped you lose weight?

@caringcarer I can’t see the current threads on the same topic.

Edited

On 2.5 for a month I hardly lost anything and I tried to walk more. I had to try really hard not to snack. On 5mg it was easier as I didn't feel as hungry. You have to make sure the food you do eat is good nutrition. On 7.5mg I'm really not hungry at all. Yesterday I had a ham finger rolls about 11am and I had to eat a bit of salmon in lemon juice for dinner but I wasn't hungry and could have easily skipped it. If this continues I'll stay on 7.5mg for 2 months. DH is on Mounjaro journey too and he feels just like I do. He's vegetarian so he has to watch he gets his protein.

Nugg · 14/06/2026 20:18

2.5mg did nothing for me but 5mg I lost a stone in a month with little effort. Two jabs and I almost reduced to 3.75 mg because I literally could not eat but that has evening out and I’m managing to get enough in Me now focusing on protein obviously

RedApplePie · 14/06/2026 20:28

I started 31 Jan with a BMI of 32. I have lost 27lbs to date (so almost half way to goal) and now have a BMI of 27.5. I’ve stayed on a low dose (only moved up to 3mg) recently. I do a lot of strength training though so I’ve got a fair bit of body recomp going on.

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